全文获取类型
收费全文 | 7770篇 |
免费 | 589篇 |
国内免费 | 81篇 |
专业分类
耳鼻咽喉 | 65篇 |
儿科学 | 173篇 |
妇产科学 | 352篇 |
基础医学 | 926篇 |
口腔科学 | 106篇 |
临床医学 | 904篇 |
内科学 | 1762篇 |
皮肤病学 | 83篇 |
神经病学 | 549篇 |
特种医学 | 525篇 |
外科学 | 970篇 |
综合类 | 159篇 |
一般理论 | 3篇 |
预防医学 | 376篇 |
眼科学 | 157篇 |
药学 | 552篇 |
中国医学 | 45篇 |
肿瘤学 | 733篇 |
出版年
2023年 | 40篇 |
2022年 | 29篇 |
2021年 | 194篇 |
2020年 | 99篇 |
2019年 | 166篇 |
2018年 | 232篇 |
2017年 | 159篇 |
2016年 | 142篇 |
2015年 | 241篇 |
2014年 | 310篇 |
2013年 | 404篇 |
2012年 | 582篇 |
2011年 | 538篇 |
2010年 | 320篇 |
2009年 | 345篇 |
2008年 | 468篇 |
2007年 | 397篇 |
2006年 | 389篇 |
2005年 | 404篇 |
2004年 | 380篇 |
2003年 | 312篇 |
2002年 | 263篇 |
2001年 | 237篇 |
2000年 | 195篇 |
1999年 | 201篇 |
1998年 | 88篇 |
1997年 | 51篇 |
1996年 | 51篇 |
1995年 | 56篇 |
1994年 | 46篇 |
1993年 | 36篇 |
1992年 | 108篇 |
1991年 | 79篇 |
1990年 | 80篇 |
1989年 | 65篇 |
1988年 | 77篇 |
1987年 | 75篇 |
1986年 | 69篇 |
1985年 | 68篇 |
1984年 | 68篇 |
1983年 | 36篇 |
1982年 | 29篇 |
1980年 | 18篇 |
1979年 | 39篇 |
1978年 | 31篇 |
1977年 | 25篇 |
1976年 | 18篇 |
1975年 | 36篇 |
1974年 | 24篇 |
1973年 | 19篇 |
排序方式: 共有8440条查询结果,搜索用时 46 毫秒
1.
2.
3.
Christopher Yeh Cem Atillasoy John T. Seykora Vivian Lee 《Journal of cutaneous pathology》2021,48(1):171-173
Respiratory cysts are benign lesions lined by normal respiratory epithelium. There are few reported cases localized to the orbit, while those of the eyelid are exceedingly rare. Respiratory cysts usually arise either from a non‐hereditary congenital malformation, where they are distinguished as choristomatous, or from trauma. Here, we report a case of a 53‐year‐old man who presented with a large right lower eyelid cyst that was histopathologically diagnosed as a respiratory cyst. 相似文献
4.
Acid-suppressive drugs, including histamine-2 receptor antagonists (H2RAs) and proton pump inhibitors (PPIs), are common medications used for treating upper gastrointestinal tract disorders. However, acid-suppressive drugs have been reported to increase the risk of pneumonia in numerous disease populations. However, the relationship between acid-suppressive drugs and stroke-associated pneumonia (SAP) remains controversial.The purpose of this study was to investigate the association between acid-suppressive drug usage and pneumonia among patients with stroke by using a nationwide data set.A population-based cohort study was conducted using a data set from the Taiwanese National Health Insurance Research Database. Data on patients with new-onset stroke from 2010 to 2011 were collected. Patients with and without acid-suppressive drug usage were followed up to identify the occurrence of any type of pneumonia. We estimated the adjusted hazard ratios (HRs) by using the Cox proportional hazards model.The study cohort comprised 7965 patients with new-onset stroke. The incidence of pneumonia was 6.9% (552/7965) and more than 40% (225/552) of patients developed pneumonia within 3 months after an acute stroke. Acid-suppressive drug usage was an independent risk factor of pneumonia. The adjusted HR for the risk of pneumonia in patients with new-onset stroke using acid-suppressive drugs was 1.44 (95% confidence interval [CI] = 1.18–1.75, P < 0.01). Only PPI usage increased risk of chronic SAP (adjusted HR = 1.46, 95% CI = 1.04–2.05).Acid-suppressive drug usage was associated with a slightly increased risk of SAP. Physicians should exercise caution when prescribing acid-suppressive drugs to patients with stroke, particularly at the chronic stage. 相似文献
5.
6.
