全文获取类型
收费全文 | 2532篇 |
免费 | 326篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 102篇 |
妇产科学 | 35篇 |
基础医学 | 350篇 |
口腔科学 | 33篇 |
临床医学 | 296篇 |
内科学 | 631篇 |
皮肤病学 | 47篇 |
神经病学 | 169篇 |
特种医学 | 102篇 |
外科学 | 390篇 |
综合类 | 108篇 |
现状与发展 | 20篇 |
一般理论 | 5篇 |
预防医学 | 271篇 |
眼科学 | 34篇 |
药学 | 154篇 |
中国医学 | 3篇 |
肿瘤学 | 111篇 |
出版年
2023年 | 50篇 |
2021年 | 41篇 |
2020年 | 37篇 |
2019年 | 32篇 |
2018年 | 73篇 |
2017年 | 63篇 |
2016年 | 58篇 |
2015年 | 69篇 |
2014年 | 86篇 |
2013年 | 122篇 |
2012年 | 112篇 |
2011年 | 124篇 |
2010年 | 94篇 |
2009年 | 100篇 |
2008年 | 110篇 |
2007年 | 92篇 |
2006年 | 113篇 |
2005年 | 79篇 |
2004年 | 95篇 |
2003年 | 93篇 |
2002年 | 75篇 |
2001年 | 80篇 |
2000年 | 70篇 |
1999年 | 65篇 |
1998年 | 49篇 |
1997年 | 55篇 |
1996年 | 60篇 |
1995年 | 46篇 |
1994年 | 29篇 |
1993年 | 34篇 |
1992年 | 56篇 |
1991年 | 49篇 |
1990年 | 49篇 |
1989年 | 51篇 |
1988年 | 44篇 |
1987年 | 50篇 |
1986年 | 38篇 |
1985年 | 44篇 |
1984年 | 41篇 |
1983年 | 29篇 |
1982年 | 31篇 |
1981年 | 14篇 |
1980年 | 10篇 |
1979年 | 15篇 |
1978年 | 22篇 |
1977年 | 10篇 |
1976年 | 11篇 |
1975年 | 14篇 |
1974年 | 10篇 |
1969年 | 8篇 |
排序方式: 共有2881条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
Aisha F. Badr Sawsan Kurdi Samah Alshehri Claire McManus Jeannie Lee 《Saudi Pharmaceutical Journal》2018,26(8):1204-1207
Background
Hospitalization can contribute to insomnia in many patients and is usually treated symptomatically. However, sedative/hypnotic misuse is associated with complications in this population, especially in the elderly. Such complications include dizziness, falls and over-sedation. Due to the implicit dangers, widespread use of these drugs for insomnia, particularly in older patients, has been discouraged by many hospitals. The aim of this study was to review and evaluate prescribing patterns and to optimize the use of the sedative/hypnotic agents through daily pharmacy interventions at a community hospital.Methods
This was a biphasic before and after study. Data on sedative/hypnotic use was collected retrospectively for a 2-month period and a sample of 100 patients was randomly selected for analysis. A 2-month prospective phase followed, in which daily orders were reviewed by one pharmacy resident and recommendations made to discontinue any unnecessary, newly prescribed sedative/hypnotic orders when appropriate. Finally, results of both phases were compared for any differences in patient demographics, being prescribed more than one sedative/hypnotic, and complications documented.Results
During the prospective phase, pharmacist interventions led to the discontinuation of 25% of a total of 97 sedative/hypnotic orders in 97 patients. The number of patients receiving more than one sedative/hypnotic agents in the intervention group was significantly lower than the retrospective control group (15 Vs. 34, P?=?0.0026). The incidence of complications was not significantly different between the control and intervention groups for the following: over-sedation, falls and delirium (p?=?0.835, p?=?0.185, p?=?0.697, respectively).Conclusion
This study suggests that the use of sedative/hypnotics in the inpatient units (excluding the critical care unit), is somewhat prevalent, and many patients may be on more than one sedative/hypnotic, which could potentially cause cumulative harm. During the intervention phase, 25% of the total in-hospital orders for sedative/hypnotics were discontinued following recommendations made by a pharmacist, and significantly lower number of patients receiving duplicate sedative/hypnotics was noted. Further efforts should be implemented to avoid unnecessary sedative/hypnotic initiation in hospitalized patients, and to ensure monitoring by pharmacists is optimized. 相似文献5.
