全文获取类型
收费全文 | 2388篇 |
免费 | 140篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 9篇 |
儿科学 | 65篇 |
妇产科学 | 65篇 |
基础医学 | 271篇 |
口腔科学 | 42篇 |
临床医学 | 163篇 |
内科学 | 553篇 |
皮肤病学 | 31篇 |
神经病学 | 122篇 |
特种医学 | 66篇 |
外科学 | 395篇 |
综合类 | 45篇 |
一般理论 | 1篇 |
预防医学 | 140篇 |
眼科学 | 71篇 |
药学 | 170篇 |
中国医学 | 9篇 |
肿瘤学 | 322篇 |
出版年
2023年 | 17篇 |
2022年 | 15篇 |
2021年 | 97篇 |
2020年 | 42篇 |
2019年 | 83篇 |
2018年 | 124篇 |
2017年 | 101篇 |
2016年 | 77篇 |
2015年 | 48篇 |
2014年 | 121篇 |
2013年 | 132篇 |
2012年 | 180篇 |
2011年 | 175篇 |
2010年 | 139篇 |
2009年 | 130篇 |
2008年 | 113篇 |
2007年 | 109篇 |
2006年 | 93篇 |
2005年 | 89篇 |
2004年 | 86篇 |
2003年 | 72篇 |
2002年 | 67篇 |
2001年 | 26篇 |
2000年 | 19篇 |
1999年 | 11篇 |
1998年 | 14篇 |
1997年 | 9篇 |
1996年 | 13篇 |
1995年 | 15篇 |
1994年 | 11篇 |
1993年 | 15篇 |
1992年 | 11篇 |
1991年 | 17篇 |
1990年 | 20篇 |
1989年 | 24篇 |
1988年 | 17篇 |
1987年 | 15篇 |
1986年 | 14篇 |
1985年 | 15篇 |
1983年 | 16篇 |
1981年 | 9篇 |
1980年 | 13篇 |
1979年 | 15篇 |
1978年 | 13篇 |
1974年 | 11篇 |
1973年 | 12篇 |
1972年 | 10篇 |
1971年 | 7篇 |
1970年 | 9篇 |
1966年 | 7篇 |
排序方式: 共有2540条查询结果,搜索用时 125 毫秒
1.
2.
3.
4.
Jerry R. Paugh Alba Alfonso-Garcia Andrew Loc Nguyen Jeffrey L. Suhalim Marjan Farid Sumit Garg Jeremiah Tao Donald J. Brown Eric O. Potma James V. Jester 《The ocular surface》2019,17(1):151-159
Purpose
This study examined whether hyperspectral stimulated Raman scattering (hsSRS) microscopy can detect differences in meibum lipid to protein composition of normal and evaporative dry eye subjects with meibomian gland dysfunction.Methods
Subjects were evaluated for tear breakup time (TBUT), staining, meibum expression and gland dropout. Expressed meibum was analyzed using SRS vibrational signatures in the CH stretching region (2800–3050?cm?1). Vertex component analysis and K-means clustering were used to group the spectral signatures into four fractions containing high lipid (G1) to high protein (G4).Results
Thirty-three subjects could be statistically analyzed using pooled meibum (13 with stable tear films (TBUTs?>?10?s) and 20 with unstable tear films (TBUTs?≤?10?s). Significant differences in meibum from subjects with unstable vs. stable TBUTs were found for the G1 fraction (medians 0.164 and 0.020, respectively; p?=?0.012) and the G2 fraction (medians 0.244 and 0.272, respectively; p?=?0.045). No differences were observed for the G3 and G4 fractions. Single orifice samples were not significantly different vs. pooled samples from the fellow eye, and eyelid sector samples (nasal, central and temporal) G2:G3 fractional components were not significantly different (p?=?0.449). Spearman analysis suggested a significant inverse correlation between G1 fraction and TBUT (R?=??0.351; p?=?0.045).Conclusions
hsSRS microscopy allows compositional analysis of expressed meibum from humans which correlated to changes in TBUT. These findings support the hypothesis that hsSRS may be useful in classifying meibum quality and evaluating the effects of therapy. 相似文献5.
6.
7.
8.
Farid Saad 《Asian journal of andrology》2015,17(1):58-60
It is no exaggeration to say that our conceptualization of the (patho-) physiological functions of testosterone has undergone a revolutionary development over the last three decades. The traditional thinking was that the biological functions of testosterone were restricted mainly to the area of reproduction and male sexuality. However, scientific research has clearly demonstrated that testosterone is a multi-system hormone serving a wide range of hitherto unsuspected biological functions.In line with this, it will be argued in this contribution that the physiological role of testosterone has been underestimated, while the risks of testosterone administration have been overstated. Space does not permit to elaborate extensively on all new insights of the role of testosterone in the biology of the male. Three areas will be addressed: (1) the role that testosterone can play in body weight management of hypogonadal men; (2) the role of testosterone in inflammatory processes; (3) the strategy required to let patients benefit from the recent insights that testosterone is a multi-system hormone whose use should not be limited to reproductive/sexual medicine. 相似文献
9.
10.