全文获取类型
收费全文 | 2611篇 |
免费 | 178篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 32篇 |
儿科学 | 165篇 |
妇产科学 | 37篇 |
基础医学 | 285篇 |
口腔科学 | 58篇 |
临床医学 | 204篇 |
内科学 | 423篇 |
皮肤病学 | 43篇 |
神经病学 | 284篇 |
特种医学 | 145篇 |
外科学 | 363篇 |
综合类 | 107篇 |
一般理论 | 3篇 |
预防医学 | 188篇 |
眼科学 | 60篇 |
药学 | 188篇 |
中国医学 | 4篇 |
肿瘤学 | 210篇 |
出版年
2023年 | 26篇 |
2022年 | 20篇 |
2021年 | 84篇 |
2020年 | 39篇 |
2019年 | 71篇 |
2018年 | 94篇 |
2017年 | 67篇 |
2016年 | 85篇 |
2015年 | 87篇 |
2014年 | 126篇 |
2013年 | 130篇 |
2012年 | 174篇 |
2011年 | 191篇 |
2010年 | 122篇 |
2009年 | 96篇 |
2008年 | 168篇 |
2007年 | 169篇 |
2006年 | 123篇 |
2005年 | 145篇 |
2004年 | 128篇 |
2003年 | 104篇 |
2002年 | 81篇 |
2001年 | 55篇 |
2000年 | 63篇 |
1999年 | 45篇 |
1998年 | 17篇 |
1997年 | 15篇 |
1996年 | 15篇 |
1995年 | 13篇 |
1994年 | 5篇 |
1993年 | 10篇 |
1992年 | 19篇 |
1991年 | 28篇 |
1990年 | 25篇 |
1989年 | 21篇 |
1988年 | 16篇 |
1987年 | 18篇 |
1986年 | 20篇 |
1985年 | 9篇 |
1984年 | 11篇 |
1983年 | 9篇 |
1982年 | 4篇 |
1981年 | 6篇 |
1980年 | 6篇 |
1979年 | 4篇 |
1978年 | 5篇 |
1976年 | 3篇 |
1975年 | 3篇 |
1967年 | 4篇 |
1966年 | 3篇 |
排序方式: 共有2799条查询结果,搜索用时 78 毫秒
1.
2.
Goyal Riya Rana Radhamohan Bhatia Hitesh Kaushik Jaya Shankar 《Indian journal of pediatrics》2020,87(3):225-225
Indian Journal of Pediatrics - 相似文献
3.
Shwetank Mishra Shankar Prasad Hazra Vinod Priyadarshi Hemant Goel Dilip Kumar Pal 《The Indian journal of surgery》2015,77(1):59-61
Renal cell carcinoma (RCC) may metastasize to almost any organ, but metastasis to the small bowel is very rare. Factors responsible for a resistant behavior of small bowel wall are still not clear. Small bowel metastasis from RCC may cause obstruction, bleeding, and perforation. RCC metastasis to the small bowel presenting as intussusception is extremely rare. Only 20 cases of small bowel intussusceptions caused by metastatic RCC have been reported worldwide. Here, we are reporting this rare case of RCC with simultaneous solitary metastasis in jejunum which presented as intussusceptions and which was treated with simultaneous radical nephrectomy, jejunal resection, and anastomosis. 相似文献
4.
Christine Mlzer Sucharita P. Shankar Vlad Masalski May Griffith Lucia Kuffov John V. Forrester 《Journal of tissue engineering and regenerative medicine》2019,13(9):1507-1517
We showed previously that 1‐ethyl‐3‐(3‐dimethylamino‐propyl)‐carbodiimide hydrochloride (EDC) cross‐linked recombinant human collagen III hydrogels promoted stable regeneration of the human cornea (continued nerve and stromal cell repopulation) for over 4 years. However, as EDC cross linking kinetics were difficult to control, we additionally tested a sterically bulky carbodiimide. Here, we compared the effects of two carbodiimide cross linkers—bulky, aromatic N‐cyclohexyl‐N0‐(2‐morpholinoethyl)‐carbodiimide (CMC), and nonbulky EDC—in a mouse corneal graft model. Murine corneas undergoing full‐thickness implantation with these gels became opaque due to dense retro‐corneal membranes (RCM). Corneal epithelial cytokeratin 12 and alpha smooth muscle actin indicative of functional tissue regeneration and wound contraction were observed in RCM surrounding both hydrogel types. However, quantitatively different levels of infiltrating CD11c+ dendritic cells (DC) were found, suggesting a hydrogel‐specific innate immune response. More DC infiltrated the stroma surrounding EDC‐N‐hydroxysuccinimide (NHS) hydrogels concurrently with higher fibrosis‐associated tenascin c expression. The opposite was true for CMC‐NHS gels that had previously been shown to be more tolerising to DC. In vitro studies showed that DC cultured with transforming growth factor β1 (TGF‐β1) induced fibroblasts to secrete more tenascin c than those cultured with lipopolysaccharide and this effect was blocked by TGF‐β1 neutralisation. Furthermore, tenascin c staining was found in 40‐ to 50μm long membrane nanotubes formed in fibroblast/DC cocultures. We suggest that TGF‐β1 alternatively activated (tolerising) DC regulate fibroblast‐mediated tenascin c secretion, possibly via local production of TGF‐β1 in early wound contraction, and that this is indirectly modulated by different hydrogel chemistries. 相似文献
5.