6.
Andrea K. Vaags PhD Sarah Bowdin BM MSc MRCPCH Mary‐Lou Smith PhD Brigitte Gilbert‐Dussardier MD Katja S. Brocke‐Holmefjord MD Katia Sinopoli PhD CPsych Cindy Gilles MSc Tove B. Haaland MD Catherine Vincent‐Delorme MD Emmanuelle Lagrue MD Radu Harbuz MD Susan Walker PhD Christian R. Marshall PhD Gunnar Houge MD PhD Vera M. Kalscheuer PhD Stephen W. Scherer PhD Berge A. Minassian MD 《Annals of neurology》2014,76(5):758-764
Synaptic function is central to brain function. Understanding the synapse is aided by studies of patients lacking individual synaptic proteins. Common neurological diseases are genetically complex. Their understanding is likewise simplified by studies of less common monogenic forms. We detail the disease caused by absence of the synaptic protein CNKSR2 in 8 patients ranging from 6 to 62 years old. The disease is characterized by intellectual disability, attention problems, and abrupt lifelong language loss following a brief early childhood epilepsy with continuous spike‐waves in sleep. This study describes the phenotype of CNKSR2 deficiency and its involvement in systems underlying common neurological disorders. Ann Neurol 2014;76:758–764 相似文献
7.
Meredith Achey BM Jason L. Aldred MD Noha Aljehani MD Bastiaan R. Bloem MD PhD Kevin M. Biglan MD MPH Piu Chan MD PhD Esther Cubo MD PhD E. Ray Dorsey MD MBA Christopher G. Goetz MD Mark Guttman MD Anhar Hassan MB BCh FRACP Suketu M. Khandhar MD Zoltan Mari MD Meredith Spindler MD Caroline M. Tanner MD PhD Pieter van den Haak MSc Richard Walker MD Jayne R. Wilkinson MD 《Movement disorders》2014,29(7):871-883
Travel distance, growing disability, and uneven distribution of doctors limit access to care for most Parkinson's disease (PD) patients worldwide. Telemedicine, the use of telecommunications technology to deliver care at a distance, can help overcome these barriers. In this report, we describe the past, present, and likely future applications of telemedicine to PD. Historically, telemedicine has relied on expensive equipment to connect single patients to a specialist in pilot programs in wealthy nations. As the cost of video conferencing has plummeted, these efforts have expanded in scale and scope, now reaching larger parts of the world and extending the focus from care to training of remote providers. Policy, especially limited reimbursement, currently hinders the growth and adoption of these new care models. As these policies change and technology advances and spreads, the following will likely develop: integrated care networks that connect patients to a wide range of providers; education programs that support patients and health care providers; and new research applications that include remote monitoring and remote visits. Together, these developments will enable more individuals with PD to connect to care, increase access to expertise for patients and providers, and allow more‐extensive, less‐expensive participation in research. © 2014 International Parkinson and Movement Disorder Society 相似文献
8.
9.
The restructuring of emergency healthcare services has led to more blunt thoracic trauma being treated by a multidisciplinary team, including general, orthopaedic and trauma surgeons, often without immediate access to a thoracic surgeon. Having a critical mass of injured patients in a central location, it has been possible to bring expertise from other areas of intensive care, radiology and surgery and apply new technology and techniques to the trauma patient. We now see the regular use of endovascular stenting and embolization reducing the need for urgent surgery on unstable patients and the increasing use of extracorporeal membranous oxygenation (ECMO) to salvage patients with acute respiratory distress syndrome. A more liberal use of video-assisted thoracic surgery (thoracoscopic) decortication and chest wall fixation both reduce ICU requirements and shorten hospital stay. It is hoped that these improvements in the hospital management of chest injuries will not only improve survival, but that the reduction in the late sequelae of chronic pain and loss of stamina will translate into improved return-to-work rates. 相似文献
10.