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Alfred Niyokwishimira Jean de D. Baziki William G. Dundon Nick Nwankpa Cecilia Njoroge Hiver Boussini Henry Wamwayi Baboucarr Jaw Giovanni Cattoli Cansius Nkundwanayo Dsir Ntakirutimana David Balikowa Lionel Nyabongo Zhidong Zhang Sanne Charles Bodjo 《Transboundary and Emerging Diseases》2019,66(5):2067-2073
In December 2017, Peste des Petits Ruminants (PPR) emerged in Burundi (East Africa) and rapidly spread to five provinces (Gitega, Kirundo, Mwaro, Muramvya and Karuzi) in the country, causing severe disease and killing more than 4,000 goats in the province of Gitega alone. An initial outbreak investigation was conducted in December 2017 by the Burundi Government Veterinary Services and samples were collected for laboratory confirmation. A competitive Enzyme Linked Immuno‐Sorbent Assay (cELISA: Chinese Patent No. ZL201210278970.9) supplied by the Lanzhou Veterinary Research Institute was used to test 112 sera and results showed around 37.5% positive samples. This high level of PPR positive sera in an animal population where PPR infection and vaccination had not been previously reported indicated the exposure of the animals to PPRV. Subsequently in January 2018, the laboratory tests conducted at the African Union‐Pan African Veterinary Vaccine Centre (AU‐PANVAC) laboratories following a joint investigative mission by the African Union‐Interafrican Bureau for Animal Resources (AU‐IBAR), AU‐PANVAC and the East African Community (EAC) confirmed the presence of PPR in Burundi. Samples tested by conventional RT‐PCR indicated the presence of the PPR virus (PPRV). Confirmatory isolation of the virus was also performed. Phylogenetic analysis revealed that the virus belongs to lineage III and shows a close relationship with PPRV isolates from Kenya in 2011 and Uganda in 2012. A possible explanation for the outbreaks of PPR in Burundi between December 2017 and February 2018 is presented. 相似文献
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John A. Kalapurakal Mahesh Gopalakrishnan David O. Walterhouse Cynthia K. Rigsby Alfred Rademaker Irene Helenowski Sandy Kessel Karen Morano Fran Laurie Ken Ulin Natia Esiashvili Howard Katzenstein Karen Marcus David S. Followill Suzanne L. Wolden Anita Mahajan Thomas J. Fitzgerald 《International journal of radiation oncology, biology, physics》2019,103(1):28-37
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Frank H. C. Cheng Hon‐Yi Lin Tzy‐Wei Hwang Yin‐Chen Chen Rui‐Lan Huang Chia‐Bin Chang Weiqin Yang Ru‐Inn Lin Ching‐Wen Lin Gary C. W. Chen Shu‐Yuan Mai Jora M. J. Lin Yu‐Ming Chuang Jian‐Liang Chou Li‐Wei Kuo Chin Li Alfred S. L. Cheng Hung‐Cheng Lai Shu‐Fen Wu Je‐Chiang Tsai Michael W. Y. Chan 《Cancer science》2019,110(3):1085-1095
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Daniel A. Hartman Lauren M. Rice Justin DeMaria Erin M. Borland Nicholas A. Bergren Anna C. Fagre Lucy L. Robb Colleen T. Webb Rebekah C. Kading 《Transboundary and Emerging Diseases》2019,66(4):1709-1717
Rift Valley fever virus (RVFV) poses a major threat of introduction to several continents, including North America. Such an introduction could cause significant losses to the livestock industry, in addition to substantial human morbidity and mortality. Because of the opportunistic blood host selection of Culex tarsalis mosquitoes, we hypothesized that this species could be an important bridge vector of RVFV near feedlots in the event of an introduction. We investigated the mosquito community composition at livestock feedlots and surrounding natural and residential areas to determine differences in mosquito relative abundance and blood feeding patterns attributed to cattle feeding operations. DNA extracted from abdomens of blood‐fed mosquitoes were sequenced to determine host identity. Multivariate regression analyses revealed differences between mosquito community assemblages at feedlots and non‐feedlot sites (p < 0.05), with this effect driven largely by differential abundances of Aedes vexans (padj < 0.05). Mosquito diversity was lower on feedlots than surrounding areas for three out of four feedlots. Culex tarsalis was abundant at both feedlots and nearby sites. Diverse vertebrate blood meals were detected in Cx. tarsalis at non‐feedlot sites, with a shift towards feeding on cattle at feedlots. These data support a potential for Cx. tarsalis to serve as a bridge vector of RVFV between livestock and humans in Colorado. 相似文献
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Cherie Rushton Andrew Jackson Kathryn Goddard Arun Alfred 《Journal of clinical apheresis》2019,34(1):73-74
Extracorporeal photopheresis (ECP) is a cell based immunomodulatory therapy in which the patient is attached intravenously to a cell separating machine. During ECP a patient's blood is collected via either a central venous access device (CVAD) or a peripherally inserted 16G arterial venous fistula needle in either one or both antecubital fossa. However, patients presenting for ECP with GVHD repeatedly present a challenge to the ECP team due to poor venous access resulting from previous therapies and skin changes. The use of peripherally inserted central venous catheters (PICCs) offers an alternative route of vascular access for this cohort of patients. Here we present a case report of a patient successfully treated with ECP following the insertion of a PICC line. 相似文献
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Wen Chen Yun Zhao Xing Xie Jihong Liu Jingran Li Chao Zhao Shaoming Wang Xueyan Liao Qiong Shou Minghuan Zheng Alfred J Saah Lihui Wei Youlin Qiao 《Vaccine》2019,37(6):889-897