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1.
M Lattere U Rosati M Chiossi F Facco M Magnani A Calvi S Renna S Bonassi 《Minerva pediatrica》1992,44(9):407-412
A perspective study was carried out at the Emergency Department of the Gaslini Institute on a sample of the children admitted from May to September 1990. The study aimed to describe types and modalities of admission. "G. Gaslini" Institute is a multidisciplinary children's hospital: 45% of patients admitted in the hospital come from the southern regions of Italy, while the admission at the Emergency Department were local in 82%. Among all children considered, 2080 (71.9% were admitted on request of their parents, who did not ask previously any physician; of those cases, 356 (17%) were hospitalized, 474 (25%) were either examined by specialist or treated and then discharged. In the remaining cases, no intervention was necessary. As a consequence, 58% of children were admitted without any clinically plausible reason. Parents' anxiety clearly played an important role in most cases. 840 children were addressed to the Emergency Department by a physician, 652 (22.3%) by the doctor in charge, 213 (32.7%) of which were sent back home by the doctor on duty, who did not think it necessary any treatment. Of the 120 (4.1%) children sent by different Emergency Departments, 95 (79.1%) were hospitalized. The reason why physicians addressed quite a large number of children to the Emergency Department, when they didn't need any intervention remain nucleo. Their diagnosis, in fact, agreed with those of the doctor on duty in 83% of cases. In conclusion, it is difficult to imagine a diagnostic or therapeutic problem which needs specific structures. Cooperative programs with physicians working in our region will be carried out in order to control, where possible, admission to Emergency Departments. 相似文献
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M Lattere F Facco M Chiossi L De Santis A Galletti M Magnani M Raspino S Renna A Tarateta U Rosati 《Minerva pediatrica》1992,44(6):279-284
The authors reviewed records of admission at the Fist Ais-Emergency Service of "G. Gaslini" Children's Hospital, data referring both to in and outpatients. First of all we took into account epidemiological data analysing occurrence and types of diseases; at the same time a demographic study, which aimed to show a decrease in the child population in Genova, was performed. Secondly we compared these data with the real number of admitted patients: collected data showed that this service has been used excessively. 相似文献
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Fabio Salvatore Macaluso Marco Ventimiglia Walter Fries Anna Viola Aldo Sitibondo Maria Cappello Barbara Scrivo Anita Busacca Antonino Carlo Privitera Salvatore Camilleri Serena Garufi Roberto Di Mitri Filippo Mocciaro Nunzio Belluardo Emiliano Giangreco Carmelo Bertolami Sara Renna Rosalba Orlando Giulia Rizzuto Mario Cottone Ambrogio Orlando 《Journal of gastroenterology and hepatology》2021,36(1):105-111
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Anna Viola Daniela Pugliese Sara Renna Federica Furfaro Flavio Caprioli Renata D’Incà Fabrizio Bossa Stefano Mazza Giuseppe Costantino Massimo Claudio Fantini Gionata Fiorino Angela Alibrandi Ambrogio Orlando Alessandro Armuzzi Walter Fries 《Digestive and liver disease》2019,51(4):510-515
Background
Anti-TNF therapies infliximab (IFX), adalimumab (ADA), and golimumab (GOL) are approved for treating moderate to severe ulcerative colitis (UC). In UC, only the switch from IFX to ADA has been investigated, reaching no more than 10–43% remission rates at 12 months.Aim
Of the present study was to investigate disease outcome after a switch from subcutaneous (SC) agents to the intravenous (IV) agent (IFX).Methods
In this retrospective multicentre study, we analysed the charts of UC patients unresponsive/intolerant or with secondary loss of response (LOR) to ADA or GOL who were switched to IFX. We evaluated clinical response and remission together with adverse events at 3, 6, and 12 months follow-up.Results
Seventy-six patients were included; 38 patients started ADA and 38 started GOL for a mean therapy duration of 6?±?6 months. Indications for switch were adverse events in 3%, primary failure in 79%, and LOR in 18% of patients. Clinical remission was reached by 47%, 50%, and 77% of patients, respectively. Patients that switched for LOR did numerically, but not statistically, better than patients who switched for primary failure.Conclusions
Our data show a superior remission rate in SC to IV anti-TNF switch in UC compared to the IV to SC switch reported in literature. 相似文献7.
目的:了解该地区 RhD 阴性献血者表型分布,建立 RhD 阴性表型数据库。方法 RhD 初筛阴性的554份标本采用间接抗球蛋白试验确认。排除重复献血者后,剩余标本为366份,对其进行 Rh 血型表型分析。结果 RhD 阴性表型分布特征为ccdee(56.28%)> Ccdee (29.51%)> ccdEe (7.38%)> CcdEe (3.55%)> CCdee (3.01%)> ccdEE (0.27%),未检出 CcdEE 、CCdEe 、CCdEE 型。结论建立 RhD 阴性表型数据库,有利于为 RhD 阴性及含有 Rh 同种抗体的患者提供相匹配血液,满足其急救用血,且对科学管理 RhD 阴性血源和合理运用 RhD 阴性血液有重要意义,为该地区尤其蒙古族 RhD 阴性血型积累了资料。 相似文献
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Vegard Antun Francesco Renna Clarice Poon Ben Adcock Anders C. Hansen 《Proceedings of the National Academy of Sciences of the United States of America》2020,117(48):30088
Deep learning, due to its unprecedented success in tasks such as image classification, has emerged as a new tool in image reconstruction with potential to change the field. In this paper, we demonstrate a crucial phenomenon: Deep learning typically yields unstable methods for image reconstruction. The instabilities usually occur in several forms: 1) Certain tiny, almost undetectable perturbations, both in the image and sampling domain, may result in severe artefacts in the reconstruction; 2) a small structural change, for example, a tumor, may not be captured in the reconstructed image; and 3) (a counterintuitive type of instability) more samples may yield poorer performance. Our stability test with algorithms and easy-to-use software detects the instability phenomena. The test is aimed at researchers, to test their networks for instabilities, and for government agencies, such as the Food and Drug Administration (FDA), to secure safe use of deep learning methods. 相似文献
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