全文获取类型
收费全文 | 809篇 |
免费 | 41篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 36篇 |
妇产科学 | 15篇 |
基础医学 | 48篇 |
口腔科学 | 28篇 |
临床医学 | 54篇 |
内科学 | 190篇 |
皮肤病学 | 23篇 |
神经病学 | 35篇 |
特种医学 | 16篇 |
外科学 | 191篇 |
综合类 | 27篇 |
预防医学 | 102篇 |
眼科学 | 14篇 |
药学 | 35篇 |
肿瘤学 | 31篇 |
出版年
2023年 | 10篇 |
2022年 | 11篇 |
2021年 | 26篇 |
2020年 | 17篇 |
2019年 | 17篇 |
2018年 | 27篇 |
2017年 | 18篇 |
2016年 | 29篇 |
2015年 | 43篇 |
2014年 | 28篇 |
2013年 | 50篇 |
2012年 | 57篇 |
2011年 | 75篇 |
2010年 | 39篇 |
2009年 | 39篇 |
2008年 | 31篇 |
2007年 | 46篇 |
2006年 | 46篇 |
2005年 | 35篇 |
2004年 | 32篇 |
2003年 | 27篇 |
2002年 | 34篇 |
2001年 | 15篇 |
2000年 | 6篇 |
1999年 | 6篇 |
1997年 | 4篇 |
1996年 | 7篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1993年 | 5篇 |
1992年 | 14篇 |
1991年 | 8篇 |
1990年 | 7篇 |
1989年 | 7篇 |
1988年 | 4篇 |
1987年 | 3篇 |
1986年 | 3篇 |
1985年 | 3篇 |
1984年 | 4篇 |
1983年 | 2篇 |
1982年 | 6篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 1篇 |
1972年 | 1篇 |
1970年 | 1篇 |
排序方式: 共有853条查询结果,搜索用时 171 毫秒
1.
Bahattin Kerem Aydin Hakan Sofu Hakan Senaran Omer Faruk Erkocak Mehmet Ali Acar Yunus Kirac 《Medicine》2015,94(47)
Randomized controlled clinical trial.The main purpose of the present study was to comparatively analyze the effectiveness, advantages, and the complications of using semirigid synthetic softcast with respect to plaster of Paris (POP) during the treatment of clubfoot deformity.The study group consisted of 196 babies (249 feet). A total of 133 feet treated by an orthopedic referral center using semirigid synthetic softcast were included in group A whereas the other 116 feet treated by another orthopedic clinic using POP cast were included in group B. The Pirani scores, number of cast applications, time period until Achilles tenotomy, any skin problems due to the cast itself, and/or cast removal were recorded. A final parent satisfaction score was also obtained.The mean Pirani sores were significantly improved from the first administration to the time before Achilles tenotomy in both groups. There was no significant difference according to the number of casts applied until tenotomy. The slippage of the cast and skin lesions was significantly more common in group B. Higher parent satisfaction levels were detected in group A.Semirigid softcast has been found as superior to POP in the aspects of parent satisfaction and cast-related complication rates. 相似文献
2.
3.
4.
Ahmet Salvarci Yunus Agrali 《International braz j urol : official journal of the Brazilian Society of Urology》2015,41(2):382-387
Laparoscopy began to be used widely since the second half of 1990s as an alternative to laparotomy or vaginal approaches in incontinence and pelvic diseases in women, based on its claimed better success rates. Injuries were reported in the bladder, gastrointestinal system and the entry of the Verress cannula in early and late laparoscopic applications. De-novo urging, voiding dysfunctions, marked recurrences and surgical inefficiencies were observed in 5-year follow-ups after laparoscopic incontinence surgery. Although tension-free midurethral sling operations replaced open laparoscopic colposuspensions nowadays, laparoscopic colposuspension is still preferred in cases where simultaneous laparoscopic paravaginal repair or sacrocolpopexy is considered or where synthetic graft implantation is contraindicated. Moreover, meshes and endotackers are still frequently used in many laparoscopic applications in various clinics. The migration of the tacker used in mesh fixation in a patient where retroperitoneal laparoscopic Burch was performed 7 years ago due to stress urinary incontinence and the extraction of the ossified tacker from the bladder will be presented. 相似文献
5.
6.
