全文获取类型
收费全文 | 526篇 |
免费 | 34篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 25篇 |
儿科学 | 37篇 |
妇产科学 | 2篇 |
基础医学 | 39篇 |
口腔科学 | 26篇 |
临床医学 | 52篇 |
内科学 | 99篇 |
皮肤病学 | 5篇 |
神经病学 | 68篇 |
特种医学 | 15篇 |
外科学 | 142篇 |
综合类 | 4篇 |
预防医学 | 4篇 |
眼科学 | 21篇 |
药学 | 20篇 |
肿瘤学 | 4篇 |
出版年
2023年 | 6篇 |
2022年 | 10篇 |
2021年 | 33篇 |
2020年 | 20篇 |
2019年 | 27篇 |
2018年 | 36篇 |
2017年 | 18篇 |
2016年 | 25篇 |
2015年 | 37篇 |
2014年 | 35篇 |
2013年 | 39篇 |
2012年 | 57篇 |
2011年 | 45篇 |
2010年 | 19篇 |
2009年 | 21篇 |
2008年 | 26篇 |
2007年 | 26篇 |
2006年 | 20篇 |
2005年 | 26篇 |
2004年 | 15篇 |
2003年 | 14篇 |
2002年 | 8篇 |
排序方式: 共有563条查询结果,搜索用时 15 毫秒
1.
Emrah Aydn Heather Nolan Jose Luis Peir Patricia Burns Beth Rymeski Foong-Yen Lim 《Pediatric surgery international》2020,36(4):485-491
Primary closure is often inadequate for large congenital diaphragmatic hernia (CDH) and necessitates repair by prosthetic patch or autologous muscle flap. Our aim was to evaluate outcomes of open patch versus flap repair, specifically diaphragmatic reherniation. A retrospective review (IRB #2017-6361) was performed on all CDH patients repaired from 2005 to 2016 at a single academic children’s hospital. Patients were excluded from final analysis if they had primary or minimally invasive repair, expired, or were lost to follow-up. Of 171 patients, 151 (88.3%) survived to discharge, 9 expired after discharge and 11 were lost to follow up, leaving 131 (86.8%) long-term survivors. Median follow-up was 5 years. Open repair was performed in 119 (90.8%) of which 28 (23.5%) underwent primary repair, 34 (28.6%) patch repair, and 57 (47.9%) flap repair. Overall, 6/119 (5%) patients reherniated, 1/28 (3.6%) in the primary group, 3/34 (8.8%) in the patch group, and 2/57 (3.5%) in the flap group. Comparing prosthetic patch to muscle flap repair, there was no significant difference in the number of patients who recurred nor time to reherniation (3 vs. 2, p = 0.295; 5.5 ± 0.00 months vs. 53.75 ± 71.06 months, p = 0.288). One patient in the patch group recurred twice. Both muscle flap and patch repair of large CDH are feasible and durable with a relatively low risk of recurrence. 相似文献
2.
3.
Cem Yalin Kilinc Ahmet Emrah Acan Emre Gultac Rabia Mihriban Kilinc Onur Hapa Nevres Hurriyet Aydogan 《Acta orthopaedica et traumatologica turcica》2019,53(1):6-14
Objectives
The aim of this study was to evaluate the clinical and radiological results of the surgical treatment of acetabular fractures using modified Stoppa approach.Methods
A total of 57 patients (mean age 37.8 years; range 15–84) who underwent surgical treatment for acetabular fracture with modified Stoppa approach from February 2013 to June 2016 were included into the study. The mean follow-up time was 28.1 months (range 24–35). The records were reviewed for fracture patterns, time to surgery, operative time, blood loss, reduction quality, and perioperative complications. Reduction quality was graded as anatomic, imperfect, or poor. The Harris Hip Score (HHS) and Merle d'Aubigné score were used for functional evaluation.Results
Among the 63 acetabulum fractures of the 57 patients, 27 were associated with both columns, 12 were T-type fractures, 10 were transverse, 7 were anterior column/posterior hemitransverse, 5 were anterior column, and 2 were anterior wall fracture. A single surgeon performed all operations. Pfannenstiel incision was used in the first 19 cases while vertical midline incision in the remaining 38 cases. Average time to operation was 5.5 days, and supplemental lateral windows were used in 17 (29.8%) patients. Average blood loss and operation times were 660 mL and 152 min, respectively. Radiological outcomes were anatomic, imperfect, and poor in 52 (82.5%), 9 (14.2%), and 2 (3.2%) of the acetabulum fractures, respectively. Clinical outcomes at 2 years with HHS and Merle d’Aubigné scores were mean 86.6 (range 66–96) (Excellent in 27, good in 23, fair in 4, poor in 3 patient) and 16.7 (range 10–18) (Excellent in 25, very good in 18, good in 6, fair in 5, poor in 3 patient), respectively. There was a significant relation between the reduction quality and clinical outcome (p < 0.001), while there was no significant relation between the clinical outcome and the fracture type (p > 0.05). Iatrogenic external iliac vein damage was noted in 2 patients. Obturator nerve palsy was noted in 3 patients, who recovered spontaneously at mean time of 3.7 months (range 3–5). Rectus abdominus paralysis was noted in 2 of the 19 (10.5%) Pfannenstiel-incision patients but not in the vertical-incision patients.Conclusion
Our experience in 57 patients shows that satisfactory results can be obtained, even in bilateral fractures with vertical midline incision.Level of evidence
Level IV Therapeutic Study 相似文献4.
