全文获取类型
收费全文 | 172篇 |
免费 | 12篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 7篇 |
妇产科学 | 3篇 |
基础医学 | 6篇 |
口腔科学 | 6篇 |
临床医学 | 15篇 |
内科学 | 68篇 |
皮肤病学 | 1篇 |
神经病学 | 9篇 |
特种医学 | 2篇 |
外科学 | 20篇 |
综合类 | 17篇 |
预防医学 | 12篇 |
眼科学 | 5篇 |
药学 | 5篇 |
中国医学 | 9篇 |
肿瘤学 | 5篇 |
出版年
2024年 | 1篇 |
2023年 | 1篇 |
2022年 | 2篇 |
2021年 | 4篇 |
2020年 | 1篇 |
2019年 | 13篇 |
2018年 | 12篇 |
2017年 | 6篇 |
2016年 | 5篇 |
2015年 | 4篇 |
2014年 | 13篇 |
2013年 | 12篇 |
2012年 | 6篇 |
2011年 | 8篇 |
2010年 | 5篇 |
2009年 | 5篇 |
2008年 | 6篇 |
2007年 | 10篇 |
2006年 | 9篇 |
2005年 | 11篇 |
2004年 | 7篇 |
2003年 | 9篇 |
2002年 | 15篇 |
2001年 | 8篇 |
2000年 | 8篇 |
1999年 | 3篇 |
1997年 | 1篇 |
1990年 | 2篇 |
1989年 | 3篇 |
排序方式: 共有190条查询结果,搜索用时 46 毫秒
1.
2.
A 56 year old patient who developed acute pancreatitis following intrabiliary rupture of a hydatic cyst of the liver is reported herein. Hepatic hydatic disease is a very rare cause of acute pancreatitis for which the surgical treatment consists of evacuation of the cyst material and biliary drainage. Cystoenteric drainage is not mandatory. 相似文献
3.
Nadir Y?net?i Nevin Oru? A Omer Ozütemiz Kamil Kumanlioglu Gül Yüce Yücel Batur 《Experimental and toxicologic pathology》2002,54(3):197-201
BACKGROUND: Many interrelationships exist between the thyroid gland and the gastrointestinal tract. Several past and recent studies have shown that the thyroid gland profoundly influences the structure and function of the exocrine pancreas in the rat. In the present study we investigated the effect of methimazole (METZ), an antithyroid drug, on cerulein induced acute pancreatitis (AP) in rats. METHODS: Rats were divided into 3 groups (10-12 weeks age, 200-250 g weight, n: 10). Group B was made hypothyroid with methimazole 5 mg/kg daily for 10 days and the others were untreated euthyroid groups. After 10 days, acute pancreatitis was induced with four doses of 20 microg/kg body weight of cerulein administered s.c at hourly intervals in group A and B while the control group C was given 4 doses of I ml saline. Pancreas wet weight (mg), plasma amylase activity (IU/l) and pancreatic histology were used as endpoints to quantify the severity of the AP. RESULTS: Plasma tri-iodothyronine (T3) (ng/dl) and thyroxine (T4) (microg/dl) levels were significantly reduced after METZ treatment for 10 days (p < 0.01). METZ pretreatment reduced significantly the cerulein induced increase in pancreatic weight (1,205 +/- 12 mg in METZ treated AP group versus 1,617 +/- 14 mg in AP group, p < 0.05) and the rise in amylase activity (7,078 +/- 816 IU/l in METZ treated AP group versus 8,611 +/- 830 IU/l in AP group p < 0.05). CONCLUSION: METZ reduces the severity of cerulein induced AP in rats. This effect might be through its antithyroid property. 相似文献
4.
A. Elif Anil Berna B. Kivircik Senar Batur Elif Kabakçi Arzu Kitis Ersen Güven 《The Clinical neuropsychologist》2013,27(2):159-169
The following study was conducted to adapt the Auditory Consonant Trigram Test (ACT) to Turkish, acquire a new and larger set of normative data, and finally investigate the reliability and validity of the adapted version. The data were collected from a sample of 236 healthy individuals. To test the validity of the Turkish version of ACT, the normative results of ACT were first compared with those obtained from the Digit Span Test (DST) backwards section. Secondly, the ACT performance of 53 schizophrenic patients was compared with that of a matched group selected from the normative sample. Age and education variables influenced performance, whereas gender did not in the normal sample. The ACT and DST backwards scores were positively correlated. As expected, the ACT performance was worse in schizophrenic patients compared to controls. The internal consistency of the adapted version of ACT was found to be at a reliable level (a=0.8535). The Turkish version of ACT can be considered to be a reliable and valid measure of working memory. 相似文献
5.
6.
