全文获取类型
收费全文 | 26466篇 |
免费 | 1616篇 |
国内免费 | 364篇 |
专业分类
耳鼻咽喉 | 519篇 |
儿科学 | 261篇 |
妇产科学 | 483篇 |
基础医学 | 4306篇 |
口腔科学 | 519篇 |
临床医学 | 2035篇 |
内科学 | 5282篇 |
皮肤病学 | 1103篇 |
神经病学 | 1723篇 |
特种医学 | 1853篇 |
外科学 | 3441篇 |
综合类 | 84篇 |
一般理论 | 9篇 |
预防医学 | 775篇 |
眼科学 | 507篇 |
药学 | 2851篇 |
中国医学 | 439篇 |
肿瘤学 | 2256篇 |
出版年
2024年 | 11篇 |
2023年 | 220篇 |
2022年 | 731篇 |
2021年 | 1136篇 |
2020年 | 533篇 |
2019年 | 739篇 |
2018年 | 902篇 |
2017年 | 745篇 |
2016年 | 1130篇 |
2015年 | 1610篇 |
2014年 | 1728篇 |
2013年 | 1880篇 |
2012年 | 2845篇 |
2011年 | 2609篇 |
2010年 | 1612篇 |
2009年 | 1247篇 |
2008年 | 1622篇 |
2007年 | 1444篇 |
2006年 | 1298篇 |
2005年 | 1161篇 |
2004年 | 854篇 |
2003年 | 732篇 |
2002年 | 602篇 |
2001年 | 204篇 |
2000年 | 171篇 |
1999年 | 136篇 |
1998年 | 85篇 |
1997年 | 66篇 |
1996年 | 44篇 |
1995年 | 32篇 |
1994年 | 41篇 |
1993年 | 26篇 |
1992年 | 25篇 |
1991年 | 39篇 |
1990年 | 21篇 |
1989年 | 20篇 |
1988年 | 24篇 |
1987年 | 20篇 |
1986年 | 16篇 |
1985年 | 9篇 |
1984年 | 14篇 |
1982年 | 7篇 |
1981年 | 9篇 |
1979年 | 5篇 |
1978年 | 4篇 |
1976年 | 5篇 |
1974年 | 4篇 |
1972年 | 4篇 |
1969年 | 4篇 |
1966年 | 3篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
Chang Y Jung Hyo S Choi Jin S Ju Hyo S Park Tae G Kwon Yong C Bae Dong K Ahn 《The journal of pain》2006,7(10):747-756
The present study investigated the role of central metabotropic glutamate receptors (mGluRs) in interleukin-1beta (IL-1beta)-induced mechanical allodynia and mirror-image mechanical allodynia in the orofacial area. Experiments were carried out on male Sprague-Dawley rats weighing 230 to 280 g. After administration of 0.01, 0.1, 1, or 10 pg of IL-1beta into a subcutaneous area of the vibrissa pad, we examined the withdrawal behavioral responses produced by 10 successive trials of an air-puff ramp pressure applied ipsilaterally or contralaterally to the IL-1beta injection site. Subcutaneous injection of IL-1beta produced mechanical allodynia and mirror-image mechanical allodynia in the orofacial area. Intracisternal administration of CPCCOEt, a mGluR1 antagonist, or MPEP, a mGluR5 antagonist, reduced IL-1beta-induced mechanical allodynia and mirror-image mechanical allodynia. Intracisternal administration of APDC, a group II mGluR agonist, or L-AP4, a group III mGluR agonist, reduced both IL-1beta-induced mechanical allodynia and mirror-image mechanical allodynia. The antiallodynic effect, induced by APDC or L-AP4, was blocked by intracisternal pretreatment with LY341495, a group II mGluR antagonist, or CPPG, a group III mGluR antagonist. These results suggest that groups I, II, and III mGluRs differentially modulated IL-1beta-induced mechanical allodynia, as well as mirror-image mechanical allodynia, in the orofacial area. PERSPECTIVE: Central group I mGluR antagonists and groups II and III mGluR agonists modulate IL-1beta-induced mechanical allodynia and mirror-image mechanical allodynia in the orofacial area. Therefore, the central application of group I mGluR antagonists or groups II and III mGluR agonists might be of therapeutic value in treating pain disorder. 相似文献
4.
5.
6.
7.
Hyun Jik Kim Jinna Kim Joo-Heon Yoon 《European archives of oto-rhino-laryngology》2006,263(8):778-782
Olfactory neuroblastoma is a rare, malignant neoplasm arising from the olfactory epithelium. It has an aggressive biological behavior that is characterized by local recurrence, atypical distant metastasis, and poor long-term prognosis. The incidence of cervical lymph node metastasis in olfactory neuroblastoma is variable, and treatment modalities are controversial. Moreover, few reports have been published concerning retropharyngeal lymph node metastasis from olfactory neuroblastoma. We present two cases of olfactory neuroblastoma with retropharyngeal lymph node metastasis. In addition, we provided a review of the current literature regarding olfactory neuroblastoma and retropharyngeal lymph node metastasis from olfactory neuroblastoma. 相似文献
8.
Duk Hyun Sung Joon Young Choi Du-Hwan Kim Eun-Sang Kim Young-Ik Son Young-Seok Cho Su Jin Lee Kyung-Han Lee Byung-Tae Kim 《Journal of nuclear medicine》2007,48(11):1790-1795
The purpose of this study was to investigate whether (18)F-FDG PET/CT is useful for localizing dystonic cervical muscles in patients with idiopathic cervical dystonia (ICD) by comparing disease severity before and disease severity after botulinum toxin (BT) injection into hypermetabolic muscles. METHODS: Six patients with ICD underwent (18)F-FDG PET/CT. Dystonic muscles suitable for BT injection therapy were defined as those showing diffusely increased (18)F-FDG uptake. RESULTS: Hypermetabolic cervical muscles were identified in all 6 patients. In 2 patients who underwent PET/CT both in a supine position and in a sitting position during (18)F-FDG uptake, abnormal hypermetabolic muscles were observed by PET/CT only when patients were in the sitting position with their heads and necks in the adopted abnormal involuntary posture. Symptoms were significantly improved in 4 patients who underwent BT injection therapy guided by PET/CT and who were clinically monitored. CONCLUSION: (18)F-FDG PET/CT is potentially useful for identifying dystonic cervical muscles for BT therapy in patients with ICD. 相似文献
9.
This study examined the effects of cognitive-behavioral group therapy (CBT) on the self-esteem, depression, and self-efficacy of runaway adolescents residing in a shelter in Seoul, South Korea. The study used a control group pretest-posttest design. The experimental group and the control group consisted of 14 and 13 male subjects, respectively, with subjects having been randomly assigned to these groups. The experimental group participated in a CBT that consisted of eight sessions over an 8-week period; the control group did not participate in the program. To examine the effects of the CBT on dependent variables, the Wilcoxon signed rank test was used. The scores on depression decreased significantly (z = -2.325, p = .02) and those on self-efficacy increased significantly (z = -2.098, p = .03) after the intervention in the experimental group. There was no significant change on self-esteem (z = -1.19, p = .23). In the control group, the scores on depression, self-esteem, and self-efficacy did not change significantly after the intervention period. The CBT developed in this study consisted of structured and specific content that could be usefully applied to runaway adolescents residing in a shelter. 相似文献
10.