首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   1692259篇
  免费   125209篇
  国内免费   4069篇
耳鼻咽喉   21855篇
儿科学   55778篇
妇产科学   46205篇
基础医学   240636篇
口腔科学   48901篇
临床医学   150362篇
内科学   331836篇
皮肤病学   38840篇
神经病学   130886篇
特种医学   64083篇
外国民族医学   244篇
外科学   257413篇
综合类   39821篇
一般理论   533篇
预防医学   123835篇
眼科学   40352篇
药学   123958篇
  13篇
中国医学   4683篇
肿瘤学   101303篇
  2019年   13554篇
  2018年   20019篇
  2017年   15355篇
  2016年   16713篇
  2015年   19173篇
  2014年   26640篇
  2013年   38451篇
  2012年   53531篇
  2011年   56266篇
  2010年   33260篇
  2009年   31019篇
  2008年   52101篇
  2007年   55364篇
  2006年   55738篇
  2005年   53073篇
  2004年   51183篇
  2003年   48531篇
  2002年   46722篇
  2001年   92021篇
  2000年   93802篇
  1999年   76892篇
  1998年   18881篇
  1997年   16356篇
  1996年   16505篇
  1995年   16718篇
  1994年   15276篇
  1993年   14047篇
  1992年   57422篇
  1991年   55338篇
  1990年   53013篇
  1989年   50808篇
  1988年   46180篇
  1987年   44977篇
  1986年   42246篇
  1985年   40019篇
  1984年   29337篇
  1983年   24865篇
  1982年   13852篇
  1981年   12334篇
  1979年   25478篇
  1978年   17531篇
  1977年   14852篇
  1976年   13807篇
  1975年   14495篇
  1974年   17587篇
  1973年   16896篇
  1972年   15645篇
  1971年   14432篇
  1970年   13414篇
  1969年   12495篇
排序方式: 共有10000条查询结果,搜索用时 18 毫秒
1.
2.
3.
Modified-release opioids are often prescribed for the management of moderate to severe acute pain following total hip and knee arthroplasty, despite recommendations against their use due to increasing concerns regarding harm. The primary objective of this multicentre study was to examine the impact of modified-release opioid use on the incidence of opioid-related adverse events compared with immediate-release opioid use, among adult inpatients following total hip or knee arthroplasty. Data for total hip and knee arthroplasty inpatients receiving an opioid analgesic for postoperative analgesia during hospitalisation were collected from electronic medical records of three tertiary metropolitan hospitals in Australia. The primary outcome was the incidence of opioid-related adverse events during hospital admission. Patients who received modified with or without immediate-release opioids were matched to those receiving immediate-release opioids only (1:1) using nearest neighbour propensity score matching with patient and clinical characteristics as covariates. This included total opioid dose received. In the matched cohorts, patients given modified-release opioids (n = 347) experienced a higher incidence of opioid-related adverse events overall, compared with those given immediate-release opioids only (20.5%, 71/347 vs. 12.7%, 44/347; difference in proportions 7.8% [95%CI 2.3–13.3%]). Modified-release opioid use was associated with an increased risk of harm when used for acute pain during hospitalisation after total hip or knee arthroplasty.  相似文献   
4.
5.
目的 开展养老机构志愿者预立医疗照护计划培训并评价其效果。方法 应用基于Bloom目标教学理论构建的养老机构志愿者预立医疗照护计划培训内容,结合《预立医疗照护计划》知识教育手册、《我的五个愿望》手册、案例视频等教具,通过角色扮演、案例讨论等方式对53名养老机构志愿者进行培训。培训前后使用养老机构志愿者预立医疗照护计划知信行及自我效能问卷对志愿者进行调查,根据志愿者角色扮演表现评价其预立医疗照护计划沟通技能。结果 培训前后志愿者预立医疗照护计划认知、态度、行为意愿及自我效能差异有统计学意义(P<0.05,P<0.01),培训后75.47%志愿者预立医疗照护计划沟通技能达合格及以上水平。结论 预立医疗照护计划培训能改善养老机构志愿者的预立医疗照护计划知信行及自我效能感,培养其预立医疗照护计划沟通能力。  相似文献   
6.
Pharmaceutical Research - The quality testing and approval procedure for most pharmaceutical products is a streamlined process with standardized procedures for the determination of critical quality...  相似文献   
7.
Renal cell cancer (RCC) represents 2%-3% of all adulthood cancers and is the most common malignant neoplasm of the kidney (90%). In the mid-nineties of the last century, the standard of treatment for patients with metastatic RCC was cytokines. Sunititib and pazopanib were registered in 2007 and 2009, respectively, and have since been the standard first-line treatment for metastatic clear cell RCC (mccRCC). Renal cell cancer is a highly immunogenic tumor with tumor infiltrating cells, including CD8+ T lymphocytes, dendritic cells, natural killer cells (NK) and macrophages. This observation led to the design of new clinical trials in which patients were treated with immunotherapy. With the growing evidence that proangiogenic factors can have immunomodulatory effects on the host’s immune system, the idea of combining angiogenic drugs with immunotherapy has emerged, and new clinical trials have been designed. In the last few years, several therapeutic options have been approved [immunotherapy and immunotherapy/tyrosine kinase inhibitors (TKI)] for the first-line treatment of mccRCC. Nivolumab/ipilimumab is approved for the treatment of patients with intermediate and poor prognoses. Several checkpoint inhibitors (pembrolizumab, nivolumab, avelumab) in combination with TKI (axitinib, lenvatinib, cabozantinib) are approved for the treatment of patients regardless of their International mRCC Database Consortium prognostic group and PD-L1 expression. There is no specific and ideal biomarker that could help in selecting the ideal patient for the appropriate first-line treatment.  相似文献   
8.
Neuroscience and Behavioral Physiology - We present here results from analysis of the formation of brain bioelectrical activity in children and adolescents living in the northern region of Russia...  相似文献   
9.
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号