全文获取类型
| 收费全文 | 4254篇 |
| 免费 | 257篇 |
| 国内免费 | 64篇 |
专业分类
| 耳鼻咽喉 | 94篇 |
| 儿科学 | 70篇 |
| 妇产科学 | 59篇 |
| 基础医学 | 697篇 |
| 口腔科学 | 36篇 |
| 临床医学 | 368篇 |
| 内科学 | 1003篇 |
| 皮肤病学 | 91篇 |
| 神经病学 | 178篇 |
| 特种医学 | 224篇 |
| 外科学 | 559篇 |
| 综合类 | 30篇 |
| 预防医学 | 186篇 |
| 眼科学 | 66篇 |
| 药学 | 513篇 |
| 中国医学 | 62篇 |
| 肿瘤学 | 339篇 |
出版年
| 2023年 | 11篇 |
| 2022年 | 13篇 |
| 2021年 | 96篇 |
| 2020年 | 65篇 |
| 2019年 | 95篇 |
| 2018年 | 119篇 |
| 2017年 | 94篇 |
| 2016年 | 151篇 |
| 2015年 | 185篇 |
| 2014年 | 268篇 |
| 2013年 | 285篇 |
| 2012年 | 442篇 |
| 2011年 | 432篇 |
| 2010年 | 273篇 |
| 2009年 | 222篇 |
| 2008年 | 295篇 |
| 2007年 | 306篇 |
| 2006年 | 244篇 |
| 2005年 | 244篇 |
| 2004年 | 206篇 |
| 2003年 | 163篇 |
| 2002年 | 152篇 |
| 2001年 | 28篇 |
| 2000年 | 20篇 |
| 1999年 | 15篇 |
| 1998年 | 19篇 |
| 1997年 | 15篇 |
| 1996年 | 10篇 |
| 1995年 | 8篇 |
| 1994年 | 9篇 |
| 1993年 | 9篇 |
| 1992年 | 2篇 |
| 1991年 | 5篇 |
| 1990年 | 4篇 |
| 1989年 | 3篇 |
| 1988年 | 7篇 |
| 1987年 | 4篇 |
| 1986年 | 3篇 |
| 1985年 | 8篇 |
| 1984年 | 5篇 |
| 1983年 | 3篇 |
| 1982年 | 5篇 |
| 1981年 | 4篇 |
| 1980年 | 4篇 |
| 1979年 | 4篇 |
| 1976年 | 2篇 |
| 1972年 | 2篇 |
| 1971年 | 7篇 |
| 1969年 | 3篇 |
| 1966年 | 1篇 |
排序方式： 共有4575条查询结果，搜索用时 203 毫秒
1.
2.
Caryn Wujanto Jeremy Tey David Chia Francis Ho Kiat Huat Ooi Alvin S. Wong Yu Yang Soon Keith Lim 《Journal of Geriatric Oncology》2019,10(2):292-297
Background
Muscle invasive bladder cancer (MIBC) is prevalent in the older patients, who are a vulnerable population with multiple co-morbidities and at increased risk of complications. Radical cystectomy is often not suitable, hence radical radiotherapy (RT) is an alternative option. We reviewed the outcomes of older patients treated with RT with or without concurrent chemotherapy (CRT) at our institution.Methods
We retrospectively reviewed patients aged 65?years and above treated with radical RT for MIBC at our institution between March 2002 to January 2017. Data was collected from institutional medical records and RT databases. The primary outcome was 2- and 5-year overall survival (OS), recurrence free survival (RFS), and toxicities. Univariate cox proportional hazard regression models were performed to identify independent factors with significant impact on survival.Results
We identified 45 patients (34 males, 11 females) with a median age of 77?years (range 65–95). All patients received maximal transurethral resection of the bladder tumour prior to RT. Median dose of total RT was 64?Gy (range 50–69.8?Gy). Twenty one patients (47%) received CRT. Planned treatment was completed in 42 (93.3%) patients. Median follow-up was 31?months (range 1–147?months). The 2- and 5-year OS was 64% and 44%, respectively. The 2- and 5-year RFS was 68% and 49%, respectively. Median RFS was 34?months (range 8–121?months). Median OS was 56?months (range 18–100?months). Univariate analysis showed that performance status (0–1 vs. 2–3; HR 2.7, 95% CI 1.07–6.8, p?=?0.035) and International Society of Geriatric Oncology (SIOG) group (≤2 vs. >2; HR 3.23, 95% CI 1.12–8.64, p?=?0.019) were significantly associated with increased hazard for death. One patient (2%) had grade 3 cystitis.Conclusion
Radical RT is well tolerated in older patients with MIBC. We report outcomes similar to published data. Older patients should be considered for curative treatment despite their age. However, careful selection is warranted as frail patients (PS ≥2; SIOG >2) may benefit less. 相似文献3.
4.
5.
6.
Kim Ah Rim Tak Young Ran Shin Yong Soon Yun E. Hwa Park Hyun-Kyung Lee Hyun Ju 《Maternal and child health journal》2020,24(5):601-611
Maternal and Child Health Journal - Maternal attachment to promote role development in mothers of preterm infants is critical for babies’ optimal growth and development. However, few models... 相似文献
7.
Rutenberg Michael S. Rotondo Ronny L. Rao Dinesh Holtzman Adam L. Indelicato Daniel J. Huh Soon Morris Christopher G. Mendenhall William M. 《Journal of neuro-oncology》2020,147(2):387-395
Journal of Neuro-Oncology - Craniopharyngioma is a benign tumor that commonly develops within the suprasellar region. The tumor and treatment can have debilitating consequences for pediatric and... 相似文献
8.
9.
10.