全文获取类型
收费全文 | 3122篇 |
免费 | 199篇 |
国内免费 | 77篇 |
专业分类
耳鼻咽喉 | 12篇 |
儿科学 | 192篇 |
妇产科学 | 37篇 |
基础医学 | 360篇 |
口腔科学 | 65篇 |
临床医学 | 377篇 |
内科学 | 612篇 |
皮肤病学 | 83篇 |
神经病学 | 119篇 |
特种医学 | 411篇 |
外科学 | 208篇 |
综合类 | 170篇 |
一般理论 | 1篇 |
预防医学 | 421篇 |
眼科学 | 22篇 |
药学 | 156篇 |
2篇 | |
中国医学 | 4篇 |
肿瘤学 | 146篇 |
出版年
2023年 | 11篇 |
2021年 | 17篇 |
2020年 | 23篇 |
2019年 | 32篇 |
2018年 | 56篇 |
2017年 | 39篇 |
2016年 | 34篇 |
2015年 | 62篇 |
2014年 | 70篇 |
2013年 | 100篇 |
2012年 | 86篇 |
2011年 | 111篇 |
2010年 | 120篇 |
2009年 | 121篇 |
2008年 | 96篇 |
2007年 | 144篇 |
2006年 | 106篇 |
2005年 | 95篇 |
2004年 | 74篇 |
2003年 | 80篇 |
2002年 | 74篇 |
2001年 | 91篇 |
2000年 | 64篇 |
1999年 | 101篇 |
1998年 | 221篇 |
1997年 | 194篇 |
1996年 | 141篇 |
1995年 | 115篇 |
1994年 | 125篇 |
1993年 | 103篇 |
1992年 | 40篇 |
1991年 | 49篇 |
1990年 | 43篇 |
1989年 | 59篇 |
1988年 | 57篇 |
1987年 | 51篇 |
1986年 | 56篇 |
1985年 | 49篇 |
1984年 | 31篇 |
1983年 | 25篇 |
1982年 | 27篇 |
1981年 | 37篇 |
1980年 | 26篇 |
1979年 | 11篇 |
1978年 | 11篇 |
1977年 | 24篇 |
1976年 | 30篇 |
1975年 | 17篇 |
1971年 | 7篇 |
1970年 | 5篇 |
排序方式: 共有3398条查询结果,搜索用时 31 毫秒
1.
Hendrickx Gaelle De Roeck Veronique Russet Frdrick Dieleman Gwen Franic Tomislav Maras Athanasios McNicholas Fiona Paul Moli Santosh Paramala Schulze Ulrike Signorini Giulia Singh Swaran P. Street Cathy Tuomainen Helena Verhulst Frank Wolke Dieter Purper-Ouakil Diane Tremmery Sabine 《European child & adolescent psychiatry》2020,29(1):41-49
European Child & Adolescent Psychiatry - The majority of adolescents with mental health problems do not experience continuity of care when they reach the transition boundary of their child and... 相似文献
2.
Stokes Cara M. Alonso Jordi Andrade Laura Helena Atwoli Lukoye Cardoso Graça Chiu Wai Tat Dinolova Rumyana V. Gureje Oye Karam Aimee N. Karam Elie G. Kessler Ronald C. Chatterji Somnath King Andrew Lee Sing Mneimneh Zeina Oladeji Bibilola D. Petukhova Maria Rapsey Charlene Sampson Nancy A. Scott Kate Street Amy Viana Maria Carmen Williams Michelle A. Bossarte Robert M. 《Social psychiatry and psychiatric epidemiology》2020,55(3):393-405
Social Psychiatry and Psychiatric Epidemiology - Intimate partner violence (IPV) is a pervasive public health problem. Existing research has focused on reports from victims and few studies have... 相似文献
3.
4.
Traumatic Brain Injury and Suicidal Ideation Among U.S. Operation Enduring Freedom and Operation Iraqi Freedom Veterans 下载免费PDF全文
Jaimie L. Gradus Blair E. Wisco Matthew T. Luciano Katherine M. Iverson Brian P. Marx Amy E. Street 《Journal of traumatic stress》2015,28(4):361-365
Traumatic brain injury (TBI) is associated with suicidal behavior among veterans, and gender differences in the strength of associations may exist. Almost all research has been limited to Veterans Health Administration (VHA) patients, and it is unclear if findings generalize to veterans who do not use VHA services. We examined gender‐ and VHA‐user‐specific associations between TBI related to deployment and postdeployment suicidal ideation in a U.S. national sample of 1,041 female and 880 male Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) veterans. Path analysis was used to estimate TBI and suicidal ideation association, and examine PTSD and depression symptomatology in these associations. TBI was associated with suicidal ideation among male VHA users, OR = 3.64, 95% CI [2.21, 6.01]; and male and female nonusers, OR = 2.24, 95% CI [1.14, 4.44] and OR = 2.65, 95% CI [1.26, 5.58], respectively, in unadjusted analyses. This association was explained by depression symptoms among male and female nonusers. Among male VHA users an association between TBI and suicidal ideation remained when accounting for depression symptoms, OR = 2.50, 95% CI [1.33, 4.71]. Our findings offered evidence of an association between TBI and suicidal ideation among male OEF/OIF VHA users. 相似文献
5.
