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Richardson Matthew L. Guérit François Gransier Robin Wouters Jan Carlyon Robert P. Middlebrooks John C. 《Journal of the Association for Research in Otolaryngology》2022,23(4):491-512
Journal of the Association for Research in Otolaryngology - Cochlear implant (CI) users show limited sensitivity to the temporal pitch conveyed by electric stimulation, contributing to impaired... 相似文献
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Scott R. Bauer MD ScM Peggy M. Cawthon PhD MPH Kristine E. Ensrud MD Anne M. Suskind MD MS John C. Newman MD PhD Howard A. Fink MD MPH Kaiwei Lu MS Rebecca Scherzer PhD Andrew R. Hoffman MD Kenneth Covinsky MD Lynn M. Marshall ScD For the Osteoporotic Fractures in Men Research Group 《Journal of the American Geriatrics Society》2022,70(4):1082-1094
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Shareen Forbes Anneliese J. Flatt Denise Bennett Robert Crookston Mirka Pimkova Linda Birtles Andrew Pernet Ruth C. Wood Keith Burling Peter Barker Claire Counter Alistair Lumb Pratik Choudhary Martin K. Rutter Miranda Rosenthal Andrew Sutherland John Casey Paul Johnson James A. M. Shaw 《American journal of transplantation》2022,22(1):154-164
The UK islet allotransplant program is nationally funded to deliver one or two transplants over 12 months to individuals with type 1 diabetes and recurrent severe hypoglycemia. Analyses were undertaken 10 years after program inception to evaluate associations between transplanted mass; single versus two transplants; time between two transplants and graft survival (stimulated C-peptide >50 pmol/L) and function. In total, 84 islet transplant recipients were studied. Uninterrupted graft survival over 12 months was attained in 23 (68%) single and 47 (94%) (p = .002) two transplant recipients (separated by [median (IQR)] 6 (3–8) months). 64% recipients of one or two transplants with uninterrupted function at 12 months sustained graft function at 6 years. Total transplanted mass was associated with Mixed Meal Tolerance Test stimulated C-peptide at 12 months (p < .01). Despite 1.9-fold greater transplanted mass in recipients of two versus one islet infusion (12 218 [9291–15 417] vs. 6442 [5156–7639] IEQ/kg; p < .0001), stimulated C-peptide was not significantly higher. Shorter time between transplants was associated with greater insulin dose reduction at 12 months (beta ?0.35; p = .02). Graft survival over the first 12 months was greater in recipients of two versus one islet transplant in the UK program, although function at 1 and 6 years was comparable. Minimizing the interval between 2 islet infusions may maximize cumulative impact on graft function. 相似文献
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Yaghjyan Lusine Darville Lancia N. F. Cline Jayden Martinez Yessica C. Rich Shannan Austin-Datta Rebecca J. Koomen John M. Tworoger Shelley S. Egan Kathleen M. 《Cancer causes & control : CCC》2022,33(2):279-291
Cancer Causes & Control - Circulating estrogens are an established risk factor for postmenopausal breast cancer (BCa). We describe the distribution of urinary estrogens, their metabolites, and... 相似文献
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Ganz Patricia A. Bandos Hanna Geyer Charles E. Robidoux André Paterson Alexander H. G. Polikoff Jonathan Baez-Diaz Luis Brufsky Adam M. Fehrenbacher Louis Parsons Ann W. Ward Patrick J. Provencher Louise Hamm John T. Stella Philip J. Carolla Robert L. Margolese Richard G. Shibata Henry R. Perez Edith A. Wolmark Norman 《Breast cancer research and treatment》2022,192(1):153-161
Breast Cancer Research and Treatment - The NSABP B-36 compared four cycles of doxorubicin and cyclophosphamide (AC) with six cycles of 5-fluorouracil, epirubicin, and cyclophosphamide (FEC-100) in... 相似文献
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Brain Topography - Accurate cortical source localization of event-related potentials (ERPs) requires using realistic head models constructed from the participant’s structural magnetic... 相似文献