全文获取类型
收费全文 | 2569篇 |
免费 | 316篇 |
国内免费 | 61篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 132篇 |
妇产科学 | 47篇 |
基础医学 | 347篇 |
口腔科学 | 24篇 |
临床医学 | 267篇 |
内科学 | 593篇 |
皮肤病学 | 32篇 |
神经病学 | 189篇 |
特种医学 | 411篇 |
外科学 | 270篇 |
综合类 | 62篇 |
一般理论 | 1篇 |
预防医学 | 222篇 |
眼科学 | 24篇 |
药学 | 152篇 |
中国医学 | 6篇 |
肿瘤学 | 153篇 |
出版年
2022年 | 15篇 |
2021年 | 35篇 |
2020年 | 23篇 |
2019年 | 26篇 |
2018年 | 38篇 |
2017年 | 36篇 |
2016年 | 19篇 |
2015年 | 41篇 |
2014年 | 46篇 |
2013年 | 72篇 |
2012年 | 73篇 |
2011年 | 98篇 |
2010年 | 66篇 |
2009年 | 64篇 |
2008年 | 83篇 |
2007年 | 127篇 |
2006年 | 76篇 |
2005年 | 93篇 |
2004年 | 74篇 |
2003年 | 88篇 |
2002年 | 72篇 |
2001年 | 78篇 |
2000年 | 80篇 |
1999年 | 78篇 |
1998年 | 98篇 |
1997年 | 57篇 |
1996年 | 87篇 |
1995年 | 63篇 |
1994年 | 57篇 |
1993年 | 72篇 |
1992年 | 61篇 |
1991年 | 65篇 |
1990年 | 76篇 |
1989年 | 86篇 |
1988年 | 83篇 |
1987年 | 87篇 |
1986年 | 64篇 |
1985年 | 59篇 |
1984年 | 52篇 |
1983年 | 26篇 |
1982年 | 21篇 |
1981年 | 36篇 |
1980年 | 37篇 |
1979年 | 32篇 |
1978年 | 23篇 |
1977年 | 29篇 |
1976年 | 19篇 |
1975年 | 22篇 |
1974年 | 17篇 |
1973年 | 19篇 |
排序方式: 共有2946条查询结果,搜索用时 15 毫秒
1.
Uptake of iodine-123 MIBG by pheochromocytomas, paragangliomas, and neuroblastomas: a histopathological comparison 总被引:2,自引:0,他引:2
J Bomanji D A Levison W D Flatman T Horne P M Bouloux G Ross K E Britton G M Besser 《Journal of nuclear medicine》1987,28(6):973-978
The percentage uptake of [123I]metaiodobenzylguanidine (MIBG) by tumors of the paraganglion system is compared with the number of neurosecretory granules (assessed by both light and electron microscopy) in the subsequently resected tumors in six patients. Iodine-123 MIBG was injected intravenously; the tumor uptake of [123I]MIBG varied between 0.001% and 0.14% of the injected dose per gram of tumor tissue at 22 hr. The number of neurosecretory granules in tissue sections was scored on a scale of I-III. A direct proportional correlation was found between the percentage uptake of [123I]MIBG by the tumor and the number of neurosecretory granules in the tissue sections but not with plasma or urinary catecholamines. This technique for imaging reflects the storage status of the tumor better than plasma and urinary catecholamine measurements. 相似文献
2.
The requirements, problems and progress of radioimmunotherapy in the management of certain malignancies are described. The future prospects using a two- or three-stage approach are promising. 相似文献
3.
4.
Israel Liberzon Stephan F Taylor K Luan Phan Jennifer C Britton Lorraine M Fig Joshua A Bueller Robert A Koeppe Jon-Kar Zubieta 《Neuropsychopharmacology》2007,61(9):1030-1038
BACKGROUND: Functional neuroimaging studies have detected abnormal limbic and paralimbic activation to emotional probes in posttraumatic stress disorder (PTSD), but few studies have examined neurochemical mechanisms that underlie functional alterations in regional cerebral blood flow. The mu-opioid neurotransmitter system, implicated in responses to stress and suppression of pain, is distributed in and is thought to regulate the function of brain regions that are implicated in affective processing. METHODS: Here we examined the micro-opioid system with positron emission tomography and the micro-opioid receptor-selective radiotracer [11C] carfentanil in 16 male patients with PTSD and two non-PTSD male control groups, with (n = 14) and without combat exposure (n = 15). Differences in micro-opioid receptor binding potential (BP2) were detected within discrete limbic and paralimbic regions. RESULTS: Relative to healthy controls, both trauma-exposed groups had lower micro-opioid receptor BP2 in extended amygdala, nucleus accumbens, and dorsal frontal and insular cortex but had higher BP2 in the orbitofrontal cortex. PTSD patients exhibited reduced BP2 in anterior cingulate cortex compared with both control groups. Micro-opioid receptor BP2 in combat-exposed subjects without PTSD was lower in the amygdala but higher in the orbitofrontal cortex compared with both PTSD patients and healthy controls. CONCLUSIONS: These findings differentiate the general response of the micro-opioid system to trauma from more specific changes associated with PTSD. 相似文献
5.
6.
7.
8.
Sylvia Mitchell Veronica A. Bradley John L. Welch Peter G. Britton 《Brain injury : [BI]》1990,4(3):273-279
This study reports on the efficacy of a 'coma arousal procedure'. This procedure involved a programme of vigorous sensory stimulation administered to comatose patients by relatives using Comakits. An experimental group of 12 severely head-injured patients received the coma arousal procedure while a matched control group did not. Total duration of coma and weekly Glasgow Coma Scale Scores were recorded for the two groups. Results indicate that the total duration of coma was significantly shorter and that coma lightened more rapidly for the experimental group. 相似文献
9.
10.
Clinical evaluation of technetium-99m infecton for the localisation of bacterial infection 总被引:4,自引:3,他引:1
K. E. Britton S. Vinjamuri A. V. Hall K. Solanki Q. H. Siraj J. Bomanji S. Das 《European journal of nuclear medicine and molecular imaging》1997,24(5):553-556
The aim of the study was to distinguish infection from inflammation in patients with suspected infection using technetium-99m Infecton. Ninety-nine patients (102 studies) referred for infection evaluation underwent imaging with 400 MBq99mTc-Infecton at 1 and 4 h. Most patients had appropriate microbiological tests and about half (56) had radiolabelled white cell scans as well. No adverse effects were noted in any patient. The clinical efficacy of99mTc-Infecton depended in part on whether imaging was undertaken during intibiotic therapy for infection or not. In consultation with the microbiologist, 5–14 days of appropriate and successful antibiotic therapy was considered adequate to classify some results as true-negatives. The figures for sensitivity and specificity of99mTc-Infecton for active or unsuccessfully treated infection were 83% and 91% respectively. It is concluded that99mTc-Infecton imaging contributed to the differential diagnosis of inflammation. It is being used as the first imaging modality when bacterial infection is suspected. 相似文献