首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   105842篇
  免费   8774篇
  国内免费   6225篇
耳鼻咽喉   1112篇
儿科学   1605篇
妇产科学   2314篇
基础医学   12512篇
口腔科学   1970篇
临床医学   14156篇
内科学   16905篇
皮肤病学   933篇
神经病学   5702篇
特种医学   3890篇
外国民族医学   43篇
外科学   11272篇
综合类   14832篇
现状与发展   23篇
一般理论   20篇
预防医学   6168篇
眼科学   2876篇
药学   10776篇
  56篇
中国医学   4822篇
肿瘤学   8854篇
  2024年   280篇
  2023年   1506篇
  2022年   3805篇
  2021年   4950篇
  2020年   3516篇
  2019年   3233篇
  2018年   3557篇
  2017年   2923篇
  2016年   2861篇
  2015年   4426篇
  2014年   5631篇
  2013年   5040篇
  2012年   7528篇
  2011年   8287篇
  2010年   5020篇
  2009年   3860篇
  2008年   5287篇
  2007年   5579篇
  2006年   5432篇
  2005年   5746篇
  2004年   3841篇
  2003年   3411篇
  2002年   3017篇
  2001年   2453篇
  2000年   2671篇
  1999年   2722篇
  1998年   1669篇
  1997年   1575篇
  1996年   1411篇
  1995年   1224篇
  1994年   1043篇
  1993年   699篇
  1992年   1007篇
  1991年   832篇
  1990年   707篇
  1989年   646篇
  1988年   629篇
  1987年   576篇
  1986年   447篇
  1985年   374篇
  1984年   227篇
  1983年   174篇
  1982年   110篇
  1981年   118篇
  1980年   113篇
  1979年   123篇
  1978年   65篇
  1977年   72篇
  1976年   70篇
  1975年   59篇
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
4.
5.
Major ursodeoxycholic acid (UDCA)-based therapies for primary biliary cirrhosis (PBC) include UDCA only, or combined with either methotrexate (MTX), corticosteroids (COT), colchicine (COC), or bezafibrate (BEF). As the optimum treatment regimen is unclear and warrants exploration, we aimed to compare these therapies in terms of patient mortality or liver transplantation (MOLT) and adverse events (AE).PubMed, the Cochrane Library, and Scopus were searched for randomized controlled trials up to August 31, 2014. We estimated the hazard ratios (HRs) for MOLT and odds ratios (ORs) for AE. A sensitivity analysis based on the dose of UDCA was also executed.Thirty-one eligible articles were included. Compared with COT plus UDCA, UDCA (HR 0.38, 95% confidence interval [CI] 0.09–1.39), BEF plus UDCA (HR 0.29, 95% CI 0.02–4.83), COC plus UDCA (HR 0.39, 95% CI 0.07–2.25), MTX plus UDCA (HR 0.28, 95% CI 0.05–1.63), or OBS (HR 0.49, 95% CI 0.11–2.01) all provided an increased risk of MOLT. With respect to drug AE profile, although not differing appreciably, BEF plus UDCA was associated with more AEs compared with UDCA (OR 3.16, 95% CI 0.59–20.67), COT plus UDCA (OR 2.27, 95% CI 0.15–33.36), COC plus UDCA (OR 1.00, 95% CI 0.09–12.16), MTX plus UDCA (OR 2.03, 95% CI 0.23–17.82), or OBS (OR 3.00, 95% CI 0.53–20.75). The results of sensitivity analyses were highly consistent with previous analyses.COT plus UDCA was the optimal UDCA-based regimen for both MOLT and AEs. BEF plus UDCA was most likely to cause AEs, whereas monotherapy with UDCA and coadministriation of COT plus UDCA appeared to be associated with the fewest AEs for PBC treatment.  相似文献   
6.
Patients with mechanic ankle instability experience increased tibiotalar and subtalar joint laxity. However, in vivo joint kinematics in functional ankle instability (FAI) patients and lateral ankle sprain (LAS) copers, especially during dynamic activities, are poorly understood. Ten FAI patients, 10 LAS copers, and 10 healthy controls were included in this study. A dual fluoroscopic imaging system was used to analyze the tibiotalar and subtalar joint kinematics during stair descent. Five key poses of stair descent were analyzed. Kinematic data from six degrees of freedom were calculated utilizing a solid modeling software. The range of motion and joint positions in each degree of freedom were compared among the three groups. The tibiotalar joints of FAI patients and LAS copers were significantly more inverted than those of healthy controls during the foot strike (p = 0.016, = 0.264). The subtalar joints of FAI patients were significantly more anteriorly translated (pose 2, p = 0.003, = 0.352; pose 3, p < 0.001, = 0.454; pose 4, p = 0.004, = 0.334), inverted (pose 4, p = 0.027, = 0.234; pose 5,p = 0.034, = 0.221), and externally rotated (pose 4, p = 0.037, = 0.217; pose 5; p = 0.004, = 0.331) than those of healthy controls during the mid‐stance and the heel off. The FAI patients showed excessive tibiotalar inversion and subtalar joint hypermobility during stair descent. Meanwhile, the LAS copers maintained subtalar joint stability, and only showed excessive tibiotalar inversion in foot strike. These data provide insight into the mechanisms behind the development of FAI after initial LAS. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 37:1860–1867, 2019  相似文献   
7.
8.
9.
Abstract

Background

Comorbidities are commonly seen in patients with coronavirus disease 2019 (COVID-19), but the clinical implication is not yet well-delineated. We aim to characterize the prevalence and clinical implications of comorbidities in patients with COVID-19.  相似文献   
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号