全文获取类型
收费全文 | 22321篇 |
免费 | 2187篇 |
国内免费 | 27篇 |
专业分类
耳鼻咽喉 | 384篇 |
儿科学 | 641篇 |
妇产科学 | 607篇 |
基础医学 | 3004篇 |
口腔科学 | 683篇 |
临床医学 | 2947篇 |
内科学 | 4169篇 |
皮肤病学 | 411篇 |
神经病学 | 1756篇 |
特种医学 | 838篇 |
外国民族医学 | 2篇 |
外科学 | 3189篇 |
综合类 | 401篇 |
一般理论 | 13篇 |
预防医学 | 2125篇 |
眼科学 | 406篇 |
药学 | 1534篇 |
3篇 | |
中国医学 | 58篇 |
肿瘤学 | 1364篇 |
出版年
2021年 | 227篇 |
2020年 | 197篇 |
2019年 | 288篇 |
2018年 | 358篇 |
2017年 | 263篇 |
2016年 | 299篇 |
2015年 | 354篇 |
2014年 | 518篇 |
2013年 | 739篇 |
2012年 | 1049篇 |
2011年 | 1148篇 |
2010年 | 631篇 |
2009年 | 535篇 |
2008年 | 940篇 |
2007年 | 974篇 |
2006年 | 1012篇 |
2005年 | 924篇 |
2004年 | 1027篇 |
2003年 | 966篇 |
2002年 | 833篇 |
2001年 | 771篇 |
2000年 | 695篇 |
1999年 | 666篇 |
1998年 | 260篇 |
1997年 | 207篇 |
1996年 | 195篇 |
1995年 | 213篇 |
1994年 | 189篇 |
1993年 | 190篇 |
1992年 | 520篇 |
1991年 | 517篇 |
1990年 | 445篇 |
1989年 | 508篇 |
1988年 | 476篇 |
1987年 | 466篇 |
1986年 | 447篇 |
1985年 | 471篇 |
1984年 | 317篇 |
1983年 | 285篇 |
1982年 | 202篇 |
1981年 | 176篇 |
1979年 | 256篇 |
1978年 | 197篇 |
1977年 | 164篇 |
1976年 | 176篇 |
1974年 | 189篇 |
1973年 | 202篇 |
1972年 | 158篇 |
1971年 | 162篇 |
1970年 | 154篇 |
排序方式: 共有10000条查询结果,搜索用时 78 毫秒
1.
2.
3.
4.
5.
Tarik D. Madni Paul A. Nakonezny Evan Barrios Jonathan B. Imran Audra T. Clark Luis Taveras Holly B. Cunningham Alana Christie Alexander L. Eastman Christian T. Minshall Stephen Luk Joseph P. Minei Herb A. Phelan Michael W. Cripps 《American journal of surgery》2019,217(1):90-97
Background
The Parkland Grading Scale for Cholecystitis (PGS) was developed as an intraoperative grading scale to stratify gallbladder (GB) disease severity during laparoscopic cholecystectomy (LC). We aimed to prospectively validate this scale as a measure of LC outcomes.Methods
Eleven surgeons took pictures of and prospectively graded the initial view of 317?GBs using PGS while performing LC (LIVE) between 9/2016 and 3/2017. Three independent surgeon raters retrospectively graded these saved GB images (STORED). The Intraclass Correlation Coefficient (ICC) statistic assessed rater reliability. Fisher's Exact, Jonckheere-Terpstra, or ANOVA tested association between peri-operative data and gallbladder grade.Results
ICC between LIVE and STORED PGS grades demonstrated excellent reliability (ICC?=?0.8210). Diagnosis of acute cholecystitis, difficulty of surgery, incidence of partial and open cholecystectomy rates, pre-op WBC, length of operation, and bile leak rates all significantly increased with increasing grade.Conclusions
PGS is a highly reliable, simple, operative based scale that can accurately predict outcomes after LC.Table of contents summary
The Parkland Grading Scale for Cholecystitis was found to be a reliable and accurate predictor of laparoscopic cholecystectomy outcomes. Diagnosis of acute cholecystitis, surgical difficulty, incidence of partial and open cholecystectomy rates, pre-op WBC, operation length, and bile leak rates all significantly increased with increasing grade. 相似文献6.
