全文获取类型
收费全文 | 638篇 |
免费 | 40篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 15篇 |
妇产科学 | 13篇 |
基础医学 | 48篇 |
口腔科学 | 21篇 |
临床医学 | 106篇 |
内科学 | 145篇 |
皮肤病学 | 37篇 |
神经病学 | 28篇 |
特种医学 | 82篇 |
外国民族医学 | 1篇 |
外科学 | 55篇 |
综合类 | 37篇 |
预防医学 | 20篇 |
眼科学 | 2篇 |
药学 | 42篇 |
中国医学 | 1篇 |
肿瘤学 | 24篇 |
出版年
2022年 | 6篇 |
2021年 | 11篇 |
2020年 | 10篇 |
2019年 | 14篇 |
2018年 | 16篇 |
2017年 | 15篇 |
2016年 | 12篇 |
2015年 | 17篇 |
2014年 | 20篇 |
2013年 | 21篇 |
2012年 | 11篇 |
2011年 | 18篇 |
2010年 | 32篇 |
2009年 | 29篇 |
2008年 | 12篇 |
2007年 | 14篇 |
2006年 | 13篇 |
2005年 | 8篇 |
2004年 | 7篇 |
2003年 | 12篇 |
2002年 | 8篇 |
1999年 | 7篇 |
1998年 | 21篇 |
1997年 | 13篇 |
1996年 | 22篇 |
1995年 | 18篇 |
1994年 | 25篇 |
1993年 | 28篇 |
1992年 | 13篇 |
1991年 | 6篇 |
1989年 | 17篇 |
1988年 | 14篇 |
1987年 | 8篇 |
1986年 | 8篇 |
1985年 | 14篇 |
1983年 | 9篇 |
1982年 | 10篇 |
1981年 | 9篇 |
1980年 | 11篇 |
1979年 | 11篇 |
1978年 | 7篇 |
1977年 | 8篇 |
1976年 | 6篇 |
1975年 | 6篇 |
1957年 | 9篇 |
1956年 | 5篇 |
1955年 | 6篇 |
1954年 | 6篇 |
1949年 | 8篇 |
1948年 | 8篇 |
排序方式: 共有679条查询结果,搜索用时 15 毫秒
1.
2.
Doaa A. E. Abou‐Taleb Heba A. Abou‐Taleb Omnia El‐Badawy Asmaa O. Ahmed Alaa EL‐din Thabiet Hassan Sara M. Awad 《Dermatologic therapy》2019,32(5)
Intralesional (IL) vitamin D3 is an emerging treatment for cutaneous warts. However, its effectiveness and exact mechanism is not fully evaluated. We aimed to compare the efficacy and safety of IL purified protein derivative (PPD) and IL vitamin D3 in multiple warts and to investigate their systemic effect clinically and immunologically. Forty‐five patients with multiple extragenital warts were treated with IL‐PPD (22 patients) or IL vitamin D3 injection (23 patients) for a maximum of three sessions at 3 week intervals. Decrease in size and number of warts and adverse effects were evaluated. Serum interleukin‐12 (IL‐12) and interferon‐gamma (IFN‐γ) levels were measured before and 3 weeks after the last session. Higher clearance rates for all warts were observed with IL‐PPD compared to IL vitamin D (59.1% vs. 21.7% complete clearance, p < .001). Significant increase was found in both serum IL‐12 and IFN‐γ after PPD treatment (p = .034 and p = .04, respectively), but only IFN‐γ after vitamin D3 treatment (p = 0.02). Both IL vitamin D3 and PPD showed positive results in treatment of multiple warts. However, PPD showed higher clinical efficacy and more increase in both IL‐12 and IFN‐γ levels. 相似文献
3.
4.
5.
6.
