全文获取类型
收费全文 | 7961篇 |
免费 | 417篇 |
国内免费 | 34篇 |
专业分类
耳鼻咽喉 | 62篇 |
儿科学 | 154篇 |
妇产科学 | 147篇 |
基础医学 | 1001篇 |
口腔科学 | 97篇 |
临床医学 | 1019篇 |
内科学 | 1967篇 |
皮肤病学 | 219篇 |
神经病学 | 739篇 |
特种医学 | 118篇 |
外科学 | 1040篇 |
综合类 | 41篇 |
一般理论 | 2篇 |
预防医学 | 640篇 |
眼科学 | 116篇 |
药学 | 617篇 |
中国医学 | 20篇 |
肿瘤学 | 413篇 |
出版年
2023年 | 50篇 |
2022年 | 22篇 |
2021年 | 184篇 |
2020年 | 110篇 |
2019年 | 221篇 |
2018年 | 322篇 |
2017年 | 185篇 |
2016年 | 198篇 |
2015年 | 232篇 |
2014年 | 210篇 |
2013年 | 371篇 |
2012年 | 677篇 |
2011年 | 717篇 |
2010年 | 344篇 |
2009年 | 267篇 |
2008年 | 556篇 |
2007年 | 571篇 |
2006年 | 531篇 |
2005年 | 516篇 |
2004年 | 452篇 |
2003年 | 452篇 |
2002年 | 410篇 |
2001年 | 70篇 |
2000年 | 70篇 |
1999年 | 57篇 |
1998年 | 46篇 |
1997年 | 25篇 |
1996年 | 42篇 |
1995年 | 27篇 |
1994年 | 23篇 |
1993年 | 18篇 |
1992年 | 38篇 |
1991年 | 22篇 |
1990年 | 26篇 |
1989年 | 18篇 |
1988年 | 32篇 |
1987年 | 27篇 |
1986年 | 25篇 |
1985年 | 19篇 |
1984年 | 19篇 |
1982年 | 16篇 |
1981年 | 14篇 |
1980年 | 14篇 |
1979年 | 12篇 |
1976年 | 12篇 |
1975年 | 15篇 |
1973年 | 12篇 |
1972年 | 15篇 |
1968年 | 16篇 |
1967年 | 13篇 |
排序方式: 共有8412条查询结果,搜索用时 93 毫秒
1.
2.
3.
4.
5.
Alazne Belar Maria Arantzamendi Alfredo Rodríguez-Núñez Yolanda Santesteban Marina Martinez Mario López-Saca Sara Consigli Jesús López-Fidalgo Carlos Centeno 《Journal of pain and symptom management》2019,57(3):627-634
Context
Demoralization is a state of existential distress in patients with advanced illness, typically with coping difficulties, feelings of loss of sense, and purpose in life and despair, among other things. The New Demoralization Scale (DS-II) is an evaluation tool for this syndrome, which has recently been reformulated on a shorter scale.Objectives
The objective of this study was to obtain a Spanish version of the DS-II and to assess its psychometric properties in advanced cancer patients in Spain and a number of Latin American countries.Methods
Following a translation–back translation process, a validation study and a confirmatory analysis using structural equation models with their corresponding latent constructs were undertaken. Patients completed the DS-II in Spanish (DS-II (es)), the Hospital Anxiety and Depression Scale, and the Edmonton Symptom Assessment System–revised. Reliability was studied according to internal consistency; construct validity and concurrent validity with the Hospital Anxiety and Depression Scale and the Edmonton Symptom Assessment System–revised; discriminant validity using the Karnofsky Performance Status scale; and feasibility, with response ratio and required time. Cutoff points were established, and sensitivity and specificity were studied.Results
The DS-II (es) was obtained. One hundred fifty patients completed the validation study. The confirmatory analysis showed coherence, and all items correlated positively with their subscales and with the overall scale. Cronbach's alpha for the DS-II (es) was 0.88, for the sense and purpose subscale 0.83, and for the coping ability 0.79. Demoralization correlated significantly with emotional distress (rho = 0.73, P < 0.001). The tool distinguished between patients with diverse functional levels (rho = ?0.319, P = 0.001). Cutoff points at 10 and 20 out of 32 were established. The scale showed high sensitivity (81.97%) and specificity (80.90%). The prevalence of demoralization was 33% in our sample.Conclusion
The Spanish version of the new Kissane DS-II demoralization scale has shown to be valid, reliable, and feasible with adequate psychometric properties. 相似文献6.
7.
Oral Nadolol for Children with Infantile Hemangiomas and Sleep Disturbances with Oral Propranolol 下载免费PDF全文
8.
Jesús Florido Catalina de Paco-Matallana M. Soledad Quezada M. Carmen Garrido-Sánchez Carmen Padilla Olga Ocón 《The journal of maternal-fetal & neonatal medicine》2015,28(2):186-189
Objective: The aim of the current study was to determine any relationship between the timing of clamping of the umbilical cord and the lipid levels circulating in umbilical artery and vein.Methods: We studied a clinical trial with systematic assignment in 229 single-fetus full-term deliveries with normal gestational course and spontaneous delivery; out of these, 111 were subjected to early clamping (EC, within 10?s of delivery) and 118 to late clamping (LC, at 2?min). In all cases, total cholesterol (TC), triglycerides (TG), and phospholipids were measured in sera from umbilical artery and vein.Results: TC and TG values were significantly higher in the EC group than in the LC group in both umbilical artery and vein. Comparing values between umbilical artery and vein in the two clamping groups, in the EC group, all studied lipids TC, TG and phospholipids were significantly higher in vein than in artery. In the LC group, only TC was higher in vein.Conclusion: Umbilical cord lipid levels are related to the timing of umbilical cord clamping, finding which is noteworthy, because they are essential component of postnatal development. Our study confirms that delivery acts as an important modifier of fetal lipid levels. 相似文献
9.
10.
José Martínez-Comendador Javier Gualis José Miguel Marcos-Vidal Jonnatan Buber Carlos Esteban Martín Jesús Gomez-Plana Miguel Angel Rodríguez Ignacio Iglesias-Garriz David Alonso Carlos Soria Eva Higuera Miguélez Mario Casta?o 《Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital》2015,42(5):430-437
The customary recommendation is that oral anticoagulation be withdrawn a few months after cryoablation for atrial fibrillation, independently of left atrial mechanical contraction in patients in sinus rhythm. Recently, a 5-fold increase in stroke has been described in sinus-rhythm patients who lack atrial mechanical contraction. One aim of this study was to evaluate the efficacy of oral anticoagulation in preventing postoperative stroke in such patients.This prospective study divided 154 sinus-rhythm patients into 2 groups, depending on the presence (108 patients) or absence (46 patients) of left atrial mechanical contraction at 6 months after surgery, and monitored them annually for 5 years. Those without left atrial contraction were maintained on acenocumarol. The primary endpoint was the occurrence of ischemic stroke.The median follow-up period was 29 ± 16 months; 4 patients (2.5%), all belonging to the group with preserved atrial contraction, had ischemic stroke; the group of patients without left atrial contraction had no episodes of stroke during follow-up. Logistic binary regression analyses showed no evidence of factors independently predictive of stroke.Among anticoagulated patients in sinus rhythm without left atrial contraction, we found the incidence of stroke to be zero. In a small, nonrandomized group such as this, we cannot discount the element of chance, yet we suggest that maintaining anticoagulation might lower the incidence of stroke in this population. 相似文献