Recent Sexual Trauma and Adverse Health and Occupational Outcomes Among U.S. Service Women 下载免费PDF全文
Jeffrey Millegan Emma K. Milburn Cynthia A. LeardMann Amy E. Street Diane Williams Daniel W. Trone Nancy F. Crum‐Cianflone 《Journal of traumatic stress》2015,28(4):298-306
Sexual trauma is prevalent among military women, but data on potential effects are needed. The association of sexual trauma with health and occupational outcomes was investigated using longitudinal data from the Millennium Cohort Study. Of 13,001 U.S. service women, 1,364 (10.5%) reported recent sexual harassment and 374 (2.9%) recent sexual assault. Women reporting recent sexual harassment or assault were more likely to report poorer mental health: OR = 1.96, 95% CI [1.71, 2.25], and OR = 3.45, 95% CI [2.67, 4.44], respectively. They reported poorer physical health: OR = 1.39, 95% CI [1.20, 1.62], and OR = 1.39, 95% CI [1.04, 1.85], respectively. They reported difficulties in work/activities due to emotional health: OR = 1.80, 95% CI [1.59, 2.04], and OR = 2.70, 95% CI [2.12, 3.44], respectively. They also reported difficulties with physical health: OR = 1.55, 95% CI [1.37, 1.75], and OR = 1.52 95% CI [1.20, 1.91], respectively, after adjustment for demographic, military, health, and prior sexual trauma characteristics. Recent sexual harassment was associated with demotion, OR = 1.47, 95% CI [1.12, 1.93]. Findings demonstrated that sexual trauma represents a potential threat to military operational readiness and draws attention to the importance of prevention strategies and services to reduce the burden of sexual trauma on military victims. 相似文献
6.
Aetiological factors for oral manifestations of HIV 总被引:2,自引:0,他引:2
GD Palmer PG Robinson SJ Challacombe W Birnbaum D Croser PL Erridge T Hodgson D Lewis A McLaren JM Zakrzewska 《Oral diseases》1996,2(3):193-197
OBJECTIVES: Describe the oral diseases in HIV-infected individuals in London, UK and identify social and medical factors related to the presence of specific oral diseases.
DESIGN: Cross-sectional analytic study.
SETTING: Dental clinics.
SUBJECTS: Consecutive sample of 456 patients with HIV infection.
METHODS: Social and medical history and clinical examinations. Univariate and logistic regression analysis.
OUTCOMES: Presence of HIV-associated oral disease.
RESULTS: 80% of patients with AIDS and 50% of patients with HIV had a specific oral disease. The most common diseases were hairy leukoplakia (30%), erythematous candidiasis (24%), pseudomembranous candidiasis (14%), angular chielitis (6%), necrotising periodontal disease (8%) and non-recurrent ulceration (6%).
CONCLUSIONS: The presence of erythematous candidiasis was not related to advanced HIV disease. Pseudomembranous candidiasis, hairy leukoplakia and mucosal ulceration were significantly associated with advanced HIV disease. Smoking was also identified as a strong aetiological factor in oral diseases. Longitudinal studies are required to further explore the prognostic significance of oral diseases in HIV infection. 相似文献
DESIGN: Cross-sectional analytic study.
SETTING: Dental clinics.
SUBJECTS: Consecutive sample of 456 patients with HIV infection.
METHODS: Social and medical history and clinical examinations. Univariate and logistic regression analysis.
OUTCOMES: Presence of HIV-associated oral disease.
RESULTS: 80% of patients with AIDS and 50% of patients with HIV had a specific oral disease. The most common diseases were hairy leukoplakia (30%), erythematous candidiasis (24%), pseudomembranous candidiasis (14%), angular chielitis (6%), necrotising periodontal disease (8%) and non-recurrent ulceration (6%).
CONCLUSIONS: The presence of erythematous candidiasis was not related to advanced HIV disease. Pseudomembranous candidiasis, hairy leukoplakia and mucosal ulceration were significantly associated with advanced HIV disease. Smoking was also identified as a strong aetiological factor in oral diseases. Longitudinal studies are required to further explore the prognostic significance of oral diseases in HIV infection. 相似文献
7.
