全文获取类型
收费全文 | 1778篇 |
免费 | 89篇 |
国内免费 | 3篇 |
专业分类
耳鼻咽喉 | 11篇 |
儿科学 | 53篇 |
妇产科学 | 60篇 |
基础医学 | 209篇 |
口腔科学 | 22篇 |
临床医学 | 146篇 |
内科学 | 352篇 |
皮肤病学 | 37篇 |
神经病学 | 86篇 |
特种医学 | 117篇 |
外科学 | 364篇 |
综合类 | 41篇 |
一般理论 | 1篇 |
预防医学 | 121篇 |
眼科学 | 26篇 |
药学 | 101篇 |
中国医学 | 6篇 |
肿瘤学 | 117篇 |
出版年
2023年 | 23篇 |
2022年 | 13篇 |
2021年 | 46篇 |
2020年 | 42篇 |
2019年 | 62篇 |
2018年 | 58篇 |
2017年 | 37篇 |
2016年 | 36篇 |
2015年 | 42篇 |
2014年 | 85篇 |
2013年 | 86篇 |
2012年 | 123篇 |
2011年 | 132篇 |
2010年 | 54篇 |
2009年 | 55篇 |
2008年 | 97篇 |
2007年 | 107篇 |
2006年 | 106篇 |
2005年 | 81篇 |
2004年 | 75篇 |
2003年 | 61篇 |
2002年 | 44篇 |
2001年 | 25篇 |
2000年 | 37篇 |
1999年 | 21篇 |
1998年 | 18篇 |
1997年 | 9篇 |
1995年 | 8篇 |
1992年 | 25篇 |
1991年 | 13篇 |
1990年 | 17篇 |
1989年 | 15篇 |
1988年 | 9篇 |
1987年 | 15篇 |
1986年 | 11篇 |
1985年 | 11篇 |
1984年 | 10篇 |
1983年 | 9篇 |
1982年 | 12篇 |
1980年 | 8篇 |
1979年 | 9篇 |
1978年 | 10篇 |
1977年 | 7篇 |
1976年 | 7篇 |
1975年 | 11篇 |
1973年 | 13篇 |
1972年 | 10篇 |
1971年 | 11篇 |
1970年 | 7篇 |
1968年 | 11篇 |
排序方式: 共有1870条查询结果,搜索用时 15 毫秒
1.
Emma Carpenter Bethany G. Everett Madelyne Z. Greene Sadia Haider C. Emily Hendrick Jenny A. Higgins 《Social work in health care》2020,59(3):180-198
ABSTRACTSexual minority women (SMW) face both increased risk for unintended pregnancy and barriers to achieving wanted pregnancy, but little research investigates SMW’s pregnancy desires. To fill this gap, we conducted five focus groups and 11 in-depth interviews with 20-30-year-old SMW in three US cities. Findings highlight that the heteronormative pregnancy planning paradigm lacks salience for SMW. While some SMW clearly wish to avoid pregnancy, many others are unsure, and factors influencing this uncertainty include relationship context, anticipating logistical barriers, and discord between queer identity and pregnancy. 相似文献
2.
Ahmad Habeeb Hattab Dala Ali Alani Bassam Abdul Rasool Hassan Azyyati Mohd Suhaimi Ali Haider Mohammed 《Osong Public Health and Research Perspectives》2020,11(6):373
ObjectivesThis study aimed to assess medication use in pregnant women in Malaysia by measuring use, knowledge, awareness, and beliefs about medications.MethodsThis was an observational, cross-sectional study involving a total of 447 pregnant women who attended the Obstetrics and Gynecology Clinic, Hospital Kuala Lumpur (HKL), Malaysia. A validated, self-administered questionnaire was used to collect participant data.ResultsMost of pregnant women had taken medication during pregnancy and more than half of them (52.8%) showed a poor level of knowledge about the medication use during pregnancy. Eighty-three percent had a poor level of awareness and 56.5% had negative beliefs. Age and education level were significantly associated with the level of knowledge regarding medication use during pregnancy. Multiparous pregnant women, and pregnant women from rural areas were observed to have a higher level of awareness compared with those who lived in urban areas. Use of medication during pregnancy was determined to be significantly associated with education level, and race.ConclusionAlthough there was prevalent use of medication among pregnant women, many had negative beliefs, and insufficient knowledge and awareness about the risks of taking medication during pregnancy. Several sociodemographic characteristics were significantly associated with the use (race and education level), level of knowledge (age and education level), awareness (parity and place of residence), and beliefs (race, education level, and occupation status) towards medication use during pregnancy. 相似文献
3.
4.