Archie L. Overmann DesRaj M. Clark Panagiotis Tsagkozis Rikard Wedin Jonathan A. Forsberg 《Journal of orthopaedic research》2020,38(10):2149-2156
Treatment decisions in patients with metastatic bone disease rely on accurate survival estimation. We developed the original PATHFx models using expensive, proprietary software and now seek to provide a more cost-effective solution. Using open-source machine learning software to create PATHFx version 2.0, we asked whether PATHFx 2.0 could be created using open-source methods and externally validated in two unique patient populations. The training set of a well-characterized, database records of 189 patients and the bnlearn package within R Version 3.5.1 (R Foundation for Statistical Computing), was used to establish a series of Bayesian belief network models designed to predict survival at 1, 3, 6, 12, 18, and 24 months. Each was externally validated in both a Scandinavian (n = 815 patients) and a Japanese (n = 261 patients) data set. Brier scores and receiver operating characteristic curves to assessed discriminatory ability. Decision curve analysis (DCA) evaluated whether models should be used clinically. DCA showed that the model should be used clinically at all time points in the Scandinavian data set. For the 1-month time point, DCA of the Japanese data set suggested to expect better outcomes assuming all patients will survive greater than 1 month. Brier scores for each curve demonstrate that the models are accurate at each time point. Statement of Clinical Significance: we successfully transitioned to PATHFx 2.0 using open-source software and externally validated it in two unique patient populations, which can be used as a cost-effective option to guide surgical decisions in patients with metastatic bone disease. 相似文献
7.
Joyce Black Michael Clark Carol Dealey Christopher T Brindle Paulo Alves Nick Santamaria Evan Call 《International wound journal》2015,12(4):484-488
The formulation of recommendations on the use of wound dressings in pressure ulcer prevention was undertaken by a group of experts in pressure ulcer prevention and treatment from Australia, Portugal, UK and USA. After review of literature, they concluded that there is adequate evidence to recommend the use of five‐layer silicone bordered dressings (Mepilex Border Sacrum® and 3 layer Mepilex Heel® dressings by Mölnlycke Health Care, Gothenburg, Sweden) for pressure ulcer prevention in the sacrum, buttocks and heels in high‐risk patients, those in Emergency Department (ED), intensive care unit (ICU) and operating room (OR). Literature on which this recommendation is based includes one prospective randomised control trial, three cohort studies and two case series. Recommendations for dressing use in patients at high risk for pressure injury and shear injury were also provided. 相似文献
8.
9.
Murat Yücel Erin Oldenhof Serge H. Ahmed David Belin Joel Billieux Henrietta Bowden‐Jones Adrian Carter Samuel R. Chamberlain Luke Clark Jason Connor Mark Daglish Geert Dom Pinhas Dannon Theodora Duka Maria Jose Fernandez‐Serrano Matt Field Ingmar Franken Rita Z. Goldstein Raul Gonzalez Anna E. Goudriaan Jon E. Grant Matthew J. Gullo Robert Hester David C. Hodgins Bernard Le Foll Rico S. C. Lee Anne Lingford‐Hughes Valentina Lorenzetti Scott J. Moeller Marcus R. Munaf Brian Odlaug Marc N. Potenza Rebecca Segrave Zsuzsika Sjoerds Nadia Solowij Wim van den Brink Ruth J. van Holst Valerie Voon Reinout Wiers Leonardo F. Fontenelle Antonio Verdejo‐Garcia 《Addiction (Abingdon, England)》2019,114(6):1095-1109
10.
Ali R. Cohen Thomas J.E. Clark Lynette M. Renner Pamela C. Carter Erin M. Shriver 《Canadian journal of ophthalmology. Journal canadien d'ophtalmologie》2019,54(3):355-358
ObjectiveDetermine the prevalence of intimate partner violence (IPV) as a mechanism of traumatic ocular injury in women, typical injury patterns, and the clinical course of affected patients. Encourage IPV screening and safety assessment in patients presenting with characteristic ocular trauma.MethodsMedical records of 211 female patients with traumatic ocular injuries evaluated at the University of Iowa Hospitals and Clinics between January 1995 and January 2015 were reviewed to determine the rate of IPV as a mechanism of ocular trauma. Twenty-one patients were excluded due to no documented trauma.ResultsLeading causes of traumatic ocular injuries in the 190 female patients included were accidental trauma with an inanimate object (n = 70/190, 36.8%), falls (n = 52/190, 27.4%), motor vehicle collisions (n = 21/190, 11.1%), and assault (n = 16/190, 8.4%). In 2.1% of cases (n = 4/190), no mechanism of traumatic injury was documented. Assault was the fourth leading mechanism of injury accounting for 8.4% of cases (n = 16/190), with IPV accounting for more than one third of cases with a documented perpetrator (n = 5/13). No perpetrator was documented in 18.8% (n = 3/16). All 5 patients with IPV-related injuries sustained scleral laceration or rupture; 4 out of 5 patients had no light perception vision and ultimately required enucleation.ConclusionIPV is an important mechanism of traumatic ocular injury. IPV-associated injuries tend to be severe in nature, as demonstrated by the high rate of globe laceration or rupture and subsequent enucleation in the study population. By appropriate screening and referral, ophthalmologists have an opportunity to redirect a potentially devastating course. 相似文献