首页 | 本学科首页   官方微博 | 高级检索  
文章检索
  按 检索   检索词:      
出版年份:   被引次数:   他引次数: 提示:输入*表示无穷大
  收费全文   4879804篇
  免费   386087篇
  国内免费   15026篇
耳鼻咽喉   69089篇
儿科学   157835篇
妇产科学   130261篇
基础医学   731298篇
口腔科学   136374篇
临床医学   447147篇
内科学   882007篇
皮肤病学   117097篇
神经病学   408443篇
特种医学   193099篇
外国民族医学   972篇
外科学   736784篇
综合类   138467篇
一般理论   2849篇
预防医学   406654篇
眼科学   115321篇
药学   350646篇
  21篇
中国医学   12571篇
肿瘤学   243982篇
  2021年   44626篇
  2019年   58395篇
  2018年   74849篇
  2017年   57344篇
  2016年   63403篇
  2015年   76037篇
  2014年   110953篇
  2013年   177045篇
  2012年   141387篇
  2011年   149680篇
  2010年   131045篇
  2009年   130977篇
  2008年   134607篇
  2007年   144626篇
  2006年   151942篇
  2005年   146076篇
  2004年   146794篇
  2003年   136439篇
  2002年   124894篇
  2001年   196639篇
  2000年   193181篇
  1999年   171954篇
  1998年   70110篇
  1997年   64787篇
  1996年   62876篇
  1995年   63799篇
  1994年   57748篇
  1993年   53534篇
  1992年   128197篇
  1991年   123331篇
  1990年   118681篇
  1989年   115194篇
  1988年   106028篇
  1987年   104157篇
  1986年   98257篇
  1985年   95698篇
  1984年   77497篇
  1983年   68052篇
  1982年   51190篇
  1981年   47268篇
  1980年   44271篇
  1979年   67363篇
  1978年   52727篇
  1977年   46151篇
  1976年   42766篇
  1975年   43684篇
  1974年   48695篇
  1973年   46699篇
  1972年   43798篇
  1971年   40477篇
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
American Indian and Alaska Native (AIAN) individuals are diverse culturally and geographically but share a high prevalence of chronic illness, largely because of obstacles to high-quality health care. The authors comprehensively examined cancer incidence and mortality among non-Hispanic AIAN individuals, compared with non-Hispanic White individuals for context, using population-based data from the National Cancer Institute, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries. Overall cancer rates among AIAN individuals were 2% higher than among White individuals for incidence (2014 through 2018, confined to Purchased/Referred Care Delivery Area counties to reduce racial misclassification) but 18% higher for mortality (2015 through 2019). However, disparities varied widely by cancer type and geographic region. For example, breast and prostate cancer mortality rates are 8% and 31% higher, respectively, in AIAN individuals than in White individuals despite lower incidence and the availability of early detection tests for these cancers. The burden among AIAN individuals is highest for infection-related cancers (liver, stomach, and cervix), for kidney cancer, and for colorectal cancer among indigenous Alaskans (91.3 vs. 35.5 cases per 100,000 for White Alaskans), who have the highest rates in the world. Steep increases for early onset colorectal cancer, from 18.8 cases per 100,000 Native Alaskans aged 20–49 years during 1998 through 2002 to 34.8 cases per 100,000 during 2014 through 2018, exacerbated this disparity. Death rates for infection-related cancers (liver, stomach, and cervix), as well as kidney cancer, were approximately two-fold higher among AIAN individuals compared with White individuals. These findings highlight the need for more effective strategies to reduce the prevalence of chronic oncogenic infections and improve access to high-quality cancer screening and treatment for AIAN individuals. Mitigating the disparate burden will require expanded financial support of tribal health care as well as increased collaboration and engagement with this marginalized population.  相似文献   
2.
The analysis of mismatch repair proteins in solid tissue is the standard of care (SoC) for the microsatellite instability (MSI) characterization in endometrial cancer (EC). Uterine aspirates (UAs) or circulating-DNA (cfDNA) samples capture the intratumor heterogeneity and provide a more comprehensive and dynamic molecular diagnosis. Thus, MSI analysis by droplet-digital PCR (ddPCR) in UAs and cfDNA can provide a reliable tool to characterize and follow-up the disease. The UAs, paraffin-embedded tumor tissue (FFPE) and longitudinal plasma samples from a cohort of 90 EC patients were analyzed using ddPCR panel and compared to the SoC. A high concordance (96.67%) was obtained between the analysis of MSI markers in UAs and the SoC. Three discordant cases were validated as unstable by ddPCR on FFPE samples. Besides, a good overall concordance (70.27%) was obtained when comparing the performance of the ddPCR assay on UAs and cfDNA in high-risk tumors. Importantly, our results also evidenced the value of MSI analysis to monitor the disease evolution. MSI evaluation in minimally invasive samples shows great accuracy and sensitivity and provides a valuable tool for the molecular characterization and follow-up of endometrial tumors, opening new opportunities for personalized management of EC.  相似文献   
3.
4.
5.
AIDS and Behavior - Although misperceived norms often drive personal health behaviors, we do not know about this phenomenon in the context of antiretroviral therapy (ART) adherence. We conducted a...  相似文献   
6.
Spindler  L.  Alam  A.  Fathallah  N.  Rentien  A.-L.  Draullette  M.  Pommaret  E.  Thierry  M.-L.  Mituialy  A. El  Abbes  L.  Aubert  M.  Benfredj  P.  Far  E. Safa  Beaussier  H.  de Parades  V. 《Techniques in coloproctology》2022,26(2):143-146
Techniques in Coloproctology - The aim of our study was to assess the efficacy of sinus laser therapy (SiLaT) for the treatment of pilonidal disease. All adult patients treated with SiLaT in our...  相似文献   
7.
Coates  Laura C.  Mease  Philip  Kronbergs  Andris  Helt  Cameron  Sandoval  David  Park  So Young  Combe  Bernard  Nash  Peter  Deodhar  Atul 《Clinical rheumatology》2022,41(10):3035-3047
Clinical Rheumatology - To evaluate the three-year efficacy and safety of ixekizumab with and without concomitant conventional synthetic disease-modifying antirheumatic drug (csDMARD) use in...  相似文献   
8.
Clinical Rheumatology - This study aimed to assess treatment patterns and frequency of inadequate response associated with advanced therapy initiation among patients with ankylosing spondylitis...  相似文献   
9.
The International Journal of Cardiovascular Imaging - Global longitudinal strain (GLS) has proven to be a powerful prognostic marker in various patient populations, but the prognostic value of...  相似文献   
10.
The International Journal of Cardiovascular Imaging - This study investigated the impact of bicuspid aortic valve (BAV) on valve morphology and motion as well as proximal and aortic hemodynamics...  相似文献   
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号