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J. Gaudelus R. Cohen B. Leboucher J.P. Stahl F. Denis P. Pujol L. Longfier A. Martinot 《Médecine et maladies infectieuses》2019,49(3):180-186
Objectives
Meningococcal C (MenC) vaccination was introduced in the French vaccination calendar in 2010 to reduce the incidence of invasive meningococcal C disease (IMD C), mainly through herd immunity. The Vaccinoscopie survey helps follow vaccination coverage rates (VCRs) of children.Methods
This annual survey is based on a self-administered online questionnaire. In 2017, 4500 mothers of children completed the questionnaire and reported all vaccinations recorded in their child's health record.Results
MenC vaccination was deemed indispensable or useful by 77% to 84% of mothers. The main barrier mentioned by mothers considering the vaccination useless/not very useful, was fear of adverse effects. VCR was estimated at 77% among 24-35-month-old infants, 79% among 6-year-old children, and 50% among 14-15-year-old adolescents. VCR strongly varied depending on the physician's advice for vaccination and on the type of follow-up. Six months after publication of the new French vaccine calendar in April 2017, with a MenC vaccine recommendation for all 5-month-old infants, 43% of infants had received a dose at 6 months of age.Conclusions
VCRs are insufficient to reach herd immunity. Between 2011 and 2017 more than 100 deaths could have been avoided in France if optimal VCRs had been achieved. Faced with this vaccine strategy failure, the new vaccine recommendation at 5 months of age seems well-accepted. This recommendation and the implementation of infant mandatory vaccination in 2018 should have a major impact on IMD C incidence in this age group. 相似文献6.
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Bazert C Boileau MJ de Brondeau F Dorignac D el Amrani-Darqué K Garnier E Perrier M Pujol A Rotenberg M Dorignac D 《L' Orthodontie fran?aise》2002,73(2):125-178
Complex dysmorphies, asymmetries can affect the various elements of the stomatognathic system: cranial base, maxilla, mandible, musculature and dental arches, in the three dimensions of space. Their etiopathogenesis, as well as their clinical forms, vary considerably. Dysembryopathies, growth disorders, TMJ damages, postural or functional disorders and dental anomalies can create, according to their severity and their moment of appearance, severe or minor facial asymmetries, or asymmetries of the arches. An exo- and endobuccal clinical examination endeavors to specify the localization and the severity of the damage, and to evaluate the importance of the possible alveolar compensations. Consolidated by additional examinations, it enables the clinician to differentiate the various forms of asymmetries. 相似文献
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E. Levine N. Beroul A. Cortey A. Damais Cepitelli H. Gouezec S. Pujol B. Wibaut B. Marti 《Transfusion Clinique et Biologique》2018,25(4):249-256