血清 cf-DNA 定量分析在宫颈癌早期辅助诊断及预后判断中的价值

文章对宫颈癌、CINⅢ及健康妇女行血清cf-DNA定量检测，探讨血清cf-DNA定量分析诊断技术在宫颈癌的早期诊断及判断宫颈癌预后的辅助作用。结果显示，宫颈癌患者血清cf-DNA含量显著高于CINⅢ患者和健康妇女，Ⅱ、Ⅲ期宫颈癌患者血清cf-DNA含量明显高于Ⅰ期患者；血清cf-DNA对于宫颈癌诊断的敏感性和特异性均高于传统肿瘤标志物。     

关节松动术治疗肩周炎的综合评定

目的　探讨关节松动术对肩周炎的疗效。方法　采用肩关节松动术治疗肩周炎 3 2例 ,同时用肩关节功能评价量表在治疗前后对肩关节疼痛、ROM、ADL、肌力及局部形态进行综合评定。结果　治愈 8例 ,显效 13例 ,好转 9例 ,无效 2例 ,有效率 93 .75 %;治疗后肩关节功能评定得分显著增加 (P <0 .0 0 1) ;以治疗后肩关节功能分值、治疗前后得分增加值为标准评定疗效并与临床疗效评定结果比较 ,差异无显着性 (P >0 .0 5 )。结论　关节松动术对肩周炎具有显着疗效 ,肩关节功能评价量表可作为肩周炎的康复评定     

周围性面神经麻痹的综合治疗(附335例临床分析)

<正> 周围性面神经麻痹一种常见多发病。我科选用了超短波、TDP和自我手法按摩,依据病情需要,部分患者加用药物等综合治疗,取得了满意的效果,现讨论分析如下: 资料和方法本组周围性面神经麻痹335例,男204例,女131例;年龄5～20岁24例,<30岁119例,<40岁65例,<50岁55例,>50岁72例;病程最短的半天,最长的5个月,大部分病人由神经内科转来,根据病史,病人耳内、乳突区、下颌角周围轻度疼痛;面部表情肌瘫痪,不能皱额,蹙口角下垂,并被牵向健侧;不能鼓腮,吹哨等症状,诊断不难。     

慢性腹泻临证举隅

慢性腹泻证系临床常见之病症,其病位虽在脾胃,但与肝肾功能失常有关,常以脾肾阳虚,肝气乘者多见.脾为后天之本,主运化,但赖肾阳之温煦.肾阳不足易致脾阳失温,运化失司;脾阳不振运化不能,精微不充,气血化源不足,致精血亏损,久虚及肾,从而导致脾肾双虚,运化更失常态清浊相挟而生泄泻.临证可见大便时溏时泻,完谷不化,或五更肠鸣作泻,日久不愈反复发作.可伴脘腹不适或冷痛,食纳减少,或食后脘痞不舒,神疲乏力,肢寒畏冷,面色不泽,舌淡苔白脉沉缓少力.     

糖尿病并发低血钾63例原因分析

本文对63例糖尿病并发低血钾患者的治疗，发现良好的控制血糖、合并症，使血钾浓度的改变有统计学意义。初步分析糖尿病并发低血钾原因，现报道如下：     

Parkin基因启动子区-258T/G多态性与广西地区散发性帕金森病的相关性分析

Objective To investigate the association between the-258T/G polymorphism.in the pro-moter of parkin gene and the risk for sporadic parkinson's disease (SPD) in Guangxi Province, and in relationto the age of onset, of PD patients. Methods PCR-RFLP and sequence analysis were used to determine thegenotype of-258T/G polymorphism between all patients and healthy controls. Results The G allele was morecommon in patients than controls (55.20%:43.33% ,x2=6.898, P<0.05, OR=1.61, 95% CI: 1.13 ～2.30). The frequency of GG genotype was higher in patients than in controls (28.00 %: 18.33%, x2=7.159, P<0.05, OR=2.75, 95% CI : 1.31 ～ 5.77). The frequency of TG + GG genotype was higher in pa-tients than in controls (82.40%:68.33%, x2=6.551, P<0.05, OR=2.17.95%CI: 1.20 ～3.93). Afterbeing stratified by onset age, the frequencies of the G allele and GG genotype were significantly higher in pa-tients with onset age over 50 years than those in controls respectively. On the other hand, the frequency was notsignificantly different between the younger onset PD patients and the controls. Conclusion The parkin promot-er-258T/G polymorphism might be a risk factor for PD in Guangxi Province, and the G allele was increasedwith increasing age.     

Parkin基因启动子区-258T/G多态性与广西地区散发性帕金森病的相关性分析

Objective To investigate the association between the-258T/G polymorphism.in the pro-moter of parkin gene and the risk for sporadic parkinson's disease (SPD) in Guangxi Province, and in relationto the age of onset, of PD patients. Methods PCR-RFLP and sequence analysis were used to determine thegenotype of-258T/G polymorphism between all patients and healthy controls. Results The G allele was morecommon in patients than controls (55.20%:43.33% ,x2=6.898, P<0.05, OR=1.61, 95% CI: 1.13 ～2.30). The frequency of GG genotype was higher in patients than in controls (28.00 %: 18.33%, x2=7.159, P<0.05, OR=2.75, 95% CI : 1.31 ～ 5.77). The frequency of TG + GG genotype was higher in pa-tients than in controls (82.40%:68.33%, x2=6.551, P<0.05, OR=2.17.95%CI: 1.20 ～3.93). Afterbeing stratified by onset age, the frequencies of the G allele and GG genotype were significantly higher in pa-tients with onset age over 50 years than those in controls respectively. On the other hand, the frequency was notsignificantly different between the younger onset PD patients and the controls. Conclusion The parkin promot-er-258T/G polymorphism might be a risk factor for PD in Guangxi Province, and the G allele was increasedwith increasing age.     

吴茱萸汤方证学研究

采用病案调查的方法，从方证学角度对吴茱萸汤进行研究探讨，通过150例病案分析，探寻吴茱萸汤证的一般发病规律，主症、副症、舌脉分布规律，以及临证药物配伍、用法用量等规律，通过这些规律的探索，为临床正确使用该方提供参考依据。     

《伤寒论》“阳去入阴”辨析

归纳分析古今医家对《伤寒论》“阳去入阴”一语的不同认识，即“表邪传里说”、“邪传阳明说”、“邪传少阴说”及“入传三阴说”。结合该条该句的所处环境，经过综合归纳，层层剖析，提出“阳去入阴”应理解为“离开少阳，传人少阴或厥阴”的观点。