全文获取类型
收费全文 | 1151篇 |
免费 | 83篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 10篇 |
儿科学 | 21篇 |
妇产科学 | 22篇 |
基础医学 | 142篇 |
口腔科学 | 106篇 |
临床医学 | 91篇 |
内科学 | 253篇 |
皮肤病学 | 11篇 |
神经病学 | 151篇 |
特种医学 | 24篇 |
外科学 | 161篇 |
综合类 | 10篇 |
一般理论 | 1篇 |
预防医学 | 76篇 |
眼科学 | 26篇 |
药学 | 86篇 |
中国医学 | 1篇 |
肿瘤学 | 45篇 |
出版年
2023年 | 11篇 |
2022年 | 13篇 |
2021年 | 38篇 |
2020年 | 37篇 |
2019年 | 42篇 |
2018年 | 48篇 |
2017年 | 23篇 |
2016年 | 44篇 |
2015年 | 34篇 |
2014年 | 57篇 |
2013年 | 48篇 |
2012年 | 93篇 |
2011年 | 81篇 |
2010年 | 44篇 |
2009年 | 45篇 |
2008年 | 81篇 |
2007年 | 69篇 |
2006年 | 63篇 |
2005年 | 49篇 |
2004年 | 49篇 |
2003年 | 55篇 |
2002年 | 37篇 |
2001年 | 11篇 |
2000年 | 14篇 |
1999年 | 9篇 |
1998年 | 9篇 |
1997年 | 3篇 |
1995年 | 3篇 |
1994年 | 2篇 |
1992年 | 5篇 |
1990年 | 14篇 |
1989年 | 6篇 |
1988年 | 15篇 |
1987年 | 6篇 |
1986年 | 4篇 |
1985年 | 8篇 |
1984年 | 5篇 |
1983年 | 4篇 |
1982年 | 5篇 |
1981年 | 4篇 |
1977年 | 2篇 |
1976年 | 2篇 |
1975年 | 5篇 |
1974年 | 11篇 |
1973年 | 4篇 |
1972年 | 7篇 |
1971年 | 3篇 |
1970年 | 4篇 |
1969年 | 2篇 |
1965年 | 1篇 |
排序方式: 共有1237条查询结果,搜索用时 171 毫秒
1.
2.
Jara Ampuero Mencía Almudena Vega Soraya Abad Caridad Ruiz Caro Úrsula Verdalles Juan Manuel López Gómez 《Nefrología : publicación oficial de la Sociedad Espa?ola Nefrologia》2019,39(1):44-49
Background
Hypertension is a highly prevalent disorder among patients undergoing haemodialysis. It contributes to greater cardiovascular risk and must be controlled. However, despite dietary measures, haemodialysis regimen optimisation and pharmacological treatment, some patients in our units continue to maintain high blood pressure levels. The objective of the study is to demonstrate that reducing calcium in dialysis fluid can help treat hypertension patients undergoing haemodialysis.Material and methods
We selected all of the hypertensive patients from our haemodialysis unit. We checked their normovolemic status by means of bioimpedance spectroscopy, decreasing the haemodialysis fluid's calcium concentration to 2.5 mEq/l, with a follow-up period of 12 months.Results
A total of 24 patients met the non-volume dependent hypertension criteria (age 61 ± 15 years, males 48%, diabetes 43%). A significant systolic and diastolic blood pressure decrease was observed at 6 and 12 months as a result of reducing the dialysis calcium concentration; this was not accompanied by greater haemodynamic instability (baseline systolic blood pressure: 162 ± 14 mmHg; at 6 months: 146 ± 18 mmHg; at 12 months: 141 ± 21 mmHg; P = .001) (baseline diastolic blood pressure: 76 ± 14 mmHg; at 6 months: 70 ± 12 mmHg; at 12 months: 65 ± 11 mmHg; P = .005). A non-significant increase in plasma parathyroid hormone levels was also found. No side effects were observed.Conclusions
Adding 2.5 mEq/l of calcium to dialysis fluid is a safe and effective therapeutic alternative to control hard-to-manage hypertension among haemodialysis patients. 相似文献3.
4.
5.
6.
7.
Drug use,health and social outcomes of hard‐to‐treat heroin addicts receiving supervised injectable opiate treatment: secondary outcomes from the Randomized Injectable Opioid Treatment Trial (RIOTT) 下载免费PDF全文
8.
9.
Three different methods of instruction and motivation were used to assess the learning process and ability of preschool children in performing toothbrushing. Forty children from a private nursery of Brasília, DF, Brazil, were divided into 2 groups according to age (3-4 years old and 5-6 years old). The following methods of instruction and reinforcement were applied: I--audiovisual; II--child as a model; III--individual instruction. Professional prophylaxis was then performed and the children remained 48 hours without any kind of oral hygiene. Plaque disclosing and plaque index were carried out and recorded. The children subsequently brushed their teeth according to each method of instruction and a new plaque index was recorded. The data were analyzed statistically using the Student t-test and the comparison of two proportions. The results showed that the children of both groups reduced plaque index and that the individual instruction method was superior (p<0.05) to the others at all ages. Children older than 5 years of age were able to learn and accomplish toothbrushing better than younger children. 相似文献
10.
Serious difficulties in reporting results were encountered when using ICDAS II and PUFA separately in an epidemiological survey in a child population in Brazil. That necessitated the development of a comprehensive but pragmatic caries assessment index. This publication describes the rationale, development and content of a novel caries assessment index. Strengths and weaknesses of ICDAS II, PUFA and other indices were analysed. The novel caries index developed for use in epidemiological surveys is termed 'Caries Assessment Spectrum and Treatment' (CAST). 'Spectrum' indicates what is considered the main strength of the new index - its usefulness in describing the complete range of stages of carious lesion progression: from no carious lesion, through caries protection (sealant) and caries cure (restoration) to lesions in enamel and dentine, and the advanced stages of carious lesion progression in pulpal and tooth-surrounding tissue. CAST combines elements of the ICDAS II and PUFA indices, and the M- and F-components of the DMF index. A DMF score can easily be calculated from the CAST score, thereby enabling retention of the use of existing DMF scores. The CAST index for use in epidemiological surveys is very promising. It should be validated and its reliability and usefulness be tested in different age groups in different countries and cultures. 相似文献