Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany

European Archives of Oto-Rhino-Laryngology - Recent reports indicate an increase in the prevalence of Warthin’s tumours (adenolymphoma) with percentages which exceed that of pleomorphic...     

VIROLOGICAL AND SEROLOGICAL DIAGNOSIS OF RABIES IN BATS FROM AN URBAN AREA IN THE BRAZILIAN AMAZON

The outbreaks of rabies in humans transmitted by Desmodus rotundus in 2004 and 2005, in the northeast of the Brazilian State of Para, eastern Amazon basin, made this a priority area for studies on this zoonosis. Given this, the present study provides data on this phenomenon in an urban context, in order to assess the possible circulation of the classic rabies virus (RABV) among bat species in Capanema, a town in the Amazon basin. Bats were collected, in 2011, with mist nets during the wet and dry seasons. Samples of brain tissue and blood were collected for virological and serological survey, respectively. None of the 153 brain tissue samples analyzed tested positive for RABV infection, but 50.34% (95% CI: 45.67-55.01%) of the serum samples analyzed were seropositive. Artibeus planirostris was the most common species, with a high percentage of seropositive individuals (52.46%, 95% CI: 52.31 52.60%). Statistically, equal proportions of seropositive results were obtained in the rainy and dry seasons (c² = 0.057, d.f. = 1, p = 0.88). Significantly higher proportions of males (55.96%, 95% CI: 48.96-62.96%) and adults (52.37%, 95% CI: 47.35-57.39%) were seropositive. While none of the brain tissue samples tested positive for infection, the high proportion of seropositive specimens indicates that RABV may be widespread in this urban area.     

Effect of light-curing methods on resin cement Knoop hardness at different depths

This study evaluated, using Knoop hardness test, the polymerization depth of Rely-X dual-cured resin cement activated by chemical reaction alone (control group) or by chemical/physical mode with light curing through a 1.5-mm-thick ceramic layer (HeraCeram). Bovine incisors had their buccal surface flattened and hybridized. On this surface, a rubber mould (5 mm diameter; 1 mm high) was bulk filled with cement. Either a polyester strip or a 1.5-mm-thick disc of the veneering material was seated over this set. Light curing was performed with either conventional halogen light (QTH; XL2500) for 40 s, light-emitting diode (LED; Ultrablue Is) for 40 s or xenon plasma arc (PAC; Apollo 95E) for 3 s. In a control group, cement setting occurred by chemical reaction alone. After storage dry in dark (24 h/37 masculineC), the specimens (n=5) were sectioned for hardness (KHN) measurements at three depths in a microhardness tester (50 gf load/15 s). Data were submitted to ANOVA and Tukey's test (a = 0.05). Rely-X cement presented higher Knoop hardness values when the QTH and LED LCUs were used, compared to the control group and PAC. Light curing with PAC resulted in lower hardness compared to the control group. Cement hardness was significantly lower in deeper regions.     

Shear bond strength of a ceramic to Co-Cr alloys

STATEMENT OF PROBLEM: Different combinations of Co-Cr alloys bonded to ceramic have been used in dentistry; however, the bond strength of ceramic to metal can vary because of different compositions of these alloys. PURPOSE: The purpose of this study was to evaluate the shear bond strength of a dental ceramic to 5 commercially available Co-Cr alloys. MATERIAL AND METHODS: Five Co-Cr alloys (IPS d.SIGN 20, IPS d.SIGN 30, Remanium 2000, Heranium P, and Wirobond C) were tested and compared to a control group of an Au-Pd alloy (Olympia). Specimen disks, 5 mm high and 4 mm in diameter, were fabricated with the lost-wax technique. Sixty specimens were prepared using opaque and dentin ceramics (VITA Omega 900), veneered, 4 mm high and 4 mm in diameter, over the metal specimens (n=10). The shear bond strength test was performed in a universal testing machine with a crosshead speed of 0.5 mm/min. After shear bond testing, fracture surfaces were evaluated in a stereomicroscope under x25 magnification. Ultimate shear bond strength (MPa) data were analyzed with 1-way ANOVA and the Tukey HSD test (alpha =.05). RESULTS: The mean (SD) bond strengths (MPa) were: 61.4 (7.8) for Olympia; 94.0 (18.9) for IPS 20; 96.8 (10.2) for IPS 30; 75.1 (12.4) for Remanium; 71.2 (14.3) for Heranium P; and 63.2 (10.9) for Wirobond C. Mean bond strengths for IPS 20 and IPS 30 were not significantly different, but were significantly (P<.001) higher than mean bond strengths for the other 4 alloys, which were not significantly different from each other. CONCLUSIONS: Bond strength of a dental ceramic to a Co-Cr alloy is dependent on the alloy composition.     

