全文获取类型
收费全文 | 1235篇 |
免费 | 83篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 49篇 |
妇产科学 | 123篇 |
基础医学 | 105篇 |
口腔科学 | 25篇 |
临床医学 | 151篇 |
内科学 | 189篇 |
皮肤病学 | 5篇 |
神经病学 | 120篇 |
特种医学 | 24篇 |
外科学 | 160篇 |
综合类 | 4篇 |
预防医学 | 148篇 |
眼科学 | 15篇 |
药学 | 94篇 |
肿瘤学 | 99篇 |
出版年
2024年 | 2篇 |
2023年 | 9篇 |
2022年 | 26篇 |
2021年 | 49篇 |
2020年 | 21篇 |
2019年 | 45篇 |
2018年 | 41篇 |
2017年 | 36篇 |
2016年 | 31篇 |
2015年 | 31篇 |
2014年 | 51篇 |
2013年 | 52篇 |
2012年 | 72篇 |
2011年 | 105篇 |
2010年 | 52篇 |
2009年 | 41篇 |
2008年 | 60篇 |
2007年 | 78篇 |
2006年 | 61篇 |
2005年 | 74篇 |
2004年 | 59篇 |
2003年 | 47篇 |
2002年 | 52篇 |
2001年 | 23篇 |
2000年 | 14篇 |
1999年 | 19篇 |
1998年 | 11篇 |
1997年 | 11篇 |
1996年 | 7篇 |
1995年 | 10篇 |
1994年 | 5篇 |
1993年 | 6篇 |
1992年 | 11篇 |
1991年 | 9篇 |
1990年 | 12篇 |
1989年 | 13篇 |
1988年 | 6篇 |
1987年 | 9篇 |
1986年 | 11篇 |
1985年 | 9篇 |
1984年 | 2篇 |
1983年 | 8篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1978年 | 4篇 |
1977年 | 4篇 |
1944年 | 2篇 |
1939年 | 5篇 |
1912年 | 1篇 |
1911年 | 1篇 |
排序方式: 共有1320条查询结果,搜索用时 15 毫秒
1.
2.
Robert G. Frank Allyson E. Haut Megan Smick Marc W. Haut John M. Chaney 《Brain injury : [BI]》1990,4(3):289-295
Cognitive deficits associated with closed head injury (CHI) have been well studied. Less attention has been directed to the emotional consequences of CHI and subsequent attempts to cope with major life events. CHI typically constitutes a catastrophic injury, yet few studies have examined coping strategies used by individuals after CHI or the effects of CHI on family functioning that may mediate coping. Previous workers have speculated that time since injury is a crucial determinant of coping; however, this has not been investigated with regard to CHI. In this preliminary investigation, 40 patients with CHI were compared with 17 neurologically intact controls. The CHI group was divided into two groups according to time since injury. It was found that patients with CHI used information seeking as their most dominant coping strategy regardless of their time since injury. Patients with CHI had higher family cohesion scores than control subjects. Implications of these findings for psychological response to CHI are discussed. 相似文献
3.
4.
5.
6.
Pelvic radiation with concurrent chemotherapy compared with pelvic and para-aortic radiation for high-risk cervical cancer 总被引:55,自引:0,他引:55
Morris M Eifel PJ Lu J Grigsby PW Levenback C Stevens RE Rotman M Gershenson DM Mutch DG 《The New England journal of medicine》1999,340(15):1137-1143
BACKGROUND AND METHODS: We compared the effect of radiotherapy to a pelvic and para-aortic field with that of pelvic radiation and concurrent chemotherapy with fluorouracil and cisplatin in women with advanced cervical cancer. Between 1990 and 1997, 403 women with advanced cervical cancer confined to the pelvis (stages IIB through IVA or stage IB or IIa with a tumor diameter of at least 5 cm or involvement of pelvic lymph nodes) were randomly assigned to receive either 45 Gy of radiation to the pelvis and para-aortic lymph nodes or 45 Gy of radiation to the pelvis alone plus two cycles of fluorouracil and cisplatin (days 1 through 5 and days 22 through 26 of radiation). Patients were then to receive one or two applications of low-dose-rate intracavitary radiation, with a third cycle of chemotherapy planned for the second intracavitary procedure in the combined-therapy group. RESULTS: Of the 403 eligible patients, 193 in each group could be evaluated. The median duration of follow-up was 43 months. Estimated cumulative rates of survival at five years were 73 percent among patients treated with radiotherapy and chemotherapy and 58 percent among patients treated with radiotherapy alone (P=0.004). Cumulative rates of disease-free survival at five years were 67 percent among patients in the combined-therapy group and 40 percent among patients in the radiotherapy group (P<0.001). The rates of both distant metastases (P<0.001) and locoregional recurrences (P<0.001) were significantly higher among patients treated with radiotherapy alone. The seriousness of side effects was similar in the two groups, with a higher rate of reversible hematologic effects in the combined-therapy group. CONCLUSIONS: The addition of chemotherapy with fluorouracil and cisplatin to treatment with external-beam and intracavitary radiation significantly improved survival among women with locally advanced cervical cancer. 相似文献
7.
