Inflammopharmacology - The efficacy of the sulforaphane derivative JY4 was evaluated in acute and chronic mouse models of ulcerative colitis induced by dextran sodium sulfate. Oral administration... 相似文献
AIM:To summarize the data of epidemiological studies on cataract prevalence over 50 years old in urban and rural areas of China from 2000 to 2020,and to analyze the prevalence of cataract and operation rate in China.METHODS:By searching Pub Med,EMBASE,Web of Science,Wanfang Data and CNKI,Chinese and English literatures on the prevalence of cataract in China were retrieved,and the relevant characteristic data were extracted.Then,Stata v15 SE software was used for Metaanalysis and heterogeneity test.According to the results of heterogeneity,the corresponding effect models were selected to combine the extracted data.RESULTS:A total of 20 studies were included in this study,with a total of 111434 cases.Meta-analysis showed heterogeneity.According to the random effect model,the overall prevalence of cataract in Chinese people over 50 years old was 27.45%,that in rural was 28.79%,and that in urban was 26.66%.The overall coverage rate of cataract surgery was 9.19%.CONCLUSION:The prevalence of cataract is high in China,and there is still room for improvement in surgical coverage,so it is very important to promote cataract screening and prevention. 相似文献
目的 探讨儿童哮喘风险评分(PARS)和哮喘预测指数(API)对反复喘息幼儿发生支气管哮喘(哮喘)的预测价值,为儿童哮喘的精准预测提供充分的证据。方法 收集100例1~3岁反复喘息儿童的临床资料,分别进行PARS和API评估,随访观察患儿是否发生哮喘,比较两者单独或联合应用的预测效能。结果 PARS预测反复喘息幼儿发生哮喘的灵敏度和特异度分别为54.55%和86.52%,ROC AUC为0.744 (95% CI 0.578~0.909)。API预测反复喘息幼儿发生哮喘的灵敏度和特异度分别为72.73%和52.81%,ROC曲线下面积为0.628(95% CI 0.460~0.796)。两者联合预测反复喘息幼儿发生哮喘的灵敏度和特异度分别为81.82%和44.94%,ROC曲线下面积为0.634(95% CI 0.474~0.794)。PARS预测反复喘息幼儿发生哮喘的ROC AUC略高于API及联合检测,但组间比较差异均无统计学意义(P均>0.05)。结论 PARS和API用于预测反复喘息幼儿发生哮喘的临床价值相当。 相似文献
Clinical and Experimental Medicine - Recently, the use of novel targeted drugs significantly improved the overall response rate (ORR) and survival of patients with relapsed/refractory chronic... 相似文献