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Medical care activities of full-time health departments 总被引:5,自引:0,他引:5
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This report deals with the effect of purified HSPI (10.7 kDa single chain prostatic peptide of 94 amino acids) on PHA-stimulated proliferation of peripheral blood mononuclear cells (PBMNC). HSPI was found to inhibit the incorporation of 3H-thymidine by PHA-stimulated PBMNC in a dose-dependent manner, albeit with the requisite of pretreatment of cells with HSPI. A maximum inhibition was observed on pretreatment for 30 min. These studies thus indicate that HSPI may be interfering with the very early events of PHA-induced signal transduction process in PBMNC. 相似文献
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Sokolova IN Savelov NA Chistiakova OV Sorokin KV Gurariĭ LL Shatinina NN 《Arkhiv patologii》2005,67(6):38-43
59 angiomyolipomas were studied: immunohistochemistry (IHC) was used in 24 cases, electron microscopy (EM) in 6 cases. 57 tumors had a typical structure, 2 did not contain fat component. Premelanosomes were found by EM in one tumor. Smooth muscle actin was found in all tumor cells. Involvement of lymph nodes was observed in 2 patients. Histogenesis of this tumor is discussed. 相似文献
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Morphology of microparticles of the microencapsulated measles vaccine was studied by cryofractography, transmission electronic microscopy and by atomic force microscopy; co-polymers of polyacrylic acid and of sodium-alginate (spermidine) complexes were used as the matrix. The different-composition microcapsules had clear-cut borders and a certain range of sizes; but they were different in morphology, and their structures and densities varied identically with regard for a medium acidity, which is apparently preconditioned by some conformation-type alterations of matrix molecules. The studied preparations can, probably, protect the viral material in the stomach aggressive medium and release the material to ensure its contact with the intestine lymph tissue; thereof, they can be referred to as promising for further study of mucosal vaccines. 相似文献
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Petrovich IuA Podorozhnaia RP Terekhina NA Kichenko SM Dmitriev IM 《Patologicheskaia fiziologiia i èksperimental'naia terapiia》2003,(3):19-21
A new bone/blood index has been developed which is calculated by dividing % of radionuclide inclusion in the bones by % of the inclusion in the serum. Graphic image of the index changes with time is significantly more demonstrative than digital tables and allows one not only easily measure distribution of the labelled compound between fractions diluted in the blood and sorbed on the bone but also specify a major direction of their transport between blood and bone. The index confirms the presence of biphasic primary fast but weak physical adsorption and secondary slow and strong chemisorption. This was established by the study of time course of the labelled citrate in intact rats of different age as well as in fracture and bone innervation defect, in rickets and dental caries. The proposed index can be applied in investigation of various diseases. 相似文献