全文获取类型
收费全文 | 666篇 |
免费 | 54篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 13篇 |
儿科学 | 39篇 |
妇产科学 | 14篇 |
基础医学 | 111篇 |
口腔科学 | 35篇 |
临床医学 | 74篇 |
内科学 | 101篇 |
皮肤病学 | 17篇 |
神经病学 | 27篇 |
特种医学 | 31篇 |
外科学 | 67篇 |
综合类 | 36篇 |
预防医学 | 52篇 |
眼科学 | 6篇 |
药学 | 74篇 |
中国医学 | 1篇 |
肿瘤学 | 28篇 |
出版年
2021年 | 9篇 |
2020年 | 17篇 |
2019年 | 11篇 |
2018年 | 16篇 |
2017年 | 8篇 |
2016年 | 5篇 |
2015年 | 19篇 |
2014年 | 29篇 |
2013年 | 26篇 |
2012年 | 28篇 |
2011年 | 36篇 |
2010年 | 26篇 |
2009年 | 21篇 |
2008年 | 26篇 |
2007年 | 36篇 |
2006年 | 17篇 |
2005年 | 20篇 |
2004年 | 23篇 |
2003年 | 19篇 |
2002年 | 16篇 |
2001年 | 6篇 |
2000年 | 20篇 |
1999年 | 15篇 |
1998年 | 19篇 |
1997年 | 11篇 |
1996年 | 16篇 |
1995年 | 11篇 |
1994年 | 18篇 |
1993年 | 9篇 |
1992年 | 11篇 |
1991年 | 10篇 |
1990年 | 7篇 |
1989年 | 10篇 |
1988年 | 15篇 |
1987年 | 10篇 |
1986年 | 13篇 |
1985年 | 13篇 |
1984年 | 8篇 |
1983年 | 10篇 |
1982年 | 6篇 |
1981年 | 7篇 |
1980年 | 4篇 |
1976年 | 4篇 |
1975年 | 4篇 |
1974年 | 8篇 |
1973年 | 10篇 |
1970年 | 5篇 |
1968年 | 3篇 |
1967年 | 3篇 |
1966年 | 4篇 |
排序方式: 共有726条查询结果,搜索用时 78 毫秒
1.
2.
3.
John N. Trantalis Stephen Sohmer Kristie D. More Atiba A. Nelson Ben Wong Corinne H. Dyke Gail M. Thornton Richard S. Boorman Ian K.Y. Lo 《International journal of shoulder surgery》2015,9(3):74-80
Aims:The aim was to evaluate the clinical and anatomic outcome of arthroscopic repair of type II SLAP lesions.Results:At a mean follow-up of 54-month, the mean American Shoulder and Elbow Surgeons Shoulder Index (ASES) scores improved from 52.1 preoperatively to 86.1 postoperatively (P < 0.0001) and the Simple Shoulder Test (SST) scores from 7.7 to 10.6 (P < 0.0002). Twenty-two out of the 25 patients (88%) stated that they would have surgery again. Of the 21 patients who had postoperative magnetic resonance imaging arthrographys (MRAs), 9 patients (43%) demonstrated dye tracking between the labrum bone interface suggestive of a recurrent tear and 12 patients (57%) had a completely intact repair. There was no significant difference in ASES, SST, and patient satisfaction scores in patients with recurrent or intact repairs.Conclusions:Arthroscopic repair of type II SLAP lesions demonstrated improvements in clinical outcomes. However, MRA imaging demonstrated 43% of patients with recurrent tears. MRA results do not necessarily correlate with clinical outcome. 相似文献
4.
The purpose of this investigation was to study the intra-oral rehardening of acid-softened enamel and fluoride uptake from SnF2 gel. Bovine enamel slabs were softened with 0.1 mol/L lactate buffer at pH 4.0 for 14 hrs and then mounted in a mandibular removable Hawley appliance. Control slabs were worn for 96 hrs by seven adult males whose teeth were brushed daily with a fluoride-free dentifrice. Test slabs were exposed once/day to 0.4% SnF2 gel. The gel was swabbed onto the slabs for one minute before being replaced in the mouth unrinsed. The natural dentition was brushed 4 X /day with a fluoride-free dentifrice. Microhardness testing was performed after intra-oral exposure (IOE) and after acid-resistance-testing (ART) following immersion in 0.01 mol/L lactate buffer for 24 hrs at pH of 4.0. Fluoride uptake was measured on separate controls, test slabs, and test slabs after ART, with 0.5 mol/L HClO4 etches of from 15 to 60 sec. The F content was measured with a F-ion-specific electrode and the phosphate content by spectrophotometry. Following IOE, microhardness recovery was 35.6% for control and 37.9% for test slabs, and control slabs retained 1.4% resistance to acid, as compared with 18.6% for the test slabs. The F content of control slabs was significantly less than that of SnF2-treated slabs from 5 to 60 micron in depth, and the F content of SnF2-treated slabs after ART was significantly less at depths of from 5 to 35 micron than that of SnF2-treated slabs not exposed to ART. Both control and SnF2 enamel slabs demonstrated rehardening after IOE, but only SnF2-treated enamel retained a significant fraction of that rehardening after ART. 相似文献
5.