Jeoffrey A. Bispham Allyson S. Hughes Ludi Fan Magaly Perez-Nieves Alicia H. McAuliffe-Fogarty 《Clinical Diabetes》2021,39(2):153
There is a dearth of research characterizing the impact on a caregiver’s sleep when caring for a minor with type 1 diabetes. This study used focus groups of people with type 1 diabetes and caregivers of minors with type 1 diabetes to explore the experience of how diabetes affects sleep. The occurrence of both unanticipated and planned sleep disruptions led to the majority of participants reporting that their sleep was considerably affected by diabetes. Despite the improvement in blood glucose management that diabetes technology devices can provide, people with type 1 diabetes and their caregivers still report sleep disruption and sleep loss resulting from overnight diabetes management.The daily self-management behaviors involved in living with type 1 diabetes can be more difficult overnight for people with type 1 diabetes, caregivers, and other household members and can lead to sleep disruptions and emotional experiences such as worrying about severe hypoglycemia occurring during sleep. On average, people with type 1 diabetes experience nocturnal hypoglycemia 25% of the time (1). Emotional experiences can also include fear of hypoglycemia, which refers to extreme worry and anxiety-like symptoms experienced by people living with type 1 diabetes and their caregivers regarding hypoglycemia. Such feelings can result in negative diabetes management behaviors and negatively affect quality of life (2,3). Disturbances caused by diabetes device alarms and fear of hypoglycemia are common barriers to sleep for people with diabetes (4). Research suggests that interventions should be developed to target overnight glycemic management and fear of hypoglycemia to improve sleep quality (5). 相似文献
8.
McKee KJ Whittick JE Gilhooly MM Ballinger BR Gordon DS Mutch WJ Philp I 《Health & social care in the community》1999,7(2):100-108
Research has revealed the importance of characteristics of the supporter, the care-recipient, and circumstances of caregiving in the success or failure of community-based care of older people. The Dundee Study of Carers and Dementia examined factors associated with the maintenance and care of older people in the community, and with the impact of dementia on family supporters. Two hundred and twenty-eight family supporters of community-resident older people (≥65) (50% with dementia, 50% without, matched for age and sex) were interviewed. Supporters' responses to their relative's condition and circumstances, their ways of coping with stressful caregiving problems, and their willingness to continue their caregiving role, were assessed. Findings indicated that willingness to care and stress were associated in different ways with the supporter's response to his/her relative. Coping was found to be significantly associated with stress, response to relative, and willingness to care in only three out of a total of 45 tests. Willingness to care was positively associated with the coping behaviour internalization. The findings are discussed in the context of developing interventions for improving the well-being of supporters of an older relative in the community. 相似文献
9.
10.
Patricia J Eifel Kathryn Winter Mitchell Morris Charles Levenback Perry W Grigsby Jay Cooper Marvin Rotman David Gershenson David G Mutch 《Journal of clinical oncology》2004,22(5):872-880
PURPOSE: To report mature results of a randomized trial that compared extended-field radiotherapy (EFRT) versus pelvic radiotherapy with concomitant fluorouracil and cisplatin (CTRT) in women with locoregionally advanced carcinomas of the uterine cervix. PATIENTS AND METHODS: Four hundred three women with cervical cancer were randomly assigned to receive either EFRT or CTRT. Patients were eligible if they had stage IIB to IVA disease, stage IB to IIA disease with a tumor diameter > or = 5 cm, or positive pelvic lymph nodes. Patients were stratified by stage and by method of lymph node evaluation. RESULTS: The median follow-up time for 228 surviving patients was 6.6 years. The overall survival rate for patients treated with CTRT was significantly greater than that for patients treated with EFRT (67% v 41% at 8 years; P <.0001). There was an overall reduction in the risk of disease recurrence of 51% (95% CI, 36% to 66%) for patients who received CTRT. Patients with stage IB to IIB disease who received CTRT had better overall and disease-free survival than those treated with EFRT (P <.0001); 116 patients with stage III to IVA disease had better disease-free survival (P =.05) and a trend toward better overall survival (P =.07) if they were randomly assigned to CTRT. The rate of serious late complications of treatment was similar for the two treatment arms. CONCLUSION: Mature analysis confirms that the addition of fluorouracil and cisplatin to radiotherapy significantly improved the survival rate of women with locally advanced cervical cancer without increasing the rate of late treatment-related side effects. 相似文献