首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   2354204篇
  免费   171666篇
  国内免费   3336篇
耳鼻咽喉   32097篇
儿科学   76026篇
妇产科学   62771篇
基础医学   348775篇
口腔科学   63700篇
临床医学   211923篇
内科学   458061篇
皮肤病学   51752篇
神经病学   185681篇
特种医学   88105篇
外国民族医学   489篇
外科学   354211篇
综合类   47571篇
现状与发展   12篇
一般理论   851篇
预防医学   183185篇
眼科学   54524篇
药学   175368篇
  11篇
中国医学   4577篇
肿瘤学   129516篇
  2021年   19030篇
  2019年   19591篇
  2018年   27124篇
  2017年   20395篇
  2016年   22812篇
  2015年   25716篇
  2014年   36200篇
  2013年   54083篇
  2012年   74835篇
  2011年   79609篇
  2010年   47167篇
  2009年   44659篇
  2008年   74769篇
  2007年   79668篇
  2006年   80501篇
  2005年   77955篇
  2004年   74536篇
  2003年   71817篇
  2002年   69540篇
  2001年   108857篇
  2000年   111582篇
  1999年   93585篇
  1998年   27033篇
  1997年   23699篇
  1996年   24087篇
  1995年   22754篇
  1994年   20929篇
  1993年   19750篇
  1992年   72077篇
  1991年   70173篇
  1990年   68476篇
  1989年   65771篇
  1988年   60385篇
  1987年   59211篇
  1986年   55321篇
  1985年   53077篇
  1984年   39384篇
  1983年   33451篇
  1982年   19887篇
  1979年   35930篇
  1978年   25692篇
  1977年   21276篇
  1976年   20358篇
  1975年   21853篇
  1974年   26187篇
  1973年   24842篇
  1972年   23238篇
  1971年   22074篇
  1970年   20271篇
  1969年   19343篇
排序方式: 共有10000条查询结果,搜索用时 21 毫秒
1.
2.
3.
We report two British cases of liver abscess, due to Klebsiella pneumoniae and associated with synchronous infection elsewhere, which required liver resection for definitive treatment. They illustrate the geographic spread of aggressive K pneumoniae liver infection and demonstrate the importance of early aggressive treatment.  相似文献   
4.
Dosage form is a mean used for the delivery of drug to a living body. In order to get the desired effect the drug should be delivered to its site of action at such rate and concentration to achieve the maximum therapeutic effect and minimum adverse effect. Since oral route is still widely accepted route but having a common drawback of difficulty in swallowing of tablets and capsules. Therefore a lot of research has been done on novel drug delivery systems. This review is about oral dispersible tablets a novel approach in drug delivery systems that are now a day''s more focused in formulation world, and laid a new path that, helped the patients to build their compliance level with the therapy, also reduced the cost and ease the administration especially in case of pediatrics and geriatrics. Quick absorption, rapid onset of action and reduction in drug loss properties are the basic advantages of this dosage form.  相似文献   
5.
6.
Hepatic NADPH-cytochrome P450 oxidoreductase null (HRN?) mice exhibit normal hepatic and extrahepatic biotransformation enzyme activities when compared to wild-type (WT) mice, but express no functional hepatic cytochrome P450 activities. When incubated in vitro with [14C]-diclofenac, liver microsomes from WT mice exhibited extensive biotransformation to oxidative and glucuronide metabolites and covalent binding to proteins was also observed. In contrast, whereas glucuronide conjugates and a quinone-imine metabolite were formed when [14C]-diclofenac was incubated with HRN? mouse liver, only small quantities of P450-derived oxidative metabolites were produced in these samples and covalent binding to proteins was not observed. Livers from vehicle-treated HRN? mice exhibited enhanced lipid accumulation, bile duct proliferation, hepatocellular degeneration and necrosis and inflammatory cell infiltration, which were not present in livers from WT mice. Elevated liver-derived alanine aminotransferase, glutamate dehydrogenase and alkaline phosphatase activities were also observed in plasma from HRN? mice. When treated orally with diclofenac for 7 days, at 30 mg/kg/day, the severities of the abnormal liver histopathology and plasma liver enzyme findings in HRN? mice were reduced markedly. Oral diclofenac administration did not alter the liver histopathology or elevate plasma enzyme activities of WT mice. These findings indicate that HRN? mice are valuable for exploration of the role played by hepatic P450s in drug biotransformation, but poorly suited to investigations of drug-induced liver toxicity. Nevertheless, studies in HRN? mice could provide novel insights into the role played by inflammation in liver injury and may aid the evaluation of new strategies for its treatment.  相似文献   
7.
8.
9.
10.
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号