Antibodies to periodontal pathogens and coronary artery calcification in type 1 diabetic and nondiabetic subjects

Background and Objective:  The aim of this study was to examine whether serum immunoglobulin G (IgG) levels to Porphyromonas gingivalis and Actinobacillus actinomycetemcomitans are higher in type 1 diabetic patients than in controls and are associated with coronary artery calcification, a measure of atherosclerosis.
Material and Methods:  One-hundred and ninety nine type 1 diabetic patients (mean age 38 ± 4 years) and 201 age- and gender-matched nondiabetic subjects had coronary artery calcification, as measured by electron beam computed tomography. Serum IgG levels to P. gingivalis W50 and to A. actinomycetemcomitans HK1651 whole cells were measured by enzyme-linked immunosorbent assay.
Results:  A similar proportion of diabetic patients (29%) and controls (31%, p  = 0.7) had elevated serum IgG to periodontal bacteria, defined as being above the median antibody level for both microorganisms. Elevated antibody levels were associated with higher systolic blood pressure ( p  = 0.02) and an increased odds of coronary artery calcification in all subjects combined (odds ratio = 1.7, p  = 0.047) and in diabetic subjects examined separately (odds ratio = 2.01, p  = 0.027). Association of serum IgG levels with coronary artery calcification was independent of social class, lipids and antibody levels to other microorganisms, but not systolic blood pressure (odds ratio = 1.4, p  = 0.1 on adjustment for blood pressure). There was no association between serum IgG level and vascular endothelial function.
Conclusion:  Elevated levels of serum IgG to P. gingivalis and A. actinomycetemcomitans are associated with coronary artery atherosclerosis. This may reflect a direct role for periodontal infection or a role for the host response to infection in coronary atherosclerosis, particularly in patients with type 1 diabetes.     

Clinical wear of overdenture ball attachments after 1, 3 and 8 years

Objectives: Implant‐supported overdentures have become the treatment of choice in restoring complete edentulism, but the types of attachment to assure durable retention are a subject of debate. Ball attachments were reported as a simple treatment, but wear of components was responsible for a decrease in retention. The aim of this retrospective study was to measure the wear of the ball abutment or patrix after three different periods of clinical wear. Material and methods: Sixty‐nine specimens of three groups of patrix that were in use for a mean of 12.3 months (group A), 39 months (group B) and 95.6 months (group C) were retrieved from 35 patients and measured on a coordinate measuring machine equipped with a touch trigger probe. Ten unused ball abutments were added as a control (group D). The patrix diameters and any deviation from circularity in different axes were measured. Results: The diameters of groups A, B and C were significantly different from that of group D (control). No statistically significant differences were found between diameter and circularity variations between groups B and C. The maximal amount of diameter reduction was limited to approximately 30 μm, and 90% of diameter loss at the equator due to wear was reached in group B. Conclusion: One, 3 and 8 years of clinical wear reduced significantly the diameters of the ball abutments tested, and the maximal amount of wear was reached after 3 years of clinical use. To cite this article:
Fromentin O, Lassauzay C, Nader SA, Feine J, Albuquerque RF Jr. Clinical wear of overdenture ball attachments after 1, 3 and 8 years.
Clin. Oral Impl. Res. 22 , 2011; 1270–1274.
doi: 10.1111/j.1600‐0501.2010.02102.x     

Mixed-integer quadratic programming for automatic walking footstep placement,duration, and rotation

This paper presents a mixed-integer model predictive controller for walking. In the proposed scheme, mixed-integer quadratic programs (MIQP) are solved online to simultaneously decide center of mass jerks, footsteps positions, durations, and rotations while respecting actuation, geometry, and contact constraints. Most walking controllers require preplanned footstep rotations to avoid dealing with the nonlinearity introduced by foot rotation decision. The main contribution of this work is an optimization formulation where feet rotations are automatically planned to attain a reference speed rotation. Finally, simulation results are shown to present and discuss the capabilities of the proposed formulation.     

Immunomodulation and protection induced by DNA-hsp65 vaccination in an animal model of arthritis

We described a prophylactic and therapeutic effect of a DNA vaccine encoding the Mycobacterium leprae 65-kDa heat shock protein (DNA-hsp65) in experimental murine tuberculosis. However, high homology of the vaccine to the corresponding mammalian hsp60, together with the CpG motifs in the plasmidial vector, could trigger or exacerbate an autoimmune disease. In the present study, we evaluate the potential of DNA-hsp65 vaccination to induce or modulate arthritis in mice genetically selected for acute inflammatory reaction (AIR), either maximal (AIRmax) or minimal (AIRmin). Mice immunized with DNA-hsp65 or injected with the corresponding DNA vector (DNAv) developed no arthritis, whereas pristane injection resulted in arthritis in 62% of AIRmax mice and 7.3% of AIRmin mice. Administered after pristane, DNA-hsp65 downregulated arthritis induction in AIRmax animals. Levels of interleukin (IL)-12 were significantly lower in mice receiving pristane plus DNA-hsp65 or DNAv than in mice receiving pristane alone. However, when mice previously injected with pristane were inoculated with DNA-hsp65 or DNAv, the protective effect was significantly correlated with lower IL-6 and IL-12 levels and higher IL-10 levels. Our results strongly suggest that DNA-hsp65 has no arthritogenic potential and is actually protective against experimentally induced arthritis in mice.