全文获取类型
收费全文 | 2777篇 |
免费 | 164篇 |
国内免费 | 5篇 |
专业分类
耳鼻咽喉 | 50篇 |
儿科学 | 103篇 |
妇产科学 | 19篇 |
基础医学 | 341篇 |
口腔科学 | 48篇 |
临床医学 | 182篇 |
内科学 | 560篇 |
皮肤病学 | 65篇 |
神经病学 | 197篇 |
特种医学 | 93篇 |
外科学 | 388篇 |
综合类 | 16篇 |
预防医学 | 85篇 |
眼科学 | 187篇 |
药学 | 298篇 |
中国医学 | 9篇 |
肿瘤学 | 305篇 |
出版年
2023年 | 8篇 |
2022年 | 10篇 |
2021年 | 49篇 |
2020年 | 27篇 |
2019年 | 40篇 |
2018年 | 67篇 |
2017年 | 45篇 |
2016年 | 65篇 |
2015年 | 64篇 |
2014年 | 71篇 |
2013年 | 83篇 |
2012年 | 177篇 |
2011年 | 169篇 |
2010年 | 109篇 |
2009年 | 95篇 |
2008年 | 146篇 |
2007年 | 194篇 |
2006年 | 166篇 |
2005年 | 172篇 |
2004年 | 147篇 |
2003年 | 128篇 |
2002年 | 145篇 |
2001年 | 70篇 |
2000年 | 57篇 |
1999年 | 76篇 |
1998年 | 42篇 |
1997年 | 35篇 |
1996年 | 28篇 |
1995年 | 21篇 |
1994年 | 17篇 |
1993年 | 10篇 |
1992年 | 34篇 |
1991年 | 44篇 |
1990年 | 35篇 |
1989年 | 36篇 |
1988年 | 23篇 |
1987年 | 27篇 |
1986年 | 22篇 |
1985年 | 23篇 |
1984年 | 19篇 |
1983年 | 10篇 |
1981年 | 8篇 |
1980年 | 11篇 |
1979年 | 16篇 |
1978年 | 8篇 |
1971年 | 7篇 |
1970年 | 10篇 |
1969年 | 9篇 |
1968年 | 9篇 |
1967年 | 10篇 |
排序方式: 共有2946条查询结果,搜索用时 15 毫秒
1.
2.
3.
L Sumitra Hada Nobuko Kakiuchi Masao Hattori Tsuneo Namba 《Phytotherapy research : PTR》1989,3(4):140-144
During the course of our studies on dental caries prevention by traditional medicines, fatty acids (myristic and oleic acids etc.) and procyanidins from betel nuts (the seed of Areca catechu L.) were respectively revealed to be the major antibacterial principles against a primary cariogenic bacterium, Streptococcus mutans, and the major inhibitory principles against glucosyltransferase from S. mutans. 相似文献
4.
Shigeki Ohgitani Akimitsu Miyauchi Yasuyuki Takagi Yoshio Fujii Takuo Fujita Misa Nakamura Zhi-qiang Zhang Liang Shan Mitsuyo Sasaki Ryuichi Tsukino Toyoharu Yokoi Kennichi Kakudo Tomitaka Nakayama Junya Toguchida Hiroshi Kanoe Shinichi Aizawa Masao S. Sasaki Takashi Nakamura M. Suda K. Tanaka Y. Ogawa N. Tamura A. Yasoda H. Itoh M. Uehira N. Nishimoto T. Takigawa K. Shiota K. Nakao 《Journal of bone and mineral metabolism》1997,15(3):165-171
5.
Haruhisa Matsuguma Rie Nakahara Masaki Anraku Tetsuro Kondo Yukio Tsuura Yukari Kamiyama Kiyoshi Mori Kohei Yokoi 《European journal of cardio-thoracic surgery》2004,25(6):1102-1106
Objective: The standard operation for patients with stage IA lung adenocarcinoma is considered to be a lobectomy. Recently, some researchers have reported that patients with tumors showing greater proportions of ground-glass opacity (GGO) at computed tomography (CT) could be candidates for limited resection, because of its less aggressive nature. However, the lack of a precise definition or standard measuring method of GGO prevents its general use as an index for planning limited resection. Therefore, we attempted to define GGO based on CT number and measured it more objectively. Methods: Between 1998 and 2001, 90 patients with clinical stage IA adenocarcinoma, who underwent standard or intentional limited resection and whose images of chest high-resolution CT were preserved in Digital Imaging and Communications in Medicine (DICOM) format, constituted the study population. The tumor shadow seen on the solid window (WL, −160 HU; WW, 2 HU) was regarded as the central solid area of the tumor seen on the lung window, and GGO was defined as the whole tumor area with the exception of the central solid area. Each area was measured using Scion Image (Scion Corp., Frederick, MD). We analyzed the relationship between the proportion of GGO and both of pathologic findings and recurrence. Results: Among the 90 tumors, 31 (34.4%) were calculated to have a GGO area greater than or equal to 50%. Of these, 27 (87%) tumors were bronchioloalveolar carcinoma. Lymphatic and vascular invasions, or nodal involvement were found only in patients with a smaller proportion of GGO (<50%) (P<0.05). During the follow-up period (median 36 months), recurrences occurred in eight patients who were diagnosed as having tumors showing smaller proportion of GGO (<50%). Conclusions: Tumors with a greater proportion of GGO measured by our method are thought to have a less invasive nature. Our objective measuring method of GGO could be useful for future multicenter trials to elucidate the value of limited resection for clinical stage IA adenocarcinoma based on the proportion of GGO. 相似文献
6.
