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Nicosia Antonino Iacopino Saverio Nigro Gerardo Zucchelli Giulio Tomasi Luca D’Agostino Carlo Ziacchi Matteo Piacenti Marcello De Filippo Paolo Sgarito Giuseppe Campisi Giuseppe Nicolis Daniele Foti Rosario Palmisano Pietro 《Journal of interventional cardiac electrophysiology》2022,63(1):103-108
Journal of Interventional Cardiac Electrophysiology - Advanced non-fluoroscopic mapping systems for radiofrequency ablation (RFA) have shown to be an effective treatment of atrial fibrillation.... 相似文献
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Giuseppe Stabile Antoine Lepillier Ermenegildo De Ruvo Marco Scaglione Matteo Anselmino Frederic Sebag Domenico Pecora Mark Gallagher Mariano Rillo Graziana Viola Luca Rossi Valerio De Santis Maurizio Landolina Antonello Castro Massimo Grimaldi Nicolas Badenco Maurizio Del Greco Antonio De Simone Ennio Pisan Salim Abbey Filippo Lamberti Antonio Pani Giulio Zucchelli Giuseppe Sgarito Daniela Dugo Emanuele Bertaglia Teresa Strisciuglio Francesco Solimene 《Journal of cardiovascular electrophysiology》2020,31(7):1694-1701
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Sergio Conti MD PhD Francesco Sabatino MD Carlo Caserta MD Giuseppe Sgarito MD PhD 《Echocardiography (Mount Kisco, N.Y.)》2023,40(3):271-275
Patients with mitral valve prolapse (MVP) have a heterogeneous clinical spectrum, ranging from benign to severe clinical presentations such as sudden cardiac death (SCD). Some of the markers of “arrhythmic MVP” include inverted/biphasic T-waves, QT prolongation, and polymorphic premature ventricular contractions (PVCs) originating from the left ventricular outflow tract and papillary muscles (PMs). The genesis of arrhythmias in MVP recognizes the combination of the substrate (fibrosis) and the trigger (mechanical stretch). Therefore, ablation of ventricular arrhythmias originating from PMs in a patient with MVP can be considered an adjunctive strategy to lower the arrhythmic burden and reduce the risk of ICD shocks. 相似文献
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Michela Casella MD PhD Sergio Conti MD PhD Paolo Compagnucci MD Valentina Ribatti MD PhD Maria Lucia Narducci MD PhD Lorenzo Marcon MD Francesca Massara MD Yari Valeri MD Luca De Francesco MD Anna Maria Martino MD PhD Chiara Ghiglieno MD Marco Schiavone MD Cristina Balla MD Gabriele Dell'Era MD Gemma Pelargonio MD PhD Giovanni Battista Forleo MD PhD Saverio Iacopino MD Giuseppe Sgarito MD PhD Leonardo Calò MD FESC Claudio Tondo MD PhD Antonio Dello Russo MD PhD Giuseppe Patti MD 《Journal of cardiovascular electrophysiology》2023,34(6):1386-1394
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Giuseppe Boriani Lorenzo Giovanni Mantovani Paolo Angelo Cortesi Roberto De Ponti Antonio D'Onofrio Giuseppe Arena Antonio Curnis Giovanni Forleo Federico Guerra Maurizio Porcu Giuseppe Sgarito Giovanni Luca Botto 《Clinical cardiology》2021,44(11):1497
AimsPatients with permanently increased risk of sudden cardiac death (SCD) can be protected by implantable cardioverter defibrillators (ICD). If an ICD must be removed due to infection, for example, immediate reimplantation might not be possible or indicated. The wearable cardioverter defibrillator (WCD) is an established, safe and effective solution to protect patients from SCD during this high‐risk bridging period. Very few economic evaluations on WCD use are currently available.MethodsWe conducted a systematic review to evaluate the available evidence of WCD in patients undergoing ICD explant/lead extraction. Additionally, a decision model was developed to compare use and costs of the WCD with standard therapy (in‐hospital stay). For this purpose, a cost‐minimization analysis was conducted, and complemented by a one‐way sensitivity analysis.ResultsIn the base case scenario, the WCD was less expensive compared to standard therapy. The cost‐minimization analysis showed a cost reduction of €1782 per patient using the WCD. If costs of standard care were changed, cost savings associated with the WCD varied from €3500 to €0, assuming costs for standard care of €6800 to €3600.ConclusionAfter ICD explantation, patients can be safely and effectively protected from SCD after hospital discharge through WCD utilization. Furthermore, the use of a WCD for this patient group is cost saving when compared to standard therapy. 相似文献
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Camilla Terziotti Chiara Ceolin Maria Devita Cecilia Raffaelli Sara Antenucci Salvatore Bazzano Andrea Capasso Manuela Castellino Stefania Del Signore Francesca Lubian Mariangela Maiotti Fiammetta Monacelli Maria Teresa Mormile Claudia Sgarito Filomena Vella Giuseppe Sergi Pietro Gareri Caterina Trevisan Andrea Bellio Filippo Fini Alba Malara Enrico Mossello Stefano Fumagalli Stefano Volpato Fabio Monzani Giuseppe Bellelli Gianluca Zia Raffaele Antonelli Incalzi Alessandra Coin 《Psychogeriatrics》2023,23(6):1007-1018
Background
The containment measures linked to the COVID-19 pandemic negatively affected the phyco-physical well-being of the population, especially older adults with neurocognitive disorders (NCDs). This study aims to evaluate whether the frailty of NCD patients was associated with different changes in multiple health domains, in particular in relation to loneliness and social isolation, pre- and post-lockdown.Materials and Methods
