Acute leriche syndrome due to paradoxical embolism.

Paradoxical embolism, describing the passage of venous or right-sided cardiac thrombus into the arterial or systemic circulation through patent foramen ovale, is an uncommon cause of acute arterial occlusion. Here, we report acute Leriche syndrome in a young woman attributable to paradoxical embolism. Ischaemia, patent foramen ovale, and venous thrombosis were the triad of evidence for paradoxical embolism.     

Effect of myasthenic IgG on degradation of junctional acetylcholine receptor

We investigated the effect of the lgG from patients with myasthenia gravis (MG) on the degradation of normal rat junctional acetylcholine receptor (AChR) labeled with ¹²⁵l-α-bungarotoxin (BuTx) and calculated the degradation rate (DR). The DR for the lgG from these patients was significantly higher than that from healthy volunteers and patients with other autoimmune diseases. For MG, DR was significantly correlated with the severity of the disease but not with anti-AChR antibody titer. DR was accelerated by lgG from patients with generalized MG whose antibody titers were in the normal range and by lgG from patients with ocular MG. These results indicate that measurement of the DR of junctional AChR in normal rats is more closely correlated with the severity of the disease than is measurement of anti-AChR antibody and that the former is a sensitive and confirmatory method for evaluating MG. © 1993 John Wiley & Sons, Inc.     

类比思维结合创设乐学情境教学在眼科护理实习教学中的应用研究

目的 探讨类比思维结合创设乐学情境教学在眼科护理实习教学中的应用研究。方法 选取2020年10月至2022年1月在空军军医大学第一附属医院西京医院眼科实习的90名护生作为研究对象。按照不同的教学方法分为对照组和观察组,对照组45名护生采用常规教学,观察组45名护生采用类比思维结合创设乐学情境教学。评估两组护生的综合考核成绩、教学效果调查问卷及学生对带教教师的总满意度。采用SPSS 22.0进行t检验和卡方检验。结果 观察组护生的理论知识考核成绩[（85.39±1.57） vs. （84.41±1.34）]、护理技能考核成绩[（87.52±0.04） vs. （82.64±0.05）均高于对照组;观察组护生的眼科护理工作中的用药安全意识、专业兴趣与自主学习性提升、协作组织能力增强、独立思考和自主学习能力提升、达到多学科知识融会贯通的目的、信息量与知识面改善、临床思维沟通交流能力增强、理论知识灵活应用、动手操作能力提高、培养创新意识各个方面评分均优于对照组;带教教师对学生学习态度、语言表达、呼唤沟通能力、独立解决问题能力等方面的评价,观察组高于对照组（P <0.05）。结论 类比思维结合创设乐学情境教学能提高护生的平均考核成绩和护理技能考核成绩,能改善学生对带教教师的满意度。     

Klinefelter综合征患者和双亲对诱变剂敏感性研究

为了解诱变剂对Ｋｌｉｎｅｆｅｌｔｅｒ综合征发生的影响，对Ｋｌｉｎｅｆｅｌｔｅｒ综合征患者，患者双亲及对照进行丝裂霉素Ｃ，乙醛或乙醇诱导非二倍体，染色体结构畸变及微核观察，发现丝裂霉素Ｃ诱导的患者当色体结构畸变和微核均显著多于对照和双亲，乙醛和乙醇能诱导非二倍体和微核增加，但患者和双亲增加的程度极显著高于对照，提示Ｋｌｉｎｅｆｅｌｔｅｒ综合征患者对于丝裂霉素Ｃ，乙醛和乙醇诱导染色体畸变更敏感。双亲对     

Effects of methylprednisolone on the neural conduction of the motor evoked potentials in spinal cord injured rats

Methylprednisolone(MP), a glucocorticoid steroid, has an anti-inflammatory action and seems to inhibit the formation of oxygen free radicals produced during lipid peroxidation in a spinal cord injury(SCI). However, the effects of MP on the functional recovery after a SCI is controversial. The present study was conducted to determine the effects of MP on the recovery of neural conduction following a SCI. A SCI was produced using the NYU spinal cord impactor. A behavioral test was conducted to measure neurological disorders, and motor evoked potentials (MEPs) were recorded. According to the behavioral test, using BBB locomotor scaling, MP-treated animals showed improved functional recoveries when compared to saline-treated animals. MEP latencies in the MP-treated group were shortened when compared to those in the control group. Peak amplitudes of MEPs were larger in the MP-treated group than those in the control group. The thresholds of MEPs tended to be lower in the MP-treated group than those in the control group. These results suggest that MP may improve functional recovery after a SCI.     

