全文获取类型
收费全文 | 8562篇 |
免费 | 866篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 67篇 |
儿科学 | 213篇 |
妇产科学 | 195篇 |
基础医学 | 1088篇 |
口腔科学 | 139篇 |
临床医学 | 860篇 |
内科学 | 2004篇 |
皮肤病学 | 180篇 |
神经病学 | 750篇 |
特种医学 | 257篇 |
外科学 | 985篇 |
综合类 | 279篇 |
一般理论 | 7篇 |
预防医学 | 1084篇 |
眼科学 | 124篇 |
药学 | 488篇 |
1篇 | |
中国医学 | 4篇 |
肿瘤学 | 713篇 |
出版年
2021年 | 105篇 |
2020年 | 82篇 |
2019年 | 116篇 |
2018年 | 148篇 |
2017年 | 112篇 |
2016年 | 117篇 |
2015年 | 147篇 |
2014年 | 198篇 |
2013年 | 297篇 |
2012年 | 422篇 |
2011年 | 390篇 |
2010年 | 249篇 |
2009年 | 193篇 |
2008年 | 361篇 |
2007年 | 430篇 |
2006年 | 431篇 |
2005年 | 417篇 |
2004年 | 395篇 |
2003年 | 347篇 |
2002年 | 302篇 |
2001年 | 298篇 |
2000年 | 292篇 |
1999年 | 227篇 |
1998年 | 84篇 |
1997年 | 79篇 |
1996年 | 65篇 |
1995年 | 86篇 |
1994年 | 58篇 |
1993年 | 74篇 |
1992年 | 232篇 |
1991年 | 208篇 |
1990年 | 193篇 |
1989年 | 162篇 |
1988年 | 189篇 |
1987年 | 165篇 |
1986年 | 166篇 |
1985年 | 150篇 |
1984年 | 96篇 |
1983年 | 101篇 |
1982年 | 54篇 |
1981年 | 59篇 |
1979年 | 74篇 |
1978年 | 84篇 |
1976年 | 59篇 |
1975年 | 65篇 |
1974年 | 55篇 |
1973年 | 100篇 |
1972年 | 54篇 |
1971年 | 65篇 |
1970年 | 66篇 |
排序方式: 共有9438条查询结果,搜索用时 31 毫秒
1.
A. D. Kane J. Soar R. A. Armstrong E. Kursumovic M. T. Davies F. C. Oglesby L. Cortes C. Taylor I. K. Moppett S. Agarwal J. Cordingley J. Dorey S. J. Finney G. Kunst D. N. Lucas G. Nickols R. Mouton J. P. Nolan B. Patel V. J. Pappachan F. Plaat B. R. Scholefield J. H. Smith L. Varney T. M. Cook collaborators 《Anaesthesia》2023,78(6):701-711
Detailed contemporary knowledge of the characteristics of the surgical population, national anaesthetic workload, anaesthetic techniques and behaviours are essential to monitor productivity, inform policy and direct research themes. Every 3–4 years, the Royal College of Anaesthetists, as part of its National Audit Projects (NAP), performs a snapshot activity survey in all UK hospitals delivering anaesthesia, collecting patient-level encounter data from all cases under the care of an anaesthetist. During November 2021, as part of NAP7, anaesthetists recorded details of all cases undertaken over 4 days at their site through an online survey capturing anonymous patient characteristics and anaesthetic details. Of 416 hospital sites invited to participate, 352 (85%) completed the activity survey. From these, 24,177 reports were returned, of which 24,172 (99%) were included in the final dataset. The work patterns by day of the week, time of day and surgical specialty were similar to previous NAP activity surveys. However, in non-obstetric patients, between NAP5 (2013) and NAP7 (2021) activity surveys, the estimated median age of patients increased by 2.3 years from median (IQR) of 50.5 (28.4–69.1) to 52.8 (32.1–69.2) years. The median (IQR) BMI increased from 24.9 (21.5–29.5) to 26.7 (22.3–31.7) kg.m–2. The proportion of patients who scored as ASA physical status 1 decreased from 37% in NAP5 to 24% in NAP7. The use of total intravenous anaesthesia increased from 8% of general anaesthesia cases to 26% between NAP5 and NAP7. Some changes may reflect the impact of the COVID-19 pandemic on the anaesthetic population, though patients with confirmed COVID-19 accounted for only 149 (1%) cases. These data show a rising burden of age, obesity and comorbidity in patients requiring anaesthesia care, likely to impact UK peri-operative services significantly. 相似文献
2.