Patients were recruited from 10 Italian Centers for Cognitive Disorders and Dementia. Data were collected in the pre-pandemic period (T0), during the pandemic lockdown (T1), and 6–9 months post-lockdown (T2). The UCLA Loneliness Scale-3, Activities of Daily Living (ADL), Instrumental ADL (IADL), Mini-Mental State Examination, and Neuropsychiatric Inventory (NPI) were administered. Caregivers' burden was also tested. Patients were categorized as non-frail, pre-frail, and frail according to the Fatigue, Resistance, Ambulation, Illness, and Loss of Weight scale.Results
The sample included 165 subjects (61.9% women, mean age 79.5 ± 4.9 years). In the whole sample, the ADL, IADL, and NPI scores significantly declined between T0 and T2. There were no significative variations in functional and cognitive domains between the frail groups. During lockdown we recorded higher Depression Anxiety Stress Scales and Perceived Stress Scale scores in frail people. In multivariable logistic regression, frailty was associated with an increase in social isolation, and a loss of IADL.Conclusions
We observed a global deterioration in functional and neuro-psychiatric domains irrespective of the degree of frailty. Frailty was associated with the worsening of social isolation during lockdown. Frail patients and their caregivers seemed to experience more anxiety and stress disorders during SARS-CoV-2 pandemic. 相似文献8.
Gianfranco Ciaramitaro Giuseppe Sgarito Michele Farinella Pierpaolo Prestifilippo Pasquale Assennato Salvatore Novo 《Italian heart journal. Supplement》2005,6(10):627-634
Early after the beginning of the pacemaker era, endocardial right ventricular apex has been the most extensively used site for cardiac pacing because it was easily accessible and reliable in a long-term perspective. However many data have demonstrated that this kind of pacing is suboptimal from a physiologic point of view because it causes several adverse effects such as altered ventricular contraction geometry, mitral regurgitation, perfusion alterations and interference with myocardial ion channels which determine a worsening of left ventricular function. Several strategies have been proposed to solve these problems (alternative pacing sites, specific algorithms able to reduce the percentage of ventricular pacing) which are still under evaluation. In this review we analyzed the effects of right apical ventricular pacing and its possible alternatives. 相似文献
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Ciaramitaro G Sgarito G Solimene F Maglia G Vicentini A DI Donato G Raciti G Parrinello G Del Giudice GB 《Pacing and clinical electrophysiology : PACE》2006,29(8):866-874
Aim: High heart rates in chronic atrial fibrillation (CAF) is one of the factors responsible for hemodynamic alterations and may lead to tachycardiomyopathies. The ventricular rate regulation (VRR) study evaluates the effect of ventricular rate regularization in CAF patients with preserved ventricular function, marked ventricular rate variability, and indications for pacemaker (PM) implantation owing to symptomatic pauses. Rate regularization was achieved using VRR algorithm (INSIGNIA® pacemakers, Guidant Corp., St. Paul, MN, USA) .
Methods: One month after PM implantation, 58 patients followed two 3-month crossover periods (VRR-OFF; VRR-ON) in which the VRR algorithm was randomized and compared to fixed rate stimulation at 60 ppm. During follow-up visits a 6-minute walk test was performed under partially inhibited conditions (PM at 40 ppm) and ventricular response was recorded. The following parameters were measured: mean ventricular rate (MR), rate variability (RR30), rate recovery after exercise (SLOPE = (R-END – R-REC)/(R-END – 40)), R-END being the rate at end of walk and R-REC the rate 1 minute after exercise.
Results: The VRR algorithm decreased rate variability (RR30: −7.36 ± 8.8; P < 0.01) without increasing ventricular rate (MR: −1.11 ± 8.3 P = NS), while SLOPE improved significantly (SLOPE: +15.41 ± 16.8 P < 0.01).
Conclusions: VRR effectively stabilizes rate, without increasing pacing rate above spontaneous rhythm and helps achieve a more favorable autonomic balance, improving rate recovery after exercise. 相似文献
Methods: One month after PM implantation, 58 patients followed two 3-month crossover periods (VRR-OFF; VRR-ON) in which the VRR algorithm was randomized and compared to fixed rate stimulation at 60 ppm. During follow-up visits a 6-minute walk test was performed under partially inhibited conditions (PM at 40 ppm) and ventricular response was recorded. The following parameters were measured: mean ventricular rate (MR), rate variability (RR30), rate recovery after exercise (SLOPE = (R-END – R-REC)/(R-END – 40)), R-END being the rate at end of walk and R-REC the rate 1 minute after exercise.
Results: The VRR algorithm decreased rate variability (RR30: −7.36 ± 8.8; P < 0.01) without increasing ventricular rate (MR: −1.11 ± 8.3 P = NS), while SLOPE improved significantly (SLOPE: +15.41 ± 16.8 P < 0.01).
Conclusions: VRR effectively stabilizes rate, without increasing pacing rate above spontaneous rhythm and helps achieve a more favorable autonomic balance, improving rate recovery after exercise. 相似文献
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