首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   432126篇
  免费   28745篇
  国内免费   4328篇
耳鼻咽喉   5945篇
儿科学   9248篇
妇产科学   11996篇
基础医学   59746篇
口腔科学   12770篇
临床医学   35514篇
内科学   87828篇
皮肤病学   9570篇
神经病学   30481篇
特种医学   16179篇
外国民族医学   88篇
外科学   68006篇
综合类   13866篇
一般理论   75篇
预防医学   20219篇
眼科学   10677篇
药学   35619篇
  17篇
中国医学   3759篇
肿瘤学   33596篇
  2021年   3667篇
  2020年   2748篇
  2019年   4059篇
  2018年   6070篇
  2017年   4706篇
  2016年   4817篇
  2015年   6091篇
  2014年   8365篇
  2013年   10528篇
  2012年   14560篇
  2011年   14620篇
  2010年   9005篇
  2009年   8313篇
  2008年   12793篇
  2007年   13612篇
  2006年   13374篇
  2005年   12201篇
  2004年   11435篇
  2003年   11057篇
  2002年   10382篇
  2001年   29497篇
  2000年   29783篇
  1999年   24478篇
  1998年   5458篇
  1997年   4443篇
  1996年   4020篇
  1995年   3803篇
  1994年   3397篇
  1993年   3042篇
  1992年   16524篇
  1991年   15190篇
  1990年   14504篇
  1989年   14289篇
  1988年   12875篇
  1987年   12383篇
  1986年   11369篇
  1985年   10560篇
  1984年   7099篇
  1983年   5765篇
  1982年   2816篇
  1979年   5650篇
  1978年   3477篇
  1977年   3047篇
  1975年   2716篇
  1974年   3143篇
  1973年   2931篇
  1972年   2887篇
  1971年   2826篇
  1970年   2552篇
  1969年   2570篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
Clinical Oral Investigations - To analyze differences in variation of orthodontic diagnostic measurements on lateral cephalograms reconstructed from ultra low dose-low dose (ULD-LD) cone beam...  相似文献   
3.
PurposeThis study aimed to describe the spectrum of cancers observed in Bloom Syndrome and the observed survival and age of first cancer diagnosis in Bloom syndrome as these are not well-defined.MethodsData from the Bloom Syndrome Registry (BSR) was used for this study. Cancer history, ages of first cancer diagnosis, and ages of death were compiled from the BSR and analyzed.ResultsAmong the 290 individuals in the BSR, 155 (53%) participants developed 251 malignant neoplasms; 100 (65%) were diagnosed with 1 malignancy, whereas the remaining 55 (35%) developed multiple malignancies. Of the 251 neoplasms, 83 (33%) were hematologic and 168 (67%) were solid tumors. Hematologic malignancies (leukemia and lymphoma) were more common than any of the solid tumors. The most commonly observed solid tumors were colorectal, breast, and oropharyngeal. The cumulative incidence of any malignancy by age 40 was 83%. The median survival for all participants in the BSR was 36.2 years. There were no significant differences in time to first cancer diagnosis or survival by genotype among the study participants.ConclusionWe describe the spectrum of cancers observed in Bloom syndrome and the observed survival and age of first cancer diagnosis in Bloom syndrome. We also highlight the significant differences in survival and age of diagnosis seen among different tumor types and genotypes.  相似文献   
4.
Whether the underlying mutations are homozygous, heterozygous, or co-inherited with other hemoglobinopathies, sickle cell disease is known to afflict the kidneys, leading to the clinical entity known as sickle cell nephropathy (SCN). Although common, SCN remains diagnostically elusive. Conventional studies performed in the context of renal disorders often fail to detect early stage SCN. This makes the quest for early diagnosis and treatment more challenging, and it increases the burden of chronic kidney disease-related morbidity among patients. Novel diagnostic tools have been employed to overcome this limitation. In this study, we discuss various biomarkers of SCN, including those employed in clinical practice and others recently identified in experimental settings, such as markers of vascular injury, endothelial dysfunction, tubulo-glomerular damage, and oxidative stress. These include kidney injury molecule-1, monocyte chemoattractant protein-1, N-acetyl-B-D-glucosaminidase, ceruloplasmin, orosomucoid, nephrin, and cation channels, among others. Furthermore, we explore the potential of novel biomarkers for refining diagnostic and therapeutic approaches and describe some obstacles that still need to be overcome. We highlight the importance of a collaborative approach to standardize the use of promising new biomarkers. Finally, we outline the limitations of conventional markers of renal damage as extensions of the pathogenic process occurring at the level of the organ and its functional subunits, with a discussion of the expected pattern of clinical and biochemical progression among patients with SCN.  相似文献   
5.
6.
7.
Bulletin of Experimental Biology and Medicine - We studied whether menthol can promote penetration of natamycin, a representative antifungal macrolide agent, through the cornea. Natamycin...  相似文献   
8.
9.
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号