Placebo controls play a critical role in the evaluation of any pharmacotherapy. This review surveys the placebo arm in 12 randomized controlled trials (RCTs) investigating burning mouth syndrome (BMS) and documents a positive placebo response in 6 of them. On average, treatment with placebos produced a response that was 72% as large as the response to active drugs. The lack of homogeneity in the use of placebos adds to the difficulty in comparing results and aggregating data. Future RCTs investigating BMS would benefit from larger sample sizes, adequate follow‐up periods, and use of a standard placebo. 相似文献
6.
Kandasamy K Prawez S Choudhury S More AS Ahanger AA Singh TU Parida S Mishra SK 《Shock (Augusta, Ga.)》2011,36(1):76-82
Hyporeactivity to vasoconstrictors is one of the clinical manifestations of sepsis in man and experimental animals. The objective of the investigation was to examine whether atorvastatin can prevent hyporeactivity to norepinephrine (NE) in mouse aorta in sepsis, and if so, what are the mechanisms involved. Sepsis in mice was induced by cecal ligation and puncture. The aorta was harvested for tension experiment, nitric oxide (NO) and cyclic guanosine monophosphate measurements, and inducible NO synthase (iNOS) and α(1D)-adrenoceptor mRNA expression studies. In comparison with sham-operated controls, sepsis significantly decreased the contractile response to NE in the mouse aorta. Pretreatment with atorvastatin of septic animals completely restored NE-induced contractions to levels similar to those of sham-operated controls and significantly increased survival time and mean arterial pressure. Atorvastatin also attenuated iNOS-induced overproduction of NO, as well as iNOS mRNA expression. Accordingly, hyporeactivity to NE was not evident in tissues pretreated with selective iNOS inhibitor 1400W in sepsis. Although basal cyclic guanosine monophosphate accumulation in the aorta was reduced in sepsis, pretreatment of the tissues with soluble guanylyl cyclase inhibitor 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one (ODQ) partially restored the reactivity to NE. Interestingly, hyporeactivity to NE in sepsis was associated with a decreased α(1D)-adrenoceptor mRNA expression in the mouse aorta. Atorvastatin pretreatment, however, prevented the decrease in α(1D)-adrenoceptor mRNA expression in septic animals. In conclusion, atorvastatin seems to prevent hyporeactivity to vasoconstrictor NE in the aorta from septic mice through attenuation of overproduction of NO as well as improved α(1D)-adrenoceptor mRNA expression. The findings of the present study may explain the beneficial effects of atorvastatin on improved hemodynamic functions in sepsis. 相似文献
7.
Anti-thrombotic therapy for non-rheumatic atrial fibrillation 总被引:1,自引:0,他引:1
Recent randomized trials of antithrombotic therapy in non-rheumatic atrial
fibrillation have helped to clarify the benefits of warfarin and aspirin.
Low-risk patients (normotensives aged <60 with normal left
ventricular function) have a small risk of thromboembolic events and are
unlikely to benefit significantly from anticoagulants, but may benefit from
aspirin with little increase in risk of bleeding. High-risk patients
(>75 years, impaired left ventricular function, previous
thromboembolism and/or associated conditions such as hypertension and
diabetes mellitus) have an increased risk of thromboembolism, and benefit
from long-term anticoagulant therapy to a greater degree than with aspirin,
although at a risk of increased bleeding complications.
相似文献
8.
9.
A Sama FRCS JCE Meikle BA NS Jones FRCS 《International journal of clinical practice》1995,49(2):79-82
SUMMARY Dizziness is a common symptom in patients presenting to an otorhinolaryngologist. Hyperventilation accounts for up to 5% of cases with dizziness and is a contributory factor in a further 20% of cases. Six cases of dizziness due to hyperventilation are presented to illustrate the authors' simple management policy. A high index of suspicion in the absence of an organic cause of dizziness and a simple provocation test will identify these cases. Management is aimed at demonstrating resting hypocapnia, investigations to exclude organic causes of hyperventilation and rehabilitation in collaboration with a clinical psychologist ensures the appropriate treatment for the dizziness and can avoid the development of chronic somatisation behaviours. 相似文献