Luke D. Kim Elizabeth R. Pfoh Bo Hu Lei Kou Lisa M. Knowlton Kristan Staudenmayer Michael B. Rothberg 《Journal of the American Medical Directors Association》2019,20(9):1086-1090.e2
ObjectivesTo identify factors associated with 30-day all-cause readmission rates in surgical patients discharged to skilled nursing facilities (SNFs), and derive and validate a risk score.DesignRetrospective cohort.Setting and participantsPatients admitted to 1 tertiary hospital's surgical services between January 1, 2011, and December 31, 2014 and subsequently discharged to 110 SNFs within a 25-mile radius of the hospital. The first 2 years were used for the derivation set and the last 2 for validation.MethodsData were collected on 30-day all cause readmissions, patient demographics, procedure and surgical service, comorbidities, laboratory tests, and prior health care utilization. Multivariate regression was used to identify risk factors for readmission.ResultsDuring the study period, 2405 surgical patients were discharged to 110 SNFs, and 519 (21.6%) of these patients experienced readmission within 30 days. In a multivariable regression model, hospital length of stay [odds ratio (OR) per day: 1.03, 95% confidence interval (CI) 1.02-1.04], number of hospitalizations in past year (OR 1.24 per hospitalization, 95% CI 1.18-1.31), nonelective surgery (OR 1.33, 95% CI 1.18-1.65), low-risk service (orthopedic/spine service) (OR 0.32, 95% CI 0.25-0.42), and intermediate-risk service (cardiothoracic surgery/urology/gynecology/ear, nose, throat) (OR 0.69, 95% CI 0.53-0.88) were associated with all-cause readmissions. The model had a C index of 0.71 in the validation set. Using the following risk score [0.8 × (hospital length of stay) + 7 × (number of hospitalizations in past year) +10 for nonelective surgery, +36 for high-risk surgery, and +20 for intermediate-risk surgery], a score of >40 identified patients at high risk of 30-day readmission (35.8% vs 12.6%, P < .001).Conclusions/ImplicationsAmong surgical patients discharged to an SNF, a simple risk score with 4 parameters can accurately predict the risk of 30-day readmission. 相似文献
3.
Ashton A. Connor Robert E. Denroche Gun Ho Jang Mathieu Lemire Amy Zhang Michelle Chan-Seng-Yue Gavin Wilson Robert C. Grant Daniele Merico Ilinca Lungu John M.S. Bartlett Dianne Chadwick Sheng-Ben Liang Jenna Eagles Faridah Mbabaali Jessica K. Miller Paul Krzyzanowski Heather Armstrong Steven Gallinger 《Cancer cell》2019,35(2):267-282.e7
4.
5.
Jennifer A. Sumner Natalie L. Colich Monica Uddin Don Armstrong Katie A. McLaughlin 《Neuropsychopharmacology》2019,85(3):268-278
Background
Recent conceptual models argue that early life adversity (ELA) accelerates development, which may contribute to poor mental and physical health outcomes. Evidence for accelerated development in youths comes from studies of telomere shortening or advanced pubertal development following circumscribed ELA experiences and neuroimaging studies of circuits involved in emotional processing. It is unclear whether all ELA is associated with accelerated development across global metrics of biological aging or whether this pattern emerges following specific adversity types.Methods
In 247 children and adolescents 8 to 16 years of age with wide variability in ELA exposure, we evaluated the hypothesis that early environments characterized by threat, but not deprivation, would be associated with accelerated development across two global biological aging metrics: DNA methylation (DNAm) age and pubertal stage relative to chronological age. We also examined whether accelerated development explained associations of ELA with depressive symptoms and externalizing problems.Results
Exposure to threat-related ELA (e.g., violence) was associated with accelerated DNAm age and advanced pubertal stage, but exposure to deprivation (e.g., neglect, food insecurity) was not. In models including both ELA types, threat-related ELA was uniquely associated with accelerated DNAm age (β = .18) and advanced pubertal stage (β = .28), whereas deprivation was uniquely associated with delayed pubertal stage (β = ?.21). Older DNAm age was related to greater depressive symptoms, and a significant indirect effect of threat exposure on depressive symptoms was observed through DNAm age.Conclusions
Early threat-related experiences are particularly associated with accelerated biological aging in youths, which may be a mechanism linking ELA with depressive symptoms. 相似文献6.
7.
8.
Verbruggen Lisanne C. Hudson Melissa M. Bowers Daniel C. Ronckers Cécile M. Armstrong Gregory T. Skinner Roderick Hoving Eelco W. Janssens Geert O. van der Pal Helena J. H. Kremer Leontine C. M. Mulder Renée L. 《Journal of neuro-oncology》2020,147(2):417-425
Journal of Neuro-Oncology - Childhood, adolescent and young adult (CAYA) cancer survivors treated with cranial radiotherapy are at risk for developing subsequent meningiomas. There is insufficient... 相似文献
9.
10.