Balta Sabah Emirtekin Emrah Kircaburun Kagan Griffiths Mark D. 《International journal of mental health and addiction》2020,18(3):628-639
International Journal of Mental Health and Addiction - One of the relatively new negative consequences of smartphone use is “phubbing” (snubbing someone while an individual checks their... 相似文献
5.
6.
Fatih Mehmet Kandemir Cuneyt Caglayan Emrah Hicazi Aksu Serkan Yildirim Sefa Kucukler Cihan Gur Gizem Eser 《Andrologia》2020,52(3):e13524
This study investigated the effects of rutin against reproductive damage caused by toxic mercury in male rats. Thirty-five Sprague Dawley rats were used. Control group was injected with saline for 7 days. The rutin-100 group received 100 mg/kg/b.w. rutin for 7 days. Mercuric chloride (HgCl2) group received 1.23 mg/kg/b.w. of HgCl2 for 7 days. Mercury chloride + rutin-50 group received 50 mg/kg/b.w. rutin and HgCl2 1.23 mg/kg/b.w. for 7 days. HgCl2 + rutin-100 group received 100 mg/kg/b.w. rutin and HgCl2 1.23 mg/kg/b.w. for 7 days. It was detected that HgCl2 treatment increased malondialdehyde (MDA) levels, tumour necrosis factor-α (TNF-α) and cyclooxygenase-2 (COX-2) expressions, necrosis and degeneration of spermatogonium, dead and abnormal sperm percentages; tubular walls thinning; and decreased antioxidant enzyme activities and sperm motility. It was determined that rutin application reduced testicular damage caused by HgCl2. In conclusion, rutin administration may treat HgCl2 toxicity in testes. 相似文献
7.
8.
Study Type – Therapy (case series) Level of Evidence 4 What’s known on the subject? and What does the study add? This study reflects the second largest series of revascularization operations performed in different etiologic and risk groups with the longest follow up. Beyond that this is the only study in which CC‐EMG techniques were used preoperatively to exclude some patients and to predict postoperative success in penile revascularization.
OBJECTIVE
? To determine the overall long‐term success of penile revascularization surgery in the treatment of vasculogenic erectile dysfunction (ED) and also to investigate the effect of risk factors on the results of a modified Furlow–Fisher technique.PATIENTS AND METHODS
? Between 1999 and 2010, 125 men with a mean (sd , range) age of 43.2 (11.3, 23–69) years underwent penile revascularization surgery. In all, 110 men completed the long‐term follow‐up with a mean follow‐up of 73.2 months. ? Diagnostic evaluations, penile colour Doppler ultrasonography, corpus cavernosum electromyography, and cavernosometry, were performed in all the men before surgery. ? The efficacy of the surgery was assessed as improvement or failure according to the change in the five‐item version of the International Index of Erectile Function (IIEF‐5). A ≥5 point increase in the IIEF‐5 score during the latest patient visit after surgery compared with that before surgery was regarded as improvement (surgical success).RESULTS
? The mean (sd ) IIEF‐5 score was 7.3 (3.2) before surgery and at the end of the follow‐up periodit was 16.8 (3.1). ? The success rates were 81.8% at 3 months, 77.2% at 1 year, 70% at 2 years, 66.3% at 3 years and 63.6% at 5 years after surgery in the men who achieved a no‐ED threshold score of >26 in the IIEF‐15. ? The success rate was the highest in the men with no risk factors (92.8%). ? Seven patients (6.36%) showed signs of glans hypervascularization as a major complication.CONCLUSIONS
? Penile revascularization surgery has not been widely used by urologists probably due to the technical difficulties and the use of phosphodiesterase type 5 inhibitors. ? However, with reported high rates of noncompliance or failure of oral pharmacotherapy it seems likely that this surgery will become more popular in the near future. 相似文献9.
10.
Erdal Belen ?rfan ?ahin Bar?? Güng?r Burak Ay?a ?lhan ?lker Avc? Murat Av?ar Suleyman Sezai Y?ld?z Fatih Ak?n Emrah Bozbeyoglu Ertugrul Okuyan 《Medical principles and practice》2015,25(1):25-30