Yasunori Cho Satoru Suzuki Masakazu Yokoi Muneaki Shimada Saburo Kuwabara Akira Murayama 《The Japanese Journal of Thoracic and Cardiovascular Surgery》2004,52(10):476-479
Lymphoblastic lymphoma, an aggressive mediastinal mass, is recognized as serious threat to the patient in developing cardiac
tamponade or airway obstruction. Surgical procedure is often required to relieve clinical emergency and to establish prompt
pathological diagnosis. However, in such a patient, acute respiratory occlusion in the spine position can be a life-threatening
complication during general anesthesia. We describe a 17-year-old man whose cardiac tamponade was treated by pericardial-pleural
window through a left anterior thoracotomy in the lateral position. The patient recovered from hemodynamic compromise without
showing respiratory occlusion during general anesthesia and remained in the lateral position until extubation. Pathological
diagnosis was precursor T-lymphoblastic lymphoma. There were no complications attributable to the operative procedure. Further
chemotherapy reduced the mediastinal mass in size after two weeks when the patient developed sepsis and died. Lateral position
prevents respiratory occlusion during surgical procedure under general anesthesia in the patient of huge anterior mediastinal
tumor with airway obstruction. 相似文献
7.
RTI-121 and RTI-122 are 3 beta-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. [123I]RTI-121 and [123I]RTI-122 bind to dopamine transporters in vivo after intravenous administration and permit imaging of the transporters. 相似文献
8.
9.
Nobuko Shiraiwa Toshihiro Yoshizawa Norio Ohkoshi Akira Tamaoka 《Clinical neurology》2007,47(4):169-172
A 17-year-old boy with high fever, headache, and neck stiffness was admitted to our hospital. Spinal fluid showed a protein level of 215 mg/dL with myelin basic protein (579 pg/mL), 347/ microl cells (330 mononuclear cells), and a glucose level of 53 mg/dL. One week later, urinary retention, flaccid paraplegia, and sensory disturbance below the 10th thoracic level developed. MRI of the spinal cord revealed swelling and T2-high intensity area in the cord at the 11th and 12th thoracic level. Although high-dose of methylprednisolone was administered, consciousness disturbance and respiratory failure that required mechanical ventilation occurred. Bilateral abducens nerve palsy, nystagmus, and flaccid tetraparesis also occurred. Brain MRI revealed T2-high intensity area in the midbrain and pons. Nerve conduction study showed diminished amplitudes and prolonged latencies or absence of F waves. The patient was administered a combination of intravenous immunoglobulin and a high-dose of methylprednisolone. He showed improvement within one week after the treatment. Two weeks later, he recovered from respiratory failure and weakness of the upper limbs. He remained paraplegic, but gradually improved and was able to walk with support one and a half years later. We suggest the combination therapy of intravenous immunoglobulin and a high-dose of methylprednisolone is effective for patients with combined ADEM and peripheral neuropathy. 相似文献
10.
H Kishimoto O Takazu S Ohno T Yamaguchi H Fujita H Kuwahara T Ishii M Matsushita S Yokoi M Iio 《Psychiatry research》1987,22(1):81-88
The authors used positron emission tomography (PET) and 11C-labeled glucose to study 15 unmedicated patients with affective disorders and 7 control subjects. Diagnoses of affective disorders were based on DSM-III criteria, and symptomatology was evaluated by the Hamilton Rating Scale for Depression. Blood counts of 11C in both unipolar and bipolar patients did not differ from those in controls after oral administration of 11C-glucose. By contrast, brain counts of 11C in unipolar depressed patients were significantly lower, whereas those in bipolar manic patients were significantly higher, than in normal controls. 相似文献