牙用遮色瓷热处理制度的研究

首次选用双相成核剂CaF2 和TiO2 为制备遮色瓷的成核剂 ,以SiO2 —Al2 O3 —K2 O—Na2 O系统为其基质成分 ,采用差热分析仪、扫描电镜和x衍射分析仪等实验手段来探讨本体系遮色瓷制备的热处理制度。结果表明阶梯制度的热处理方式适用于本体系的遮色瓷。瓷粉经过如下的热处理制度 :从室温以 8℃ /min的加热速度升温至 75 0℃保温 1h ,然后再以4℃ /min的升温速度升至 96 0℃ ,保温 2h后冷淬 ,其白榴石晶体的析晶行为良好 ,且晶体尺寸较小 (约 1μm左右 )。该热处理制度的确定为改善遮色瓷与金属的热匹配性和提高遮色瓷的理化性能提供了基础     

顶空气相色谱法测定醋酸烯诺孕酮埋植剂中环氧乙烷的残留量

用顶空气相色谱法测定醋酸烯诺孕酮埋植剂中环氧乙烷的残留量，结果表明，线性试验与精密度良好，平均回收率为99．8％，残留量为0．93％。样品在灭菌后，室温放置3天，其环氧乙烷残留量均在0．0001％以下，符合环氧乙烷残留量应不大于0．001％的规定。表明采用顶空气相色谱法测定醋酸烯诺孕酮理植剂中环氧乙烷残留量，方法简便，结果准确，适用于对该产品中环氧乙烷残留量的检测与控制。     

Phylogeny of Vibrio cholerae based on recA sequence

We sequenced a 705-bp fragment of the recA gene from 113 Vibrio cholerae strains and closely related species. One hundred eighty-seven nucleotides were phylogenetically informative, 55 were phylogenetically uninformative, and 463 were invariant. Not unexpectedly, Vibrio parahaemolyticus and Vibrio vulnificus strains formed out-groups; we also identified isolates which resembled V. cholerae biochemically but which did not cluster with V. cholerae. In many instances, V. cholerae serogroup designations did not correlate with phylogeny, as reflected by recA sequence divergence. This observation is consistent with the idea that there is horizontal transfer of O-antigen biosynthesis genes among V. cholerae strains.     

立体定向治疗中靶心定位的算法

本文介绍了在立体定向放射神经外科中，根据病人配戴头环和ＣＴ定标架作ＣＴ扫描所得的ＣＴ断层图像或配戴ＡＶＭ定位箱做血管造影得到的两张Ｘ光片确定病人颅内病灶的三维坐标的方法。     

MORPHOLOGICAL DIFFERENCES IN HEARTS OF RATS WELL ADAPTED AND POORLY ADAPTED TO CHRONIC HYPOXIA

We carried out an experiment to analyze morphological differences in hearts of rats well adapted and poorly adapted to chronic hypoxia. Male and female Wistar rats, 1 week, 4 weeks and 9 weeks old, were employed on the assumption that adaptive ability was dependent on age and sex. These rats were raised at an altitude of 2,400 m and were kept for 7 to 9 weeks. Control groups were maintained at an altitude of 600 m during the same period of time. Each group consisted of 4 to 6 rats. At the end of the experiment, body weight, heart weight, ratio of heart weight to body weight and hematocrit were measured, and ventricular wall thickness, myocardial fiber diameter, capillary supply and mitochondria were morphometrically studied. Of the 6 experimental groups, the 4-week-old male rats (M2) had the highest body weight, as compared with the other experimental groups. In addition, relative to these other experimental groups, the following features were found for M2. Heart weight was intermediate, heart weight/body weight ratio was low and hematocrit was also low. Ventricular wall thickness was intermediate in the right ventricle (RV) and interventricular septum (IVS) but was thin in the left ventricle (LV). Myocardial fiber diameter was intermediate in the RV, large in the IVS and small in the LV. Capillary supply was intermediate in the RV and dense in the IVS and LV. Mitochondria were small but cristal density and percentage area, estimated from electron micrographs, were found to be high. These data showed that in well developed rats under chronic hypoxia, there is good development of capillary supply with corresponding restriction of cardiac hypertrophy, while hematocrit count and mitochondria are also affected.