Niharika Saw Joshua C. Vacanti Xiaoxia Liu Monica SaRego Hugh Flanagan Bhavani Shankar Kodali 《Journal of investigative surgery》2015,28(2):95-102
Purpose: On time start of the first surgical case improves operating room (OR) utilization, physician, and patient satisfaction and decreases delays in subsequent cases. The goal of our study was to evaluate the effect of a multidisciplinary initiative to improve first patient in the room (FPIR) and first case on time start (FCOTS) metrics in a tertiary care setting. Materials and Methods: A multidisciplinary committee focused on first case start data collection. Reasons for both anesthesia and surgical delays were analyzed. Improvement efforts focused on the timely completion of surgical consent, a requirement of a surgical, anesthesia, and nurse team member presence at the patient's bedside by specific time, and parallel processing in the OR. Results: Over 65,100 OR cases were analyzed between 2007 and 2014. There was a statistically significant improvement in FPIR (82.80% versus 69.60%, p < .0001) and FCOTS (66.60% versus 55.90%, p < .0001). Surgical consent completion rate increased from 35% baseline to 68%–100%, depending on the surgical subspecialty. Improvements appeared sustainable several years following process implementation for both FPIR (84.60% versus 69.60%, p < .0001) and FCOTS (67.60% versus 55.90%, p < .0001). Conclusions: Our study demonstrates a successful targeted, multidisciplinary initiative to improve first case surgical starts in an academic setting. Our approach was organizational rather than punitive or rewarding on an individual basis. Strategies included establishing concrete, time-specific goals and posting them visibly, empowering individuals to fulfill them, and ensuring no compromise in patient safety. In the complex environment of academic medicine including research protocols and teaching in the ORs, our organizational approach proved sustainable over several years. 相似文献
6.
Mohd. Aamir Kundan Mittal Jaya Shankar Kaushik Haripal Kashyap Gurpreet Kaur 《Indian journal of pediatrics》2014,81(11):1167-1170
Objective
To determine the sociodemographic and clinical factors leading to stress among parents whose children are admitted in pediatric intensive care unit (PICU).Methods
A prospective observational study was conducted in PICU of a tertiary care hospital of north India. Parents of children admitted to PICU for at least 48 h duration were eligible for participation. At the end of 48 h, parental stress was assessed using parental stress scale (PSS:PICU) questionnaire which was administered to the parents. Baseline demographic and clinical parameters of children admitted to PICU were recorded. The parental stress was compared with demographic and clinical characteristics of children using appropriate statistical methods.Results
A total of 49 parents were finally eligible for participation. Mean (SD) parental stress scores was highest in domains of procedures [1.52 (0.66)] and behavior and emotional [1.32 (0.42)] subscales. Mean (SD) total parental stress score among intubated children [1.31 (0.25)] was significantly more than among non intubated children [0.97 (0.26)] (p?0.001). However, parental stress score were comparable in terms of gender (p?=?0.15) and socioeconomic status (p?=?0.32). On subscale analysis, it was found that professional communication is a significant stressor in age groups 0–12 mo [0.61(0.41)] (p?=?0.02). It was observed that parents of intubated children were significantly stressed by the physical appearance of their children (p?0.001), procedures performed on them (p?=?0.008) and impairment in parental role (p?=?0.002). Total parental stress score had a positive correlation with PRISM score (r?=?0.308).Conclusions
Indian parents are stressed maximally with environment of PICU. Factor leading to parental stress was intubation status of the child and was not affected by gender or socio demographic profile of the parents. 相似文献7.
8.
In fixed prosthodontic procedures, when it has been determined that restoration of all or most of the posterior teeth is necessary, the use of the Broderick occlusal plane analyzer provides an easy and practical method to determine an occlusal plane that will fulfill esthetic and functional occlusion requirements. However, several manufacturers of semiadjustable articulators offer no such occlusal plane analyzers for use with these instruments. This article demonstrates the use of a custom-made Broderick occlusal plane analyzer with a semiadjustable articulator to determine the correct curve of Spee for the occlusal plane. 相似文献
9.
10.
Ranjit Kumar Sahu Prakash Chandra Kal Pawan Kumar Dixit Sourabh Shankar Chakraborty Suresh K Deepti Katrolia 《中华创伤杂志(英文版)》2020,23(5):307-310
Purpose: Fingertip injuries are common in industrial production activities as well as in domestic work. Loss of pulp hampers daily life activities. Functional and aesthetic aspects are important in fingertip reconstruction. The bone is usually exposed along with soft tissue loss. Therefore to reconstruct the pulp flap with adequate bulk is required.
Methods: We reported a case series of 12 patients with the injury over the volar aspect of distal phalanx of the index or middle finger. In all cases, laterally based thenar flap was chosen. The flap donor site was closed primarily in most of cases, while 4 patients required skin graft. The flap was detached between 2-3 weeks. Functional assessment was done using static and dynamic 2-point discrimination and range of motion at each joint. The aesthetic outcome was assessed through questionnaire. The results were analyzed using the unpaired t-test (SPSS version 21).
Results: Partial necrosis occurred in 2 cases while rest of flaps survived successfully. Static 2-point discrimination ranged from 6e10 mm, mean 8.6 mm; and dynamic 2-point discrimination ranged from 8-10 mm, mean 8.9 mm. The mean satisfaction score was (4.0 ± 0.55).
Conclusion: Thenar flap is a good choice for reconstruction of the finger pulp as it provides the bulk with good functional and aesthetic outcome. 相似文献