Egehan Yetişkin Özlem Gündoğdu Derya Mete Neslihan Çelebioğlu Yunus Kara Gülşah Şanlı-Mohamed 《Chemical biology & drug design》2023,102(6):1448-1457
In this study, synthesis of novel isoindole-1,3-dione analogues bearig halo, hydroxy, and acetoxy groups at the position 4,5,6 of the bicyclic imide ring was performed to examine their potential anticancer effects against some cell lines. A multistep chemical pathway was used to synthesize the derivatives. The cytotoxic effect of trisubstituted isoindole derivatives were evaluated by determining cellular viability using the MTT assay against A549, PC-3, HeLa, Caco-2, and MCF-7 cell lines. The C-2 selective ring-opening products were obtained from the ring-opening reaction of 5-alkyl/aryl-2-hydroxyhexahydro-4H-oxireno[2,3-e]isoindole-4,6(5H)-diones with nucleophiles such as chloride (Cl−) and bromide (Br−) ions. In addition, the ring-opening products halodiols were converted to their related acetates. The anticancer activity of synthesized isoindole-1,3-dione derivatives was investigated against HeLa, A549, MCF-7, PC3, and Caco-2 cells in vitro and resulted in varies cytotoxic effect depend on the group attached to the isoindole molecule. Furthermore, the evaluation of the antimicrobial action of trisubstituted isoindole derivatives against Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria was assessed and found out selective inhibition of the both bacterial growth via different trisubstituted isoindole derivatives. The results of this work encourage further research on the potential utilization of trisubstituted isoindole derivatives as cytotoxic and antimicrobial agents. 相似文献
7.
8.
MM Muquith MN Islam SA Haq PM Ten Klooster JJ Rasker MB Yunus 《BMC musculoskeletal disorders》2012,13(1):157
ABSTRACT: BACKGROUND: Currently, no validated instruments are available to measure the health status of Bangladeshi patients with fibromyalgia (FM). The aims of this study were to cross-culturally adapt the modified Fibromyalgia Impact Questionnaire (FIQ) into Bengali (B-FIQ) and to test its validity and reliability in Bangladeshi patients with FM. METHODS: The FIQ was translated following cross-cultural adaptation guidelines and pretested in 30 female patients with FM. Next, the adapted B-FIQ was physician-administered to 102 consecutive female FM patients together with the Health Assessment Questionnaire (HAQ), selected subscales of the SF-36, and visual analog scales for current clinical symptoms. A tender point count (TPC) was performed by an experienced rheumatologist. Forty randomly selected patients completed the B-FIQ again after 7 days. Two control groups of 50 healthy people and 50 rheumatoid arthritis (RA) patients also completed the B-FIQ. RESULTS: For the final B-FIQ, five physical function sub-items were replaced with culturally appropriate equivalents. Internal consistency was adequate for both the 11-item physical function subscale (alpha = 0.73) and the total scale (alpha = 0.83). With exception of the physical function subscale, expected correlations were generally observed between the B-FIQ items and selected subscales of the SF-36, HAQ, clinical symptoms, and TPC. The B-FIQ was able to discriminate between FM patients and healthy controls and between FM patients and RA patients. Test-retest reliability was adequate for the physical function subscale (r = 0.86) and individual items (r = 0.73-0.86), except anxiety (r = 0.27) and morning tiredness (r = 0.64). CONCLUSION: This study supports the reliability and validity of the B-FIQ as a measure of functional disability and health status in Bangladeshi women with FM. 相似文献
9.
Demet Tekdos Demircioglu Nurdan Paker Elif Erbil Derya Bugdayci Tuluhan Yunus Emre 《Journal of Physical Therapy Science》2015,27(8):2501-2506
[Purpose] The aim of this study was to investigate the effect of the addition of NMES to
the post-TKA rehabilitation protocol on the functional status and quality of life of the
patients. [Subjects and Methods] Patients were randomized into an exercise (control) and
electrical stimulation (NMES) group. A home exercise program was prescribed for the
control group. For the neuromuscular stimulation group 30 minute electrical stimulation
applied to the vastus medialis muscle 5 days a week for 4 to 6 weeks. VAS, the timed up
and go test, WOMAC and SF-36 scores were evaluated preoperatively and postoperatively at
the first month and the third month of the follow-up period. [Results] Both the NMES group
had 30 patients each, with 2 and 1 male patients respectively. The comparisons of WOMAC
results at month 1 revealed that pain, stiffness, and total scores of the NMES group was
significantly better than those of control group at the first and third months.
Significantly better physical function and SF-36 subscales, except mental health, were
found for the NMES group at the first month of follow-up. [Conclusion] The inclusion of
the neuromuscular electrical stimulation program after knee arthroplasty was more
effective at providing rapid improvements in knee pain, walking distance and quality of
life.Key words: Quadriceps muscle, Knee joint, Arthroplasty 相似文献
10.
Max Wagener Gino Lee Fabio Stallone Tanja Marxer Christian Puelacher Carmela Schumacher Seoung Mann Sou Raphael Twerenbold Tobias Reichlin Thomas Hochgruber Yunus Tanglay Michael Freese Damian Wild Katharina Rentsch Stefan Osswald Michael Zellweger Christian Mueller 《European journal of clinical investigation》2015,45(11):1175-1183