全文获取类型
收费全文 | 6892篇 |
免费 | 416篇 |
国内免费 | 12篇 |
专业分类
耳鼻咽喉 | 88篇 |
儿科学 | 272篇 |
妇产科学 | 157篇 |
基础医学 | 856篇 |
口腔科学 | 61篇 |
临床医学 | 1222篇 |
内科学 | 1268篇 |
皮肤病学 | 70篇 |
神经病学 | 682篇 |
特种医学 | 92篇 |
外科学 | 561篇 |
综合类 | 87篇 |
一般理论 | 6篇 |
预防医学 | 895篇 |
眼科学 | 106篇 |
药学 | 380篇 |
中国医学 | 11篇 |
肿瘤学 | 506篇 |
出版年
2023年 | 23篇 |
2022年 | 15篇 |
2021年 | 71篇 |
2020年 | 77篇 |
2019年 | 105篇 |
2018年 | 126篇 |
2017年 | 115篇 |
2016年 | 107篇 |
2015年 | 135篇 |
2014年 | 199篇 |
2013年 | 325篇 |
2012年 | 456篇 |
2011年 | 478篇 |
2010年 | 293篇 |
2009年 | 254篇 |
2008年 | 467篇 |
2007年 | 505篇 |
2006年 | 517篇 |
2005年 | 517篇 |
2004年 | 464篇 |
2003年 | 526篇 |
2002年 | 494篇 |
2001年 | 54篇 |
2000年 | 58篇 |
1999年 | 59篇 |
1998年 | 86篇 |
1997年 | 62篇 |
1996年 | 52篇 |
1995年 | 52篇 |
1994年 | 50篇 |
1993年 | 53篇 |
1992年 | 32篇 |
1991年 | 42篇 |
1990年 | 28篇 |
1989年 | 33篇 |
1988年 | 33篇 |
1987年 | 30篇 |
1986年 | 19篇 |
1985年 | 24篇 |
1984年 | 32篇 |
1983年 | 33篇 |
1982年 | 24篇 |
1981年 | 31篇 |
1980年 | 26篇 |
1979年 | 15篇 |
1978年 | 18篇 |
1977年 | 14篇 |
1976年 | 20篇 |
1974年 | 8篇 |
1973年 | 12篇 |
排序方式: 共有7320条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
Hermann Einsele MD Hossein Borghaei DO Robert Z. Orlowski MD Marion Subklewe MD Gail J. Roboz MD Gerhard Zugmaier MD Peter Kufer MD Karim Iskander MD Hagop M. Kantarjian MD 《Cancer》2020,126(14):3192-3201
Immuno-oncology therapies engage the immune system to treat cancer. BiTE (bispecific T-cell engager) technology is a targeted immuno-oncology platform that connects patients' own T cells to malignant cells. The modular nature of BiTE technology facilitates the generation of molecules against tumor-specific antigens, allowing off-the-shelf immuno-oncotherapy. Blinatumomab was the first approved canonical BiTE molecule and targets CD19 surface antigens on B cells, making blinatumomab largely independent of genetic alterations or intracellular escape mechanisms. Additional BiTE molecules in development target other hematologic malignancies (eg, multiple myeloma, acute myeloid leukemia, and B-cell non-Hodgkin lymphoma) and solid tumors (eg, prostate cancer, glioblastoma, gastric cancer, and small-cell lung cancer). BiTE molecules with an extended half-life relative to the canonical BiTE molecules are also being developed. Advances in immuno-oncology made with BiTE technology could substantially improve the treatment of hematologic and solid tumors and offer enhanced activity in combination with other treatments. 相似文献
6.
7.
Donna M. Wilson PHD Andrea Rodríguez-Prat PHD Gail Low PHD 《Social work in health care》2020,59(6):335-350
ABSTRACT Bereavement grief is typically very painful and often highly consequential. People who are working could be significantly impacted by the death of someone they care about. A qualitative study sought an understanding of the lived experience of bereavement on the mourner’s ability to work and their work-related experiences following the death of a loved one. Three themes emerged: (a) grief is universal but individually impactful, (b) accommodation is needed to assist the return to work and to regain work abilities, and (c) there are many impediments to working again. These themes highlight the potential for bereavement grief to substantially effect mourners and thus their work, careers, and the workplace. Older workers could be particularly disadvantaged because of workplace ageism. Societal and other changes appear to be needed for the health and wellbeing of mourning workers, and to address related work and bereavement issues. Bereavement grief is highly relevant to the social work profession, given its involvement in providing information, developing supportive services, and making referrals. 相似文献
8.
9.
10.
Bambi L. DeLaRosa Jeffrey S. Spence Nyaz Didehbani Gail D. Tillman Michael A. Motes Christina Bass Michael A. Kraut John Hart 《Human brain mapping》2020,41(1):218-229
Post‐traumatic stress disorder (PTSD) is a debilitating condition that may develop after experiencing a traumatic event. Combat exposure increases an individual's chance of developing PTSD, making veterans especially susceptible to the disorder. PTSD is characterized by dysregulated emotional networks, memory deficits, and a hyperattentive response to perceived threatening stimuli. Recently, there have been a number of imaging studies that show structural and functional abnormalities associated with PTSD; however, there have been few studies utilizing electroencephalography (EEG). The goal of this study was to characterize **EEG brain dynamics in individuals with PTSD, in order to better understand the neurophysiological underpinnings of some of the salient features of PTSD, such as threat‐processing bias. Veterans of Operation Enduring Freedom/Iraqi Freedom completed an implicit visual threat semantic memory recognition task with stimuli that varied on both category (animals, items, nature, and people) and feature (threatening and nonthreatening) membership, including trauma‐related stimuli. Combat veterans with PTSD had slower reaction times for the threatening stimuli relative to the combat veterans without PTSD (VETC). There were trauma‐specific effects in frontal regions, with theta band EEG power reductions for the threatening combat scenes in the PTSD patients compared to the VETC group. Additionally, a moderate negative correlation was observed between trauma‐specific frontal theta power and hyperarousal symptoms as measured by clinically administered PTSD scale. These findings complement and extend current models of cortico‐limbic dysfunction in PTSD. The moderate negative correlation between frontal theta power and hyperarousal endorsements suggests the utility of these measures as therapeutic markers of symptomatology in PTSD patients. 相似文献