首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   24篇
  免费   10篇
  国内免费   2篇
耳鼻咽喉   2篇
妇产科学   9篇
基础医学   3篇
口腔科学   1篇
内科学   2篇
皮肤病学   3篇
外科学   4篇
综合类   1篇
预防医学   3篇
眼科学   1篇
药学   4篇
中国医学   3篇
  2017年   2篇
  2013年   4篇
  2012年   2篇
  2011年   3篇
  2010年   1篇
  2009年   12篇
  2008年   1篇
  2006年   1篇
  2005年   1篇
  2000年   1篇
  1998年   2篇
  1997年   2篇
  1996年   1篇
  1994年   2篇
  1987年   1篇
排序方式: 共有36条查询结果,搜索用时 15 毫秒
1.
2.
3.
探讨儿童青少年血中胰岛素、瘦素、脂联素和抵抗素水平与肥胖程度的关系。 方法 选择2004年北京市儿童青少年代谢综合征(BCAMS)调查总样本中的3511例(男1790例,女1721例) 6~18岁儿童青少年为研究对象,依据体重指数值分类标准将所有研究对象分为正常体重组1626例、超重组655例和肥胖组1230例。利用酶联免疫吸附试验法(ELISA)检测研究对象空腹血脂肪细胞因子水平。采用协方差分析比较超重组、肥胖组与正常体重组间脂肪细胞因子的差异;不同肥胖程度对预测脂肪细胞因子异常的作用采用多因素Logistic回归分析。结果 超重、肥胖组儿童血中胰岛素、瘦素水平高于正常体重组,并随着肥胖程度的增加而升高,且具有明显的男女性别差异;脂联素水平则随着肥胖程度的增加而降低;抵抗素水平仅见肥胖组与正常体重组儿童比较差异有统计学意义。采用多因素Logistic回归模型调整年龄、性别和青春发育期,以正常体重组为参照,进行对比分析。结论 儿童青少年血中胰岛素、瘦素、脂联素水平与肥胖程度密切相关,脂肪细胞因子异常检出率随着体重的增加而升高,因此,在儿童青少年时期控制体重、降低肥胖程度对预防“儿童成人慢性病”至关重要。  相似文献   
4.
5.
Different doses of hepatitis B virus vaccine—prepared by Korea Green Cross Corporation, were given to healthy infants born to HBsAg-negative mothers at birth, 1 and 6 months of age. A dose of 2 μg was administered intradermally in Group A and, in the three other groups, the vaccine was given intramuscularly (i.m.). An adequate follow-up observation was possible for 9 months after birth in 22, 25, 23 and 21 infants in Groups A, B, C and D, respecvely.
Group C (5 μg, i.m.) produced seroconversion most rapidly, showing the highest rate (96%) at 9 months of age. The lowest seroconversion rate (5%) was found at the age of 1 month in Group A subjects, but the rate increased to 91% after a booster dose was given at 6 months of age.
While it can be concluded that a 5 μg i.m. dose of vaccine at 0, 1 and 6 months of age is optimum for the immunization of infants in efficacy and economy, a 2 μg intradermal dose can also be considered as an immunogenic and economical regimen, though the immune response is slower and a special technique is required for immunization.  相似文献   
6.
 目的 探讨用旋转细胞培养系统(RCCS)进行大动物软骨细胞扩增的可行性。方法 将单层培养的具有正常表型的中国山羊软骨细胞和Cytodex-3微载体放入RCCS的培养容器中,加入DMEM 培养基进行培养。在细胞培养的第3、6、9、12 天,于倒置显微镜下观察Cytodex-3微载体表面软骨细胞生长形态及增殖变化情况,并对收获的软骨细胞进行蕃红花"O"染色和Ⅰ、Ⅱ型胶原免疫组织化学染色分析。结果 软骨细胞贴附于微载体表面生长,细胞初期呈球形、半球形凸起,逐渐向周围伸展,随时间的延长,贴附于微载体的细胞逐渐增多。收获的软骨细胞蕃红花"O"染色呈强阳性,Ⅰ型胶原染色呈阴性,Ⅱ型胶原染色则呈强阳性。结论 利用RCCS可简便快速地在体外扩增羊软骨细胞,培养的软骨细胞具有正常的表型,能特异性分泌软骨组织特有的基质成分。  相似文献   
7.
Aim: Catheter‐related infection is a major cause of catheter loss in peritoneal dialysis (PD). We evaluated the effect of catheter revision on the treatment of intractable exit site infection (ESI)/tunnel infection (TI) in PD patients who required catheter removal. Methods: We reviewed the medical records of 764 continuous ambulatory peritoneal dialysis (CAPD) patients from May 1995 to April 2011 at our hospital. One hundred and twenty six patients had more than one occurrence of ESI. Catheter revision was performed to treat intractable ESI/TI. Incidence of ESI, causative organisms and the outcomes of catheter revision were analyzed. Results: The total PD duration of all patients was 32 581 months. Three hundred and twelve ESI episodes occurred in 126 patients and the incidence of ESI was 1/104 patient‐months (0.12/patient‐year). The most common causative organism was methicillin‐sensitive Staphylococcus aureus (MSSA) (98 episodes), followed by Pseudomonas aeruginosa (63 episodes) and methicillin‐resistant S. aureus (MRSA) (28 episodes). Among these, catheter revision was required due to intractable ESI/TI in 36 patients. The most common causative organism was MSSA (14 episodes) followed by P. aeruginosa (10 episodes) and MRSA (six episodes) in catheter revision cases. The outcomes of catheter revision were as follows: ESI relapsed in 11 patients (30.6%) after catheter revision. Among them, five patients were treated with antibiotic treatment, two patients required secondary catheter revision, four patients required catheter removal due to ESI/TI accompanying peritonitis. The catheter survival rate after catheter revision was 89.7% in one year. There were no statistical differences in the rates of ESI relapse after catheter revision between ESI caused by P. aeruginosa (5/10, 50%) and ESI caused by S. aureus (6/21, 28.6%). Conclusion: Catheter revision may be an alternative treatment option to treat intractable ESI/TI before catheter removal is considered in PD patients.  相似文献   
8.
9.
Abstract: Rhabomyomatous mesenchymal hamartoma (RMH) is a rare hamartomatous lesion in the dermis and subcutaneous tissue. We report a case of solitary RMH occurring on the vagina of a newborn infant.  相似文献   
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号