Intratemporal vascular tumors: detection with CT and MR imaging 总被引:1,自引:0,他引:1
Lo WW; Shelton C; Waluch V; Solti-Bohman LG; Carberry JN; Brackmann DE; Wade CT 《Radiology》1989,171(2):445-448
The diagnostic contributions of computed tomography (CT) and magnetic resonance (MR) imaging were compared in 12 patients with benign intratemporal vascular tumors (hemangioma or vascular malformation). The tumors included six in the internal acoustic canal and six in the geniculate ganglion region. Clinical and histologic correlations were made. Two of the six patients with tumors in the internal acoustic canal underwent CT, and both required gas cisternography to show the tumor. Five patients in that group underwent MR imaging, and all five studies showed the tumor. All six patients with geniculate ganglion tumors underwent CT. Results in one study were questionable, and five showed the tumor. Five patients in this group underwent MR imaging, but the MR findings were positive in only two cases. MR imaging should therefore be performed before CT in the evaluation of facial nerve dysfunction, as it demonstrated all tumors in the internal acoustic canal and some in the geniculate ganglion region. If MR findings are negative, CT should then be performed to rule out a possible geniculate ganglion lesion. 相似文献
7.
Meng-Luen Lee Lon-Yen Tsao Wun-Tsong Chaou Albert D Yang Kun-Tu Yeh Jou-Kou Wang Mei-Hwan Wu Hung-Chi Lue Ing-Sh Chiu Chung-I Chang 《Pediatric pulmonology》2002,33(1):1-11
We propose a haphazard branching theory to support the concept of bronchopulmonary malinosculations, and we apply this theory to classify congenital bronchopulmonary vascular malformation (BPVM) based on the anatomical results we have found. Between January 1990 and December 1997, a total of 22 pediatric patients (10 male and 12 female), aged 2 days to 14 years (median, 19.6 months), with congenital BPVM were enrolled in this retrospective study. Study modalities include the clinical features and plain chest films (n = 22) plus at least two of the following: echocardiography (n = 13), barium esophagraphy (n = 2), bronchoscopy (n = 4), contrast bronchography (n = 8), high-resolution direct coronal CT (n = 1) and electron beam or ultrafast CT (n = 1) of the chest, MRI (n = 10), MRA (n = 1), contrast cineangiocardiography (n = 9), surgery (n = 11), or autopsy (n = 2). The salient clinical features were recurrent lung infections in 14 patients, acute respiratory distress in 13, associated cardiovascular malformations in 8, dextroversion in 7, congestive heart failure in 7, dextrocardia in 4, and complex congenital heart diseases in 4. There were abnormal openings (malinosculations) of the pulmonary airway in 20 patients: to an artery in 12, to a vein in 8, and to the lung parenchyma in 9. These 22 patients with congenital BPVM can be classified into bronchial malinosculation (10 cases), arterial malinosculation (2 cases), and bronchoarterial malinosculation (10 cases). Congenital BPVM can be classified in terms of bronchopulmonary malinosculation based upon a haphazard branching theory, in which abnormal communications between two independent systems (primitive foregut system and aortic-pulmonary arch system) occurred coincidentally rather than causally. 相似文献
8.
Therapy of human cervical carcinoma with monoclonal antibody-Pseudomonas exotoxin conjugates. 总被引:1,自引:0,他引:1
Pseudomonas exotoxin A (PE) linked to the F(ab')2 fragment of 1H10, a murine monoclonal antibody recognizing a carbohydrate epitope of a glycoconjugate expressed on the surface of human cervical carcinoma tumor cells, was evaluated for in vitro and in vivo activity. PE can kill cells by ADP-ribosylating elongation factor 2 thus inhibiting protein synthesis. Disulfide- as well as thioether-linked immunotoxins (1H10-PE) killed cervical carcinoma cells in vitro and were 20-160 times more inhibitory to target than to control cells. Cell killing was antibody mediated as demonstrated by the reduction of 1H10-PE growth inhibition to target CaSki cells by free 1H10 F(ab')2. In addition, a control antibody immunotoxin was nontoxic to CaSki cells. Thioether-linked 1H10-PE administered either i.v. or i.p. suppressed the growth of established solid s.c. cervical carcinoma tumors xenografted in nude mice for over 30 days. Treatment with antibody alone or a control immunotoxin had no significant effect on tumor growth. Administration of immunotoxin i.p. was associated with less toxicity than administration i.v., but i.v. injections were more effective at suppressing the growth of established solid tumors. 相似文献
9.
目的:评价螺旋CT在诊断肺动脉栓塞中的作用。方法:16例肺动脉栓塞患者行螺旋CT肺动脉造影 (SCTA)检查,层厚3mm,扫描时间0.8s,对比剂注射速度3.5ml/s,总量100ml,扫描延迟时间15s。结果:16例 共644支,其中134支肺动脉及分支显示了栓塞,占20.8%。228支肺段肺动脉中,有56支显示肺动脉栓塞,占分 析肺动脉支的24.5%。204支亚段肺动脉中37支显示肺动脉栓塞,占分析肺动脉支15.4%。肺动脉栓塞的CT形 态:①直接征象为不同程度的肺动脉分支内充盈缺损。中心型充盈缺损17支,偏心型充盈缺损44支,附壁血栓型 34支,完全阻塞型39支。②间接征象胸膜下肺梗死灶,内乳动脉一侧增粗,肺纹理稀少,胸水,肺动脉高压。结论: 螺旋CT肺动脉造影是诊断肺动脉栓塞的快速、有效、无创伤的诊断方法。 相似文献
10.