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1.
Eight patients with endobronchial tuberculosis diagnosed on bronchoscopy were treated with antituberculosis drugs and a course of prednisone. The progress of the endobronchial lesions was assessed on repeated examinations. The course of the disease was variable and the endobronchial narrowing improved in two patients only. Hypersensitivity reactions associated with initiation of antituberculosis treatment may constitute a special group where corticosteroid is indicated. In other situations, the usefulness of corticosteroid for treatment of endobronchial tuberculosis is not well documented.  相似文献
2.
全反式维甲酸致高白细胞症作用机理的初步研究   总被引:2,自引:0,他引:2  
Chen H  Sun G  Li J 《Zhonghua yi xue za zhi》1998,78(4):284-286
目的探讨全反式维甲酸(ATRA)在体内促外周血白细胞增高作用的细胞生物学机制。方法用3HTdR掺入,祖细胞培养和脾集落形成单位(CFUS)测定等方法,观察在ATRA作用下BALB/C小鼠造血功能的动态变化。结果ATRA可以增加小鼠外周血细胞计数,第8天白细胞计数上升,第16天为对照的183%。骨髓细胞增殖活性增加,3HTdR掺入增多,掺入高峰第8天,为对照的190%,CFUS增殖,12天为对照200%。造血祖细胞粒巨噬细胞集落(CFUGM)增殖,第12天为对照的215%。结论ATRA在小鼠体内具有致白细胞增高作用,这可能与其在体内促CFUGM和CFUS增殖并定向粒系分化有关,与其作用于体内释放造血活性物质如粒细胞集落刺激因子有关。  相似文献
3.
TT病毒与原发性肝细胞癌发病的关系   总被引:1,自引:0,他引:1  
目的探讨TT病毒(TTV)感染与原发性肝细胞癌(HCC)之间的关系.方法使用第二代TTV PCR引物,从112例HCC患者、95例无HCC的慢性肝病(CLD)患者及30例健康志愿者血清中检测TTV,每份DNA样本均取自50μl血清.记录各组患者的临床特点(性别、年龄、肝功能、肿瘤特性、其他肝炎病毒指标和输血史),并分析其与TTV感染的关系.结果 (1)TTV DNA在HCC患者的阳性检出率为17.86%(20/112),与在无HCC的CLD患者中的阳性检出率15.78%(15/95)相比,差异无显著性,但均较正常对照组有显著差异(P<0.05);(2)在输血史这一临床特征上,HCC和CLD组内,TTV DNA阳性与阴性组之间差异有显著性,分别为80.00%vs 35.87%(P<0.05)和73.33% vs 27.50%(P<0.05);(3)在HCC患者中,TTV DNA阳性组丙氨酸氨基转移酶(ALT)较阴性组有显著升高,[(93±27)IU/L vs (68±31)IU/L](P<0.05),且TTV DNA的存在造成同时合并HBV和/或HCV感染的HCC患者ALT的显著升高(P<0.05);(4)在CLD患者中,有无TTV DNA的存在,对HBV和/或HCV所致的肝功能损伤并无显著性影响.结论 TTV这种可能经过血液传播的肝炎病毒可造成HCC患者的肝功能损伤,但在CLD向HCC的转化中,似乎不起主导作用.  相似文献
4.
A case of human pregnancy and birth after transfer of a donated embryo fertilized in vitro is reported. The ovulatory cycles of the donor and recipient were synchronized by induction of owla- tion. The donor was a 29-year-old woman with prim- ary infertility, from whom 11 00cytes were recovered after stimulation with gonadotropins. The recipient was a 29yearold woman with secondary infertility because of bilateral tubal ligation performed nine years ago and she failed in a trial of the in vitro fertilization program* Six of the 11 00cytes from the donor were fertilized and underwent cleavage. Three of the six embryos were returned to the donor and the others were transferred to the recipient. No pregnancy occurred in the donor but pregnancy was confirmed in the recipient and a normal healthy male baby weighing 3 000 g was safely born. Key issues and indications of donated embryo transfer are dis- cussed in detail.  相似文献
5.
ObjectiveToaddresswhethercirculatingTcelsfromthepatientswithprimaryandmetastaticmalignantmelanomashowalteredchemotaxistomono...  相似文献
6.
Effects of Cordyceps sinensis on murine T lymphocyte subsets.   总被引:1,自引:0,他引:1  
It was shown by flow cytometry analysis that crystalized preparation of Cordyceps sinensis (Cs-Cr) caused significant elevation of the number of T helper cells and Lyt-1/Lyt-2 (T helper to T suppressor cell) ratio both in peripheral blood and the treated mice spleen. The spleen weight, phagocyte counts and phagocytic activity were also elevated in the treated group. In addition, Cs-Cr could protect T helper cells from the immunosuppressive effects of prednisolone acetate and cyclophosphamide. These results further substantiate the fact that Cs-Cr is an immunoregulator/biological response modifier of cellular immunity and may be potentially useful in handling immunodeficient or immunosuppressed patients.
  相似文献
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8.
本文总结了首都医科大学附属北京佑安医院传染病学临床见习带教经验,并密切结合传染病的现状,为提高传染病学临床带教水平,让学生在短时间内克服恐惧心理,获得最大程度的收益提出了几点建议。  相似文献
9.
分析307例(542例)鼻窦炎性疾病窦内窥镜手术中和术后的并发症发生情况。结果:(1)主要并发症为出血过多、纸板损伤、眶内出血、上颌窦口狭窄和术腔粘连。(2)术中并发症除出血过多外,最常见眶并发症;严重并发症仅有1例脑脊液鼻漏并化脓性脑膜炎。93)术中并发症的历年平均发生率为100例30.6次,术后并发症的历年平均发生率为每100例35.9次。各项并发症的年度发生率呈逐年下降趋势。讨论了主要并发症  相似文献
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