全文获取类型
收费全文 | 2431篇 |
免费 | 187篇 |
国内免费 | 9篇 |
专业分类
耳鼻咽喉 | 74篇 |
儿科学 | 56篇 |
妇产科学 | 40篇 |
基础医学 | 273篇 |
口腔科学 | 59篇 |
临床医学 | 179篇 |
内科学 | 505篇 |
皮肤病学 | 114篇 |
神经病学 | 100篇 |
特种医学 | 154篇 |
外科学 | 461篇 |
综合类 | 64篇 |
预防医学 | 122篇 |
眼科学 | 78篇 |
药学 | 127篇 |
中国医学 | 11篇 |
肿瘤学 | 210篇 |
出版年
2023年 | 18篇 |
2022年 | 25篇 |
2021年 | 91篇 |
2020年 | 55篇 |
2019年 | 61篇 |
2018年 | 81篇 |
2017年 | 58篇 |
2016年 | 70篇 |
2015年 | 55篇 |
2014年 | 89篇 |
2013年 | 124篇 |
2012年 | 186篇 |
2011年 | 176篇 |
2010年 | 116篇 |
2009年 | 74篇 |
2008年 | 142篇 |
2007年 | 159篇 |
2006年 | 156篇 |
2005年 | 148篇 |
2004年 | 135篇 |
2003年 | 89篇 |
2002年 | 81篇 |
2001年 | 47篇 |
2000年 | 33篇 |
1999年 | 19篇 |
1998年 | 16篇 |
1997年 | 8篇 |
1996年 | 14篇 |
1995年 | 16篇 |
1994年 | 8篇 |
1993年 | 9篇 |
1992年 | 26篇 |
1991年 | 23篇 |
1990年 | 17篇 |
1989年 | 23篇 |
1988年 | 19篇 |
1987年 | 13篇 |
1986年 | 11篇 |
1985年 | 18篇 |
1984年 | 19篇 |
1983年 | 13篇 |
1982年 | 10篇 |
1981年 | 5篇 |
1980年 | 10篇 |
1979年 | 13篇 |
1978年 | 6篇 |
1975年 | 4篇 |
1974年 | 6篇 |
1973年 | 5篇 |
1970年 | 6篇 |
排序方式: 共有2627条查询结果,搜索用时 31 毫秒
1.
Anand Rajan Peerapol Wangrattanapranee Jonathan Kessler Trilokesh Dey Kidambi James H Tabibian 《World journal of gastrointestinal surgery》2022,14(4):286-303
Gastrostomy tube placement is a procedure that achieves enteral access for nutrition, decompression, and medication administration. Preprocedural evaluation and selection of patients is necessary to provide optimal benefit and reduce the risk of adverse events (AEs). Appropriate indications, contraindications, ethical considerations, and comorbidities of patients referred for gastrostomy placement should be weighed and balanced. Additionally, endoscopist should consider either a transoral or transabdominal approach is appropriate, and radiologic or surgical gastrostomy tube placement is needed. However, medical history, physical examination, and imaging prior to the procedure should be considered to tailor the appropriate approach and reduce the risk of AEs. 相似文献
2.
3.
4.
5.
Mostly, collagen is obtained from mammalian sources, but its use is limited because of high cost and various allergic reactions. In this review, different alternative sources of collagen were explored and methods for isolation and peptide generations are summarized. Bioactive peptides are short sequences of 2–20 amino acid residues with positive effect on human health. This review summarizes various biological activities of sea food derived peptides/hydrolysates includes antioxidant, inflammatory, antifreeze, angiotension-I converting enzyme (ACE-I) inhibition, antimicrobial, antiaging, wound healing and anticoagulant activities. Moreover, this review also highlights the therapeutic potential and importance of sea-food derived peptides in various pharmaceutical, biomedical, food and cosmetic industries. This review also proposes biological solution for utilization of seafood derived waste in the development of collagen-based food ingredients that is otherwise cause environmental pollution. 相似文献
6.
7.
8.
Roopa Rajan MD Laura Brennan PhD Bastiaan R. Bloem MD PhD Nabila Dahodwala MD Joan Gardner RN BSN Jennifer G. Goldman MD MS David A. Grimes MD Robert Iansek PhD Norbert Kovács MD PhD Jennifer McGinley PhD Sotirios A. Parashos MD PhD Maria E.P. Piemonte PT PhD Carsten Eggers MD 《Movement disorders》2020,35(9):1509-1531
9.
Simone F. Carron Mujun Sun Sandy R. Shultz Ramesh Rajan 《The Journal of comparative neurology》2020,528(2):175-198
Traumatic brain injury (TBI) can result in excitation: inhibition imbalance, as well as a range of chronic neurological deficits. However, how TBI affects different interneurons, and how this relates to behavioral abnormalities, remains poorly understood. This study examined the effects of a mixed diffuse-focal model of TBI, the lateral fluid percussion injury (LFPI), on interneurons, 8 weeks post-TBI in rats. Brains were labeled with antibodies against calbindin, parvalbumin, calretinin, neuropeptide Y, and somatostatin, and the number of interneurons were assessed in the cortex and hippocampus following LFPI. LFPI caused a reduction in the numbers of interneurons mediating both perisomatic and dendritic inhibition in the somatosensory cortex. In hippocampus, there were heterogenous changes in the number of interneurons while motor cortex, showed no obvious loss in any of the subsets of interneurons after TBI. In parallel to the investigations of changes in the number of interneurons, we also investigated the long-term behavioral consequences of LFPI. Behaviorally, rats given an LFPI displayed transient reduction in performance in motor tasks and were significantly impaired in reversal learning in the water maze task post-TBI. We also report here progressive neurodegeneration in cortex and hippocampus indicated by Fluoro-Jade C in the different brain areas examined after injury. Our findings suggest differential vulnerability of inhibitory neurons to LFPI in the different brain areas examined after injury. These data will aid in evaluation of new treatments for TBI and help target specific neuronal subtypes as a function of injury time and type. 相似文献
10.
Neil B. Marya Patrick D. Powers Larissa Fujii-Lau Barham K. Abu Dayyeh Ferga C. Gleeson Shigao Chen Zaiyang Long David M. Hough Vinay Chandrasekhara Prasad G. Iyer Elizabeth Rajan William Sanchez Tarek Sawas Andrew C. Storm Kenneth K. Wang Michael J. Levy 《Gastrointestinal endoscopy》2021,93(5):1121-1130.e1