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De La Rocha A Sucato DJ Tulchin K Podeszwa DA 《Clinical orthopaedics and related research》2012,470(9):2583-2590
Background
Although the success of the Bernese periacetabular osteotomy (PAO) has been reported for primary dysplasia, there is no study analyzing the radiographic, functional, and gait results of the PAO to correct residual hip dysplasia after previous pelvic surgery. 相似文献4.
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Richard E. McCarthy Daniel Sucato Joseph L. Turner Hong Zhang MeLeah A. W. Henson Kathryn McCarthy 《Clinical orthopaedics and related research》2010,468(3):705-710
There are few good surgical options that allow for continued spinal growth in patients with early-onset scoliosis. The “Shilla”
is a growth guidance system that does not require repeated surgical lengthenings. The Shilla system guides growth at the ends
of dual rods with the apex of the curve corrected, fused, and fixed to the rods. The growth occurs through the extraperiosteally
implanted pedicle screws that slide along the rods at either end of the construct. We implanted 11 2-month-old immature goats
with the dual rod system and euthanized all 11 goats 6 months postoperatively. We evaluated plain radiographs, regular computed
tomography, microcomputed tomography, physical and histologic examinations, and a microscopic wear analysis. All of the goat
spines grew with the implants in place; growth occurred in both the thoracic and lumbar ends of the rods for a total average
of 48 mm. None of the implants failed, although we observed minor wear at the rod/screw interface. Growth guidance with the
Shilla rod system allowed for continued growth in this goat model. 相似文献
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H J Allen C Karakousis M S Piver M Gamarra H Nava B Forsyth B Matecki A Jazayeri D Sucato E Kisailus 《Tumour biology》1987,8(4):218-229
Lactose-inhibitable lectin activity has been analyzed by hemagglutination assay in a variety of human tissues and cells obtained at surgery and autopsy. The lectin activity was detected in surgically removed melanoma, sarcoma, colon carcinoma, breast carcinoma, adjacent non-malignant tissues, non-malignant tissues obtained at autopsy and in cells isolated from malignant effusions. Although, on average, malignant tissue had a higher hemagglutinating titer than non-malignant tissue, similar tissues from different individuals varied widely in their apparent lectin content. The lectin was isolated from lung by affinity chromatography and was found to have a native molecular mass of 31,000 daltons and a subunit molecular mass of 14,000 daltons. Utilizing rabbit anti-lung lectin serum in an immunohistochemical assay, the lectin was found to be distributed throughout the cytoplasm of lung epithelial cells. Ouchterlony immunodiffusion analysis confirmed the presence of this lectin in a variety of tissues and in some body fluids. In vitro metabolic radiolabelling experiments showed that the presence of lectin in tissues was most likely due to endogenous synthesis rather than absorption from body fluids. Lectin isolated from several tissues was found to bind to human buffy coat cell receptors. 相似文献
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Amy L. Herrick Michael P. Marshal Helen A. Smith Gina Sucato Ron D. Stall 《The Journal of adolescent health》2011,48(3):306-309
BackgroundThe social marginalization and victimization experienced by sexual minority youth (SMY) may lead to increased risk behaviors and higher rates of negative health outcomes compared with their heterosexual peers.MethodsWe conducted a meta-analysis to examine whether SMY reported higher rates of sex while intoxicated. Studies that report rates of substance use during sex in both SMY and heterosexual youth and had a mean participant age of 18 or less were included in our meta-analysis. Effect sizes were extracted from six studies (nine independent data sets and 24 effect sizes) that met study criteria and had high inter-rater reliability (.98).ResultsResults indicated that SMY were almost twice as likely to report sex while intoxicated as compared with heterosexual peers. A random-effects meta-analysis showed a moderate ([overall weighted effect OR] = 1.91, p < .0001) weighted effect size for the relationship between sexual orientation and the use of drugs at the time of sexual intercourse, with the mean effect size for each study ranging from 1.21 to 3.50 and individual effect sizes ranging from .35 to 9.86.DiscussionOur findings highlight the need for healthcare providers to screen SMY for participation in substance use during sexual intercourse and to offer risk reduction counseling during office visits. 相似文献