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Andrs R. Prez‐Riera Raimundo Barbosa‐Barros Rodrigo Daminello‐Raimundo Luiz Carlos de Abreu Kjell Nikus 《Annals of noninvasive electrocardiology》2019,24(2)
Down syndrome occurs more frequently in the offsprings of older pregnant women and may be associated with atrioventricular septal defect. This refers to a broad spectrum of malformations characterized by a deficiency of the atrioventricular septum and abnormalities of the atrioventricular valves caused by an abnormal fusion of the superior and inferior endocardial cushions with the midportion of the atrial septum and the muscular portion of the ventricular septum. 相似文献
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Pereira Davisson Alves Mendes Pedro Gomes Junqueira de Souza Santos Samara de Rezende Barbosa Gabriella Lopes Pessoa Roberto Sales e de Oliveira Guilherme José Pimentel Lopes 《Lasers in medical science》2022,37(5):2479-2487
Lasers in Medical Science - The aim of this study was to evaluate the effect of photobiomodulation therapy (PBMT) with the association of red and infra-red laser therapy in the healing of the... 相似文献
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Fiene Marie Kuijper Uma V. Mahajan Seul Ku Daniel A.N. Barbosa Sheila M. Alessi Sherman C. Stein Kyle M. Kampman Brandon S. Bentzley Casey H. Halpern 《Neuromodulation》2022,25(2):253-262
ObjectivesCocaine is the second most frequently used illicit drug worldwide (after cannabis), and cocaine use disorder (CUD)-related deaths increased globally by 80% from 1990 to 2013. There is yet to be a regulatory-approved treatment. Emerging preclinical evidence indicates that deep brain stimulation (DBS) of the nucleus accumbens may be a therapeutic option. Prior to expanding the costly investigation of DBS for treatment of CUD, it is important to ensure societal cost-effectiveness.AimsWe conducted a threshold and cost-effectiveness analysis to determine the success rate at which DBS would be equivalent to contingency management (CM), recently identified as the most efficacious therapy for treatments of CUDs.Materials and MethodsQuality of life, efficacy, and safety parameters for CM were obtained from previous literature. Costs were calculated from a societal perspective. Our model predicted the utility benefit based on quality-adjusted life-years (QALYs) and incremental-cost-effectiveness ratio resulting from two treatments on a one-, two-, and five-year timeline.ResultsOn a one-year timeline, DBS would need to impart a success rate (ie, cocaine free) of 70% for it to yield the same utility benefit (0.492 QALYs per year) as CM. At no success rate would DBS be more cost-effective (incremental-cost-effectiveness ratio <$50,000) than CM during the first year. Nevertheless, as DBS costs are front loaded, DBS would need to achieve success rates of 74% and 51% for its cost-effectiveness to exceed that of CM over a two- and five-year period, respectively.ConclusionsWe find DBS would not be cost-effective in the short term (one year) but may be cost-effective in longer timelines. Since DBS holds promise to potentially be a cost-effective treatment for CUDs, future randomized controlled trials should be performed to assess its efficacy. 相似文献
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Camila Padilha Barbosa Rosalie Barreto Belian Cláudia Marina Tavares de Araújo 《Jornal de pediatria》2021,97(1):80-87
ObjectiveTo present, the process of development and evaluation of an educational software on the Child Health Handbook proposed for the continuing education of primary care nurses and physicians.MethodsQuantitative study of methodological development. For software development, the following steps were followed: definition of objectives; determination of the target audience; choice of pedagogical and theoretical reference for content; content selection and structuring; software development and evaluation by experts (five nurses and four physicians). All responded to an instrument that included four domains: pedagogical; content; functionality; system presentation and usability. The evaluation criteria were arranged on a Likert-type scale. The percentage of agreement and Content Validity Index were used for the quantitative analysis of the degree of agreement, considering a Content Validity Index cutoff point equal to 0.80.ResultsThe overall agreement index, calculated by the arithmetic mean of the Contents Validity Index of the evaluated domains, was 0.96, with scores ranging from 0.90 to 1.00. The average percentage of agreement of the experts per domain was 92.86%, with lower agreement in the content (80.95%), presentation, and usability (90.48%) domains. 100% of percentage of agreement was observed in the pedagogical and functionality domains among the evaluated specialists.ConclusionThe percentage of agreement, Content Validity Index and overall agreement index of the Child Health Handbook educational software in the context of primary care disclosed the software adequacy as an educational resource for continuing education of primary care nurses and physicians. Considering the assessed dimensions, it can also be used by other health professionals and undergraduate students. 相似文献
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Chaves Aline Lauda Freitas Silva Ana Gabriela Maia Flávia Medeiros Lopes Gabriela Francine Martins de Paulo Luiz Fernando Barbosa Muniz Luciana Vieira dos Santos Hélio Batista Soares João Marcos Arantes Souza Alexandre Andrade de Oliveira Barbosa Leandro Augusto Loyola Adriano Mota Murta Eddie Fernando Candido Michelin Márcia Antoniaze de Azambuja Ribeiro Rosy Iara Maciel 《Clinical oral investigations》2019,23(4):1913-1919
Clinical Oral Investigations - The aim of this study was to evaluate the immunohistochemical expressions of PD1, CD4+, and CD8+ in premalignant lesions (OPML) that were transformed into oral... 相似文献
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Menezes Juliana Dreyer Pereira Rodrigo dos Santos Santos Anderson Maikon de Souza de Siqueira Natália Barbosa Boos-Lima Fernanda Brasil Daura Jorge Hochuli-Vieira Eduardo 《Oral and maxillofacial surgery》2021,25(4):541-547
Oral and Maxillofacial Surgery - This study aimed to compare the three-dimensional volumetric changes of human maxillary sinuses after reconstruction using 5 different bone grafts. Patients... 相似文献
10.
Mariane C. F. Barbosa Daniela C. Lima Caio L. B. Reis Ana L. M. Reis Darlan Rigo Raquel A. B. Segato Carmen L. M. Storrer Erika C. Küchler Daniela S. B. de Oliveira 《International journal of paediatric dentistry / the British Paedodontic Society [and] the International Association of Dentistry for Children》2020,30(5):642-649