Eman Hamid MD PhD Biniyam A. Ayele MD Daniel Gams Massi MD Samia Ben Sassi MD Houyam Tibar MD Emmanuel Epenge Djonga MD Sarah Misbah El-Sadig MD Wahiba AMER EL KHEDOUD MD Julien Razafimahefa MSc Ange Eric Kouame-Assouan MD Djibrilla Ben-Adji MD Yilédoma Thierry Modeste Lengané MD Abdu Kisekka Musubire MD Muhyadin Hassan Mohamed MSc Tiwonge Elisa Phiri MBBS FCN Nsengiyumva Nestor MD Wael Abdulgader Alwahchi MSc Saara Ndinelago Neshuku MBChB FCN MMed Cassandra Ocampo MD Foksouna Sakadi MD Moulid Ali Maidal MBBS Gift Wilson Ngwende MBChB MMed FCP Juzor Hooker MB ChB MMed DCN FCP Kigocha Okeng'o MD Med MSc Augustina Charway-Felli MD PhD FGCPS Masharip Atadzhanov PhD FRCP Jonathan Carr MBChB PhD Njideka U. Okubadejo MBChB FMCP FAAN Ali Shalash MD PhD 《Movement disorders》2021,36(10):2393-2407
7.
8.
9.
M Sun ; KH Chao ; LE Modahl ; G Leoung ; H Khayam-Bashi ; VL Ng ; EL Murphy 《Transfusion》1994,34(4):344-348
BACKGROUND: Asian Americans are generally underrepresented both as volunteer blood and bone marrow donors. STUDY DESIGN AND METHODS: To investigate the risk of transfusion transmission of viruses that is associated with increasing participation by Asian American donors, antibodies to human T-lymphotropic virus (HTLV), hepatitis C, and human immunodeficiency virus in Asian American volunteers recruited as potential bone marrow donors were measured. A total of 1354 Asian Americans were enrolled in the study, of whom 54 percent were Chinese, 26 percent Japanese, 9 percent Filipino, 4 percent Korean, 3 percent Indian, and 5 percent of other Asian or mixed Asian and other ethnicity. The majority of the study population was aged 20 through 49 and of high socioeconomic status, as indicated by education and income. Viral antibodies were measured with both screening enzyme-linked immunosorbent assays and supplemental testing, and polymerase chain reaction was used to resolve discrepant HTLV results. RESULTS: Confirmed seroprevalence rates for HTLV were 0.15 percent with one manufacturer's Western blot and 0.3 percent with the other; however, no sample was positive for HTLV types I or II in polymerase chain reaction. Confirmed seroprevalence to hepatitis C virus was 0.5 percent. No subject was seropositive for human immunodeficiency virus. CONCLUSION: On the basis of the moderate size and high education level of this study population, it is concluded that Asian American volunteer bone marrow donors do not pose a greater risk for transmission of HTLV type I or II, human immunodeficiency virus, or hepatitis C virus than does the average American blood donor. 相似文献
10.
Ultraviolet-B (UV-B) irradiation of platelet concentrates (PCs) may prevent the development of posttransfusion HLA alloimmunization. This study evaluated the effect of increasing doses of UV-B radiation on stored PCs. Pooled PCs were irradiated at UV-B doses of 600, 2400 or 10,000 mJ per cm2 and stored up to 96 hours under standard blood bank conditions. Compared to nonirradiated room-temperature and 37 degrees C controls, the irradiated units showed no significant changes in platelet count, white cell count, discharge of lactate dehydrogenase, release of beta-thromboglobulin, metabolism of ATP, ADP, ammonia, glutamine, glutamate, hypoxanthine, pCO2, or pO2 at any time of storage following any of the three UV-B doses. However, after a dose of 10,000 mJ per cm2, there were significant decreases in in vitro assays of platelet function-specifically, osmotic recovery and morphology score. Some metabolic systems were also affected by the 10,000 mJ per cm2 radiation dose, as shown by a decline in pH and bicarbonate and an increase in glucose consumption and lactate production (p < 0.05). The changes in these latter assays appeared only after 96 hours of postirradiation storage. Such changes were not seen in either the room- temperature or 37 degrees C control groups. Thus, heat generated during irradiation, per se, did not appear responsible for the observed in vitro changes in platelet function and metabolism. On the basis of the assays analyzed, it is concluded that UV-B irradiation of PCs at doses up to 10,000 mJ per cm2 does not induce significant metabolic or functional derangements following short-term storage (24-48 hours).(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献