全文获取类型
收费全文 | 3186篇 |
免费 | 319篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 19篇 |
儿科学 | 98篇 |
妇产科学 | 60篇 |
基础医学 | 469篇 |
口腔科学 | 45篇 |
临床医学 | 447篇 |
内科学 | 494篇 |
皮肤病学 | 54篇 |
神经病学 | 277篇 |
特种医学 | 116篇 |
外科学 | 400篇 |
综合类 | 75篇 |
一般理论 | 3篇 |
预防医学 | 403篇 |
眼科学 | 15篇 |
药学 | 237篇 |
肿瘤学 | 297篇 |
出版年
2023年 | 20篇 |
2021年 | 53篇 |
2020年 | 50篇 |
2019年 | 54篇 |
2018年 | 48篇 |
2017年 | 50篇 |
2016年 | 50篇 |
2015年 | 52篇 |
2014年 | 88篇 |
2013年 | 115篇 |
2012年 | 170篇 |
2011年 | 180篇 |
2010年 | 102篇 |
2009年 | 81篇 |
2008年 | 172篇 |
2007年 | 172篇 |
2006年 | 158篇 |
2005年 | 155篇 |
2004年 | 116篇 |
2003年 | 131篇 |
2002年 | 112篇 |
2001年 | 98篇 |
2000年 | 104篇 |
1999年 | 98篇 |
1998年 | 39篇 |
1997年 | 28篇 |
1996年 | 25篇 |
1995年 | 28篇 |
1994年 | 24篇 |
1993年 | 20篇 |
1992年 | 92篇 |
1991年 | 75篇 |
1990年 | 74篇 |
1989年 | 79篇 |
1988年 | 61篇 |
1987年 | 51篇 |
1986年 | 39篇 |
1985年 | 40篇 |
1984年 | 30篇 |
1983年 | 24篇 |
1982年 | 23篇 |
1981年 | 18篇 |
1979年 | 39篇 |
1977年 | 24篇 |
1976年 | 18篇 |
1975年 | 24篇 |
1974年 | 27篇 |
1973年 | 25篇 |
1970年 | 17篇 |
1967年 | 18篇 |
排序方式: 共有3509条查询结果,搜索用时 15 毫秒
1.
2.
Renuka V. Iyer MD Bhavana Konda MD MPH Christos Fountzilas MD Sarbajit Mukherjee MD MS Dwight Owen MD MS Kristopher Attwood PhD Chong Wang MA Orla Maguire PhD Hans Minderman PhD Sheryl-Ann Suffren BA Karen Hicks BS John Wilton PhD Robert Bies PhD Danielle Casucci BA Diane Reidy-Lagunes MD Manisha Shah MD 《Cancer》2020,126(16):3689-3697
3.
4.
5.
6.
7.
Divya J. Aickara MS Jeffrey McBride MD PhD Brian Morrison MD Paolo Romanelli MD 《Journal of cutaneous pathology》2020,47(4):398-401
Gastrointestinal stromal tumors (GISTs) are mesenchymal neoplasms which account for less than 1% of all gastrointestinal malignancies. Of all the extra-abdominal metastases of GIST, superficial soft tissue metastases are the rarest. Previous reports have found success with sunitinib in imatinib-resistant GIST, but we report a certain wild-type KIT mutation GIST with cutaneous and subcutaneous metastasis that was unresponsive to multiple tyrosine kinase inhibitor (TKI) treatments. This case illustrates that knowing the specific type of KIT mutations may uncover resistance of certain GIST's to TKIs, necessitating more targeted and alternative therapy. 相似文献
8.
9.
10.
Acute skin toxicity in adjuvant breast radiation can be reduced with modern radiotherapy (RT) techniques. However, having reviewed the literature, we found no dosimetric constraint for acute skin toxicity that would be applicable to modern RT planning. This study aimed to identify dosimetric factors that are associated with higher rates of acute skin toxicity. A retrospective review was carried out including women who received adjuvant forward-planned intensity-modulated radiotherapy (IMRT) after breast-conserving surgery. Acute skin toxicity grade was prospectively recorded. A total of 131 patients were analyzed. On multivariate analysis, the V105%?>?30?cc (p?=?0.013) and the use of conventional fractionation (CF) (p?=?0.001) were statistically significant for acute skin toxicity. On literature review, current quantitative dosimetric parameters that have shown statistical significance include a V107%?>?3?cc in hypofractionation (HF), V107%?>?9?cc in CF, treated volume 110%?>?5.13%, and V107%?>?28.6%. There is little evidence on the predictive value of clinically applicable dosimetric factors in acute skin toxicity. Given the recent improvements in RT planning, we would consider a V107% or a V110% too high a dosimetric value to be useful for the majority of patients. We have shown that a V105% of greater than 30?cc is significantly associated with acute skin toxicity, controlling for other variables. We suggest that this is currently the most useful modifiable parameter available to reduce skin toxicity and is applicable to modern RT planning. We also suggest that consideration be given to hypofractionated schedules to further reduce acute skin toxicity. 相似文献