Background: The use of ozone therapy in the treatment of dental caries is equivocal. The aim of this study was to use an in vitro model to determine the effects of prior ozone application to dentine on biofilm formation and to measure any associated reduction in bacteria viability. Methods: Twenty dentine discs were bonded to the bases of 5 mL polycarbonate screw top vials. Ten dentine discs were infused with ozone for 40 seconds, 10 samples remained untreated as a control. The vials were filled with nutrient medium, sterilized and placed into the outflow from a continuous chemostat culture of Streptococcus mutans and Lactobacillus acidophilus for four weeks. At the conclusion of the experiment bacterial growth was monitored by taking optical density readings of the growth medium in each vial and the outer surface of the dentine specimens were examined by scanning electron microscopy as shown by SEM analysis. Results: Ozone infusion prevented biofilm formation on all the treated samples while there was substantial biofilm present on the control specimens. While the average optical density of the control specimens was almost twice that of the ozone infused dentine (0.710 for the control with a SD of 0.288 and 0.446 for the ozonated samples with a SD of 0.371), the results were not significant (p > 0.05). Conclusions: This preliminary study has shown that the infusion of ozone into non‐carious dentine prevented biofilm formation in vitro from S. mutans and L. acidophilus over a four‐week period. The possibility exists that ozone treatment may alter the surface wettability of dentine through reaction with organic constituents. 相似文献
8.
GT Terézhalmy AR Biesbrock PA Walters JM Grender RD Bartizek 《International journal of dental hygiene》2008,6(4):321-327
Abstract: Aim: To compare plaque removal efficacy of Oral‐B CrossAction (CA) used for 1 min with an American Dental Association (ADA) manual toothbrush used for 2 or 5 min in an examiner‐blind, three‐treatment, six‐period crossover study. Materials and methods: After refraining from all oral hygiene procedures for 23–25 h, subjects were randomly assigned to one of nine possible six‐period (visit) treatment sequences. Plaque was assessed at baseline (Rustogi Modified Navy Plaque Index). Post‐brushing scores were recorded after brushing with a marketed dentifrice and the assigned toothbrush for the specified duration. The same procedure was followed at each of six subsequent visits. Clinical measurements were carried out by the same examiner. Results: Forty subjects completed the study. All three treatments effectively removed plaque from the whole mouth, along the gingival margin and from approximal surfaces. Whole mouth and gingival margin plaque removal scores with CA for 1 min did not differ significantly from scores with the ADA toothbrush used for 2 min. The ADA brush used for 5 min showed significantly greater whole mouth (P < 0.001) and gingival margin (P < 0.001) plaque reduction than the two other treatments. Approximal plaque removal scores did not differ between the three treatments. Conclusions: Efficient plaque removal can be achieved after 1 min of brushing with CA. The amount of plaque removed did not differ significantly from that achieved with the ADA brush after 2 min of brushing. Greater whole mouth and gingival margin plaque removal scores were seen with the ADA brush after 5 min. 相似文献
9.
JM Palefsky M-E Penaranda LT Pierik LA Lagenaur LA MacPhail D Greenspan JS Greenspan 《Oral diseases》1997,3(Z1):S171-S176
Hairy leukoplakia (HL) is a lesion found on the side of the tongue of immunocompromised individuals, including those with human immunodeficiency virus (HIV) infection. The lesion has unique histopathologic features and is characterised by high-level Epstein-Barr virus (EBV) replication, multiple EBV strains, and extensive inter-and intra-strain recombination. Expression of EBV genes spanning the entire viral life cycle from latency-associated genes to late, replicative genes has been detected in the lesion. HL thus provides a unique opportunity to study EBV expression in oral epithelium, and to study expression of novel EBV genes. We therefore constructed a cDNA library from an HL biopsy and detected expression of two genes not previously described in vivo: BMRF-2 and BDLF-3. Sequence analysis of the cDNAs revealed few amino acid changes from the B95-8 sequence. Expression of both genes was localized to the lower prickle cell layer of the tongue epithelium. BMRF-2 protein expression was primarily detected in the cell nuclei of the upper prickle cell layer. BDLF-3 protein expression was observed in the perinuclear space and Golgi compartment. The function of these proteins is currently under investigation. 相似文献
10.
Katherine Treiman Lauren McCormack Laura Wagner Nancy Roach Rebecca Moultrie Hannah Sanoff Carla Bann Richard L. Street Mahima Ashok Bryce B. Reeve 《Patient education and counseling》2018,101(9):1585-1593