首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   27872篇
  免费   2528篇
  国内免费   68篇
耳鼻咽喉   302篇
儿科学   1102篇
妇产科学   588篇
基础医学   3543篇
口腔科学   432篇
临床医学   3472篇
内科学   4643篇
皮肤病学   511篇
神经病学   2768篇
特种医学   812篇
外国民族医学   1篇
外科学   3993篇
综合类   674篇
一般理论   23篇
预防医学   3327篇
眼科学   428篇
药学   2081篇
中国医学   44篇
肿瘤学   1724篇
  2023年   210篇
  2022年   143篇
  2021年   649篇
  2020年   431篇
  2019年   750篇
  2018年   871篇
  2017年   614篇
  2016年   593篇
  2015年   675篇
  2014年   939篇
  2013年   1327篇
  2012年   1896篇
  2011年   1950篇
  2010年   1086篇
  2009年   951篇
  2008年   1533篇
  2007年   1535篇
  2006年   1482篇
  2005年   1446篇
  2004年   1299篇
  2003年   1230篇
  2002年   1177篇
  2001年   649篇
  2000年   573篇
  1999年   480篇
  1998年   245篇
  1997年   209篇
  1996年   235篇
  1995年   187篇
  1994年   183篇
  1993年   160篇
  1992年   359篇
  1991年   347篇
  1990年   368篇
  1989年   335篇
  1988年   269篇
  1987年   288篇
  1986年   220篇
  1985年   258篇
  1984年   208篇
  1983年   161篇
  1982年   139篇
  1981年   112篇
  1980年   117篇
  1979年   169篇
  1978年   145篇
  1977年   109篇
  1974年   128篇
  1973年   110篇
  1969年   99篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
Access to and delivery of quality mental health services remains challenging in rural and remote Canada. To improve access, services, and support providers, improved understanding is needed about nurses who identify mental health as an area of practice. The aim of this study is to explore the characteristics and context of practice of registered nurses (RNs), licensed practical nurses (LPNs), and registered psychiatric nurses (RPNs) in rural and remote Canada, who provide care to those experiencing mental health concerns. Data were from a pan-Canadian cross-sectional survey of 3822 regulated nurses in rural and remote areas. Individual and work community characteristics, practice responsibilities, and workplace factors were analysed, along with responses to open-ended questions. Few nurses identified mental health as their sole area of practice, with the majority of those being RPNs employed in mental health or crisis centres, and general or psychiatric hospitals. Nurses who indicated that mental health was only one area of their practice were predominantly employed as generalists, often working in both hospital and primary care settings. Both groups experienced moderate levels of job resources and demands. Over half of the nurses, particularly LPNs, had recently experienced and/or witnessed violence. Persons with mental health concerns in rural and remote Canada often receive care from those for whom mental health nursing is only part of their everyday practice. Practice and education supports tailored for generalist nurses are, therefore, essential, especially to support nurses in smaller communities, those at risk of violence, and those distant from advanced referral centres.  相似文献   
4.
5.
Forensic Toxicology - We have developed and validated a high-sensitivity method to quantify lysergic acid diethylamide (LSD) and 2-oxo-3-hydroxy-LSD (OH-LSD) in oral fluid samples using...  相似文献   
6.
Journal of Thrombosis and Thrombolysis - Historically, treatment of heparin-induced thrombocytopenia (HIT) includes a non-heparin parenteral anticoagulant with bridging to warfarin once platelets...  相似文献   
7.
8.
BACKGROUNDTo understand the features of a replicating vaccine that might drive potent and durable immune responses to transgene-encoded antigens, we tested a replication-competent adenovirus type 4 encoding influenza virus H5 HA (Ad4-H5-Vtn) administered as an oral capsule or via tonsillar swab or nasal spray.METHODSViral shedding from the nose, mouth, and rectum was measured by PCR and culturing. H5-specific IgG and IgA antibodies were measured by bead array binding assays. Serum antibodies were measured by a pseudovirus entry inhibition, microneutralization, and HA inhibition assays.RESULTSAd4-H5-Vtn DNA was shed from most upper respiratory tract–immunized (URT-immunized) volunteers for 2 to 4 weeks, but cultured from only 60% of participants, with a median duration of 1 day. Ad4-H5-Vtn vaccination induced increases in H5-specific CD4+ and CD8+ T cells in the peripheral blood as well as increases in IgG and IgA in nasal, cervical, and rectal secretions. URT immunizations induced high levels of serum neutralizing antibodies (NAbs) against H5 that remained stable out to week 26. The duration of viral shedding correlated with the magnitude of the NAb response at week 26. Adverse events (AEs) were mild, and peak NAb titers were associated with overall AE frequency and duration. Serum NAb titers could be boosted to very high levels 2 to 5 years after Ad4-H5-Vtn vaccination with recombinant H5 or inactivated split H5N1 vaccine.CONCLUSIONReplicating Ad4 delivered to the URT caused prolonged exposure to antigen, drove durable systemic and mucosal immunity, and proved to be a promising platform for the induction of immunity against viral surface glycoprotein targets.TRIAL REGISTRATIONClinicalTrials.gov NCT01443936 and NCT01806909.FUNDINGIntramural and Extramural Research Programs of the NIAID, NIH (U19 AI109946) and the Centers of Excellence for Influenza Research and Surveillance (CEIRS), NIAID, NIH (contract HHSN272201400008C).  相似文献   
9.
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号