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排序方式: 共有535条查询结果,搜索用时 150 毫秒
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Maryam Beheshtian Zohreh Fattahi Mahsa Fadaee Raheleh Vazehan Payman Jamali Elham Parsimehr Mahboubeh Kamgar Mehrshid Faraji Zonooz Shokouh Sadat Mahdavi Zahra Kalhor Sanaz Arzhangi Seyedeh Sedigheh Abedini Farahnaz Sabbagh Kermani Faezeh Mojahedi Vera M. Kalscheuer Hans-Hilger. Ropers Ariana Kariminejad Hossein Najmabadi Kimia Kahrizi 《Clinical genetics》2019,95(6):718-725
Neurodevelopmental delay and intellectual disability (ID) can arise from numerous genetic defects. To date, variants in the EXOSC gene family have been associated with such disorders. Using next-generation sequencing (NGS), known and novel variants in this gene family causing autosomal recessive ID (ARID) have been identified in five Iranian families. By collecting clinical information on these families and comparing their phenotypes with previously reported patients, we further describe the clinical variability of ARID resulting from alterations in the EXOSC gene family, and emphasize the role of RNA processing dysregulation in ARID. 相似文献
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Meftahi Gholam Hossein Jangravi Zohreh Sahraei Hedayat Bahari Zahra 《Inflammation research》2020,69(9):825-839
Inflammation Research - Novel Coronavirus disease 2019 (COVID-19), is an acute respiratory distress syndrome (ARDS), which is emerged in Wuhan, and recently become worldwide pandemic. Strangely,... 相似文献
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Mona Seyed Attaran Zohreh Sharifi Seyed Masoud Hosseini Shahram Samei Zahrah Ataee 《APMIS : acta pathologica, microbiologica, et immunologica Scandinavica》2014,122(3):243-247
Hepatitis delta virus (HDV) is a satellite virus that needs hepatitis B virus (HBV) surface antigen for amplification and transition. HDV appears in HBsAg carriers as acute coinfection and superinfection in patients with chronic hepatitis B. This coinfection leads to chronic hepatitis, cirrhosis, and liver carcinoma. The aim of this study was to detect the prevalence of coinfection and superinfection of HBVs and HDVs in blood donor individuals in Iran. Sera from 854 asymptomatic blood donors from the Bank of positive samples storage at the National Blood Transfusion Organization of Iran that were positive for hepatitis B surface antigen were analysed. The presence of antibody against HDV in blood donors was detected using ELISA followed by conventional PCR, seminested PCR and real‐time PCR to determine coinfection and/or superinfection. Restriction fragment length polymorphism was used for HDV genotyping. All 854 samples were HBsAg and anti‐HBc positive whereas only 18 (2%) of them were positive for anti‐HDV. Of the 854 samples, 154 (18%) were HBV‐DNA positive. HDV‐RNA was detected in 0.6% of the total samples by seminested PCR and real‐time PCR and the two PCR methods produced similar results. Moreover, 16.6% and 83.4% of anti‐HDV‐positive samples exhibited coinfection and superinfection with HBV, respectively. Genotype I of HDV was determined in positive samples. 相似文献
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Zahra Aryan Negar Mahmoudi Ali Sheidaei Shahabeddin Rezaei Zohreh Mahmoudi Kimyia Gohari Nazila Rezaei Mohammad Javad Hajipour Arezou Dilmaghani-Marand Farideh Razi Mahdi Sabooni Farzad Kompani Alireza Delavari Bagher Larijani Farshad Farzadfar 《Journal of clinical lipidology》2018,12(6):1471-1481.e4
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Ravi M. Shah Reem Elfeky Zohreh Nademi Waseem Qasim Persis Amrolia Robert Chiesa Kanchan Rao Giovanna Lucchini Juliana M.F. Silva Austen Worth Dawn Barge David Ryan Jane Conn Andrew J. Cant Roderick Skinner Intan Juliana Abd Hamid Terence Flood Mario Abinun Mary Slatter 《The Journal of allergy and clinical immunology》2018,141(4):1417-1426.e1