Eli M Li DS Zhang WW Kong B Du CS Wumar M Mamtimin B Sheyhidin I Hasim A 《World journal of gastroenterology : WJG》2012,18(24):3112-3118
AIM: To investigate the relationship between blood riboflavin levels and riboflavin transporter 2 (RFT2) gene expression in gastric carcinoma (GC) development.METHODS: High-performance liquid chromatography was used to detect blood riboflavin levels in patients with GC. Real-time fluorogenic quantitative polymerase chain reaction and immunohistochemistry were used to analyze the expression of RFT2 mRNA and protein in samples from 60 GC patients consisting of both tumor and normal tissue.RESULTS: A significant decrease in the RFT2 mRNA levels was detected in GC samples compared with those in the normal mucous membrane (0.398 ± 0.149 vs 1.479 ± 0.587; P = 0.040). Tumors exhibited low RFT2 protein expression (75%, 16.7%, 8.3% and 0% for no RFT2 staining, weak staining, medium staining and strong staining, respectively), which was significantly lower than that in the normal mucous membrane (10%, 16.7%, 26.7% and 46.7% for no RFT2 staining, weak staining, medium staining and strong staining, respectively; P < 0.05). Tumors with low RFT2 expression were significantly associated with tumor stage and histological grade. Moreover, a significantly decrease in Uyghur patients was observed compared with Han patients. However, other parameters-gender, tumor location and lymph node metastasis-showed no significant relationship with RFT2 expression. Blood riboflavin levels were reverse correlated with development of GC (1.2000 ± 0.97 569 ng/mL in high tumor stage patients vs 2.5980 ± 1.31 129 ng/mL in low tumor stage patients; P < 0.05). A positive correlation of plasma riboflavin levels with defective expression of RFT2 protein was found in GC patients (χ2 = 2.619; P = 0.019).CONCLUSION: Defective expression of RFT2 is associated with the development of GC and this may represent a mechanism underlying the decreased plasma riboflavin levels in GC. 相似文献
7.
8.
A. Altunoglu D. Yavuz M. Batur Canoz R. Yavuz Latife A. Karakaş N. Bayraktar T. Colak S. Sezer F. Nurhan Ozdemir M. Haberal 《Transplantation proceedings》2014
Background
Patients with end-stage renal disease (ESRD) experience female sexual dysfunction (FSD). The purpose of this study was to compare FSD in different types of renal replacement therapy and control patients.Methods
The study was consisted of 47 renal transplantation (RT), 46 hemodialysis (HD), and 28 continuous ambulatory peritoneal dialysis (CAPD) patients and 36 healthy control subjects. All groups were evaluated with the following scales: Female Sexual Function Index (FSFI) questionnaire, Short Form (SF)–36 questionnaires, and Beck Depression Inventory (BDI). Demographic data, laboratory values, and hormone levels were obtained. The patients with FSFI score <26.55 were accepted as experiencing sexual dysfunction.Results
Overall, total FSFI scores in RT, HD, CAPD, and control were 22 (range, 2–35), 22.4 (4–34), 18.35 (2–34), and 29.6 (2–35), respectively. The mean total FSFI score was not different in patients receiving different kinds of renal replacement therapy (P > .05) although they were significantly worse then the control group (P < .001). On regression analysis, age was significantly associated with FSD (β = −0.14; P = .001). In addition, the physiologic health domain of SF-36 was significantly better in control groups (P < .001). The difference in terms of mean of BDI score did not reach statistical significance among patient groups (P > .05). Female sexual dysfunction score was negatively correlated with BDI (r = −0.371; P < .001) and positively correlated with the mental-physical components score of SF-36 (r = 0.423 [P < .001] and r = 0.494 [P < .001], respectively) in all patients groups. Regarding the hormones of the patients, there was a significant difference between RT and the HD and CAPD groups in dihydroepiandrosterone sulfate (DHEAS; P < .001), RT and HD in prolactin (P < .001), and RT and CAPD in free testesterone (P < .001).Conclusions
Renal transplantation, hemodialysis, and peritoneal dialysis patients were at more risk of developing sexual dysfunction and lower quality of life scores than healthy subjects. Notably, the mode of renal replacement therapy had no impact on female sexual function. 相似文献9.
10.
Ozer S Uluşahin A Batur S Kabakçi E Saka MC 《Social psychiatry and psychiatric epidemiology》2002,37(1):31-37
Background We aimed to study the correlations of several outcome measures in bipolar patients with the clinical features of interepisode
period. Methods Bipolar patients who were diagnosed according to DSM-III-R or IV were contacted and asked for a further evaluation. Interepisode
bipolar patients (n = 100) were interviewed with the Schedule for Affective Disorders and Schizophrenia (SADS). In addition
the Brief Disability Questionnaire (BDQ), the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) and the Global
Assessment Scale (GAS) were administered to assess outcome. They were also asked to check the List of Life Events (LLE) for
the last six months. Results Our results can be summarised as follows: (1) quality of life was predicted by current subthreshold depressive symptoms;
(2) the number of previous depressive episodes, current subthreshold depressive and manic symptoms predicted disability; (3)
the number of previous depressive episodes and the duration of hospitalisation as well as current subthreshold depressive
and manic symptoms predicted overall functioning; (4) the number and distress level of life events were correlated with suicidal
symptoms. Conclusions Our findings suggest that outcome measures were correlated with subsyndromal disorder, the number of previous depressive
episodes and the duration of hospitalisation.
Accepted: 2 October 2001 相似文献