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Abstracts of the 25th International Isotope Society (UK Group) symposium: Synthesis and applications of labelled compounds 2016 下载免费PDF全文
E. Aboagye K. Alger S.J. Archibald N.B.A. Bakar N. Barton J. Bergare J. Bloom R. Bragg B.P. Burke M.J. Burns L. Carroll D.G. Calatayud C. Cawthorne F. Cortezon‐Tamarit C. Crean M.P. Crump J.R. Dilworth J. Domarkas S.B. Duckett I. Eggleston C.S. Elmore E.M. van Es M. Fekete M. Goodwin G.G.R. Green G. Grönberg C.J. Hayes M.A. Hayes S. Hollis R. Hueting P. Ivanov G. Johnston W.J. Kerr A. Kohler G. Knox K. Lawrie R.E. Lee W. Lewis B. Lin W.J.S. Lockley E. López‐Torres K. Lv S. Maddocks B.J. Marsh A. Mendiola V. Mirabello C.S. Miranda P.L. Norcott D. O'Hagan A.M. Olaru S.I. Pascu P.J. Rayner D. Read K. Ridge T. Ritter I. Roberts N. Samuri S. Sarpaki D. Somers R. Taylor T. Tuttle J.R. Varcoe C.L. Willis 《Journal of labelled compounds & radiopharmaceuticals》2018,61(5):455-467
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Continuity of Care among People Experiencing Homelessness and Mental Illness: Does Community Follow‐up Reduce Rehospitalization? 下载免费PDF全文
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Elizabeth Vásquez Karine Sahakyan John A. Batsis Cassandra Germain Virend K. Somers Benjamin A. Shaw 《Ethnicity & health》2018,23(1):72-80
Aims: This study sought to determine whether the association between varying levels of physical activity (PA) and all-cause and cardiovascular mortality differ by race/ethnicity in older adults.Methods: The sample comprised 2520 women and 2398 men drawn from National Health and Nutrition Examination Survey III (1988–1994) aged?≥?60 years. We used the metabolic equivalent (MET) of self-reported PA levels to define activity groups (inactive: those who did not report any PA; active: those who reported 3–6 METs for ≥5 times/week or >6 METs, ≥3 times/week; insufficiently active: those meeting neither criteria). Racial/Ethnic differences were modeled using proportional hazard regression (HR) adjusting for age, education, smoking, diabetes, and hypertension.Results: Among those classified as inactive, Non-Hispanic Blacks (NHB) (HR: 0.72, 95% CI: 0.58–0.90) and Mexican Americans (HR: 0.59, 95%CI: 0.45–0.78) had a lower risk of all-cause mortality when compared to non-Hispanic Whites (NHW). Among those classified as insufficiently active, Mexican Americans (HR: 0.63, 95% CI: 0.51–0.77), but not NHB (HR: 0.81, (95% CI: 0.64–1.02) had a lower risk of all-cause mortality when compared to NHWs Similar results were observed for cardiovascular mortality.Conclusion: Overall, PA in the elderly (either insufficient or active) is associated with a lower all-cause mortality across all race/ethnic groups as compared to NHW. Further investigation, including studies with larger sample, is needed to address the health consequences of varying degrees of PA in ethnically diverse populations. 相似文献
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PE Sreedharan Namboothiri Sreehari Narayanan Nair Krishnan Vijayan VK Visweswaran 《Indian Journal of Orthopaedics》2014,48(2):220-222
We report a case of disseminated meningospondylodiscitis in an elderly diabetic patient caused by Fusarium oxysporum. As the clinical presentation was nonspecific, the diagnosis of the condition could only be arrived at after laboratory and imaging studies. The diagnosis of the condition requires a high index of suspicion. Patient underwent thorough surgical debridement along with a short course of variconazole and remained asymptomatic after 36 months of diagnosis. Fusarium is a large genus of filamentous fungi widely distributed in soil and in association with plants. It is known to cause local infections (nail, cornea) in healthy humans and disseminated infection only in the immunocompromised. 相似文献
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Alexander Dimitri Miras Anna Kamocka Darshan Patel Simon Dexter Ian Finlay James C. Hopkins Omar Khan Marcus Reddy Peter Sedman Peter Small Shaw Somers Suzie Cro Peter Walton Carel W. le Roux Richard Welbourn 《Surgery for obesity and related diseases》2018,14(7):1033-1040
Background
The National Bariatric Surgery Registry (NBSR) is the largest bespoke database in the field in the United Kingdom.Objectives
Our aim was to analyze the NBSR to determine whether the effects of obesity surgery on associated co-morbidities observed in small randomized controlled clinical trials could be replicated in a "real life" setting within U.K. healthcare.Setting
United Kingdom.Methods
All NBSR entries for operations between 2000 and 2015 with associated demographic and co-morbidity data were analyzed retrospectively.Results
A total of 50,782 entries were analyzed. The patients were predominantly female (78%) and white European with a mean age of 45 ± 11 years and a mean body mass index of 48 ± 8 kg/m2. Over 5 years of follow-up, statistically significant reductions in the prevalence of type 2 diabetes, hypertension, dyslipidemia, sleep apnea, asthma, functional impairment, arthritis, and gastroesophageal reflux disease were observed. The "remission" of these co-morbidities was evident 1 year postoperatively and reached a plateau 2 to 5 years after surgery. Obesity surgery was particularly effective on functional impairment and diabetes, almost doubling the proportion of patients able to climb 3 flights of stairs and halving the proportion of patients with diabetes related hyperglycemia compared with preoperatively. Surgery was safe with a morbidity of 3.1% and in-hospital mortality of .07% and a reduced median inpatient stay of 2 days, despite an increasingly sick patient population.Conclusions
Obesity surgery in the U.K. results not only in weight loss, but also in substantial improvements in obesity-related co-morbidities. Appropriate support and funding will help improve the quality of the NBSR data set even further, thus enabling its use to inform healthcare policy. 相似文献10.