Shahid Ahmed MD PhD FRCPC Sukanya Pati MD Duc Le MD MSc FRCPC Kamal Haider MD Nayyar Iqbal MD FRCP 《Journal of surgical oncology》2020,122(2):144-154
Over the past two decades, gene expression profiling of breast cancer has emerged as an important tool in early-stage breast cancer management. The approach provides important information on underlying biological mechanisms, breast cancer classification, future risk potential of developing recurrent metastatic disease, and provides beneficial clues for adjuvant chemotherapy in hormone receptor (HR) positive breast cancer. Of the commercially available genomic tests for breast cancer, the prognostic and predictive value of 21-gene recurrence score tests have been validated using both retrospective data and prospective clinical trials. In this paper, we reviewed the current evidence on 21-gene expression profiles for HR-positive HER2-negative early-stage breast cancer management. We show that current evidence supports endocrine therapy alone as an appropriate adjuvant systemic therapy for approximately 70% of women with HR-positive, HER2-negative, node-negative breast cancer. Evolving evidence also suggests that 21-gene recurrence scores have predictive values for node-positive breast cancer and that chemotherapy can be avoided in more than half of women with nodes 1 to 3 positive HR-positive breast cancer. Furthermore, retrospective data also supports the predictive role of 21-gene recurrence scores for adjuvant radiation therapy. A prospective trial in this area is ongoing. 相似文献
5.
6.
7.
8.
Haider A. Mejbel Kelly C. Nelson Dinesh Pradhan Doina Ivan Michael Zaleski Priyadharsini Nagarajan Michael T. Tetzlaff Jonathan L. Curry Carlos A. Torres-Cabala Victor G. Prieto Phyu P. Aung 《Journal of cutaneous pathology》2020,47(1):36-46
We report two cases of combined cutaneous tumors composed of melanoma and carcinoma. The first tumor presented as a 5-mm pink-blue macule over the right zygomatic arch in an 85-year-old man. Shave biopsy and immunohistochemical studies revealed that the tumor was composed of melanoma (highlighted by SOX10 and MART-1, with high Ki-67 proliferative index) intermixed with nodular basal cell carcinoma (highlighted by pan-cytokeratin and Ber-EP4). The neoplastic melanocytes were confined to the basal cell carcinoma nodules, and a diagnosis of combined melanoma in situ and basal cell carcinoma was rendered. After therapeutic excision, the patient was disease-free at 9 months after the initial diagnosis. The second tumor presented as a 6-mm pink-brown crusted papule on the right forehead in an 89-year-old man. Shave biopsy and immunohistochemical studies revealed that the tumor was composed of malignant melanoma (MM) (highlighted by S100 and MART-1) intermixed with squamous cell carcinoma (SCC) (highlighted by cytokeratin and p63), and a diagnosis of combined MM-SCC was rendered. These two cases highlight the importance of recognizing these rare types of melanocytic-epithelial cutaneous neoplasms to arrive at an accurate diagnosis that may inform appropriate disease stage and therapy. 相似文献
9.
10.
York Pei Young-Hwan Hwang John Conklin Jamie L. Sundsbak Christina M. Heyer Winnie Chan Kairong Wang Ning He Anand Rattansingh Mostafa Atri Peter C. Harris Masoom A. Haider 《Journal of the American Society of Nephrology : JASN》2015,26(3):746-753
The clinical use of conventional ultrasonography (US) in autosomal dominant polycystic kidney disease (ADPKD) is currently limited by reduced diagnostic sensitivity, especially in at-risk subjects younger than 30 years of age. In this single-center prospective study, we compared the diagnostic performance of MRI with that of high-resolution (HR) US in 126 subjects ages 16–40 years born with a 50% risk of ADPKD who underwent both these renal imaging studies and comprehensive PKD1 and PKD2 mutation screening. Concurrently, 45 healthy control subjects without a family history of ADPKD completed the same imaging protocol. We analyzed 110 at-risk subjects whose disease status was unequivocally defined by molecular testing and 45 unaffected healthy control subjects. Using a total of >10 cysts as a test criterion in subjects younger than 30 years of age, we found that MRI provided both a sensitivity and specificity of 100%. Comparison of our results from HR US with those from a previous study of conventional US using the test criterion of a total of three or more cysts found a higher diagnostic sensitivity (approximately 97% versus approximately 82%) with a slightly decreased specificity (approximately 98% versus 100%) in this study. Similar results were obtained in test subjects between the ages of 30 and 40 years old. These results suggest that MRI is highly sensitive and specific for diagnosis of ADPKD. HR US has the potential to rival the diagnostic performance of MRI but is both center- and operator-dependent. 相似文献