降压冲剂的药剂学研究

降压冲剂由钩藤、汉防己、罗布麻三味药组成。文章介绍了降压冲剂的生产工艺;以及成品的鉴别试验。并选择了汉防己甲素作为定量指标,控制其含量。     

家庭关系、劳动强度对女性月经规律的影响分析

目的:分析泸州市女性家庭关系及劳动强度对其月经情况的影响,进一步了解女性月经规律的影响因素。方法:采用自行设计的问卷对泸州市30~50岁女性的一般情况、月经史、婚姻史等进行调查。结果:调查对象的月经不规律发生率为20.95%,月经不规律发生率存在城乡差异,且有随其平常体力劳动强度增加而增加的趋势,女性月经不规律的发生率有随其家庭关系的和谐程度升高而降低的趋势。结论:泸州市女性月经不规律发生率较高,情绪状态、体力劳动等心理、社会因素对女性月经规律有影响,对经期女性加强关心、减少劳动负担有利于促进其身心健康。     

分叶剜除法在双极等离子体前列腺腔内剜除术中的应用

目的探讨分叶剜除法在双极等离子体前列腺腔内剜除中应用的价值。方法对92例需行前列腺增生手术的患者,在行双极等离子体腔内剜除术的过程中,加以应用分叶剜除法,观察手术的时间、术中并发症的出现情况。结果所有利用分叶法行前列腺腔内剜除术的患者手术均顺利完成,手术时间均控制在2h以内。有2例患者,只行单叶的剜除,拔出尿管后均不影响排尿,尿流率测定大于10ml/s。结论对于初学者而言,利用分叶剜除法行双极等离子体前列腺腔内剜除术,既可以保证手术安全及疗效,又可以缩短前列腺剜除术学习周期。     

Clinical Pathologic Study on Effect of Qianggan Capsule (强肝胶囊) in Treating Patients of Chronic Hepatitis B with Liver Cirrhosis

Objective: To explore the clinical therapeutic effect of Qianggan Capsule (QGC) in treating chronic hepatitis B with liver fibrosis from the pathological aspect. Methods: Sixty-three patients of chronic hepatitis B with liver fibrosis were randomly divided into the treated group (n=45) and the control group (n=18). Both groups were treated with general liver protective drugs, such as Glucurone and vitamins B complex for 6 months. To the treated group, QGC was used additionally. The levels of serum alanine transaminase and liver fibrosis indexes including hyaluronic acid (HA), collagen type Ⅳ (C-Ⅳ) and laminin (LN) as well as the pathological examination of liver biopsy were observed before and after treatment. Results: The liver cirrhosis indexes, HA, C-Ⅳ and LN, were improved significantly in the treated group after treatment, P<0.05. The liver function improvement rate in the treated group and the control group was 90.3% and 66.7% respectively, comparison of the two groups showed insignificant difference, P>0.05. Pathological examination showed that the effective rate of treatment on liver inflammatory necrosis activity grade in the treated group was 57.8% and that on liver fibrosis stage was 75.6%, which were significantly improved as compared with those before treatment (P<0.05 and P<0.01), while in the control group, no significant improvement was found after treatment (P>0.05). Conclusion: QGC has marked effects in reversing liver fibrosis and alleviating hepatic inflammatory necrosis in patients of chronic hepatitis B with liver fibrosis, and could lower the serum liver fibrosis related indexes effectively.     

双胶膏免疫调节作用的实验研究

运用淋巴细胞体外培养技术观察双胶膏的免疫作用．结果显示其能刺激T细胞有丝分裂，使T细胞增殖，对B细胞无作用。应用“氢考”造成的免疫抑制动物模型进行双胶膏对免疫功能影响实验，表明其对“氢考”造成的白细胞、血红蛋白量下降有一定的复原作用；能提高“氢考”模型小鼠的Th、Ts细胞百分率；一定程度地抵抗胸腺萎缩．     

痹痛灵胶囊治疗风湿性关节炎

目的 探讨痹痛灵胶囊抗风湿镇痛的临床效果。方法 56例活动期风湿性关节炎患者采用痹痛灵胶囊治疗，并作治疗前后对照研究。结果 主要症状、体征如关节疼痛指数、功能障碍指数、关节肿胀指数、双手握力、15m距离行走时间等均较治疗前明显改善（P＜0．01）；各项理化指标如ESR，ASO，IgG,IgA与治疗前相比有明显的好转（P＜0．01）。总有效率为100％。副作用轻微。结论 痹痛灵胶囊对风湿性关节炎有明显疗效，无明显副作用。     

参附青注射液对休克大鼠血压、心脏血液动力学和肠系膜微循环的影响

采用内毒素休克和心源性休克大鼠模型，观察参附青注射液对血压、心肌收缩力、肠系膜微循环的影响。结果表明，该方对内毒素休克大鼠上述指标有明显改善而仅改变心源性休克大鼠的微循环。     

参附青注射液对休克大鼠血压、心脏血液动力学和肠系膜微循环的影响

采用内毒素休克和心源性休克大鼠模型，观察参附青注射液对血压、心肌收缩力、肠系膜微循环的影响。结果表明，该方对内毒素休克大鼠上述指标有明显改善，而仅改变心源性休克大鼠的微循环     

经皮肾镜与输尿管软镜取石术治疗复杂性输尿管上段结石疗效观察

目的:观察分析研究经皮肾镜与输尿管软镜取石术治疗复杂性输尿管上段结石的疗效及安全性。方法:选择2016年2月至2018年2月东莞市第五人民医院收治的复杂性输尿管上段结石患者进行研究,采用回顾性分析方法,其中46例采用经皮肾镜方法治疗为肾镜组,50例采用输尿管软镜治疗者为输尿管软镜组,对比两组患者的手术情况及术后并发症。结果:肾镜组患者的手术成功率明显升高,但是治疗时间及手术后住院时间均长于输尿管软镜组,差异具有统计学意义(P0.05);肾镜组患者在手术后结石的清除率均高于输尿管软镜组,差异具有统计学意义(P0.05)。两组患者并发症发生情况比较,差异无统计学意义(P0.05)。结论:对复杂性输尿管上段结石患者给予经皮肾镜取石的结石清除效果好,输尿管软镜治疗的手术创伤小,两者各有利弊,需要根据患者实际情况进行合理选择。