全文获取类型
收费全文 | 35742篇 |
免费 | 2213篇 |
国内免费 | 327篇 |
专业分类
耳鼻咽喉 | 315篇 |
儿科学 | 954篇 |
妇产科学 | 785篇 |
基础医学 | 4123篇 |
口腔科学 | 1011篇 |
临床医学 | 3335篇 |
内科学 | 8935篇 |
皮肤病学 | 576篇 |
神经病学 | 3620篇 |
特种医学 | 1329篇 |
外科学 | 5296篇 |
综合类 | 126篇 |
现状与发展 | 1篇 |
一般理论 | 19篇 |
预防医学 | 1913篇 |
眼科学 | 585篇 |
药学 | 2106篇 |
中国医学 | 42篇 |
肿瘤学 | 3211篇 |
出版年
2023年 | 327篇 |
2022年 | 356篇 |
2021年 | 1310篇 |
2020年 | 746篇 |
2019年 | 1092篇 |
2018年 | 1233篇 |
2017年 | 976篇 |
2016年 | 977篇 |
2015年 | 1141篇 |
2014年 | 1530篇 |
2013年 | 1903篇 |
2012年 | 2815篇 |
2011年 | 2918篇 |
2010年 | 1541篇 |
2009年 | 1417篇 |
2008年 | 2430篇 |
2007年 | 2332篇 |
2006年 | 2127篇 |
2005年 | 2098篇 |
2004年 | 1964篇 |
2003年 | 1721篇 |
2002年 | 1588篇 |
2001年 | 306篇 |
2000年 | 254篇 |
1999年 | 304篇 |
1998年 | 314篇 |
1997年 | 241篇 |
1996年 | 229篇 |
1995年 | 226篇 |
1994年 | 168篇 |
1993年 | 158篇 |
1992年 | 143篇 |
1991年 | 125篇 |
1990年 | 132篇 |
1989年 | 114篇 |
1988年 | 90篇 |
1987年 | 92篇 |
1986年 | 82篇 |
1985年 | 86篇 |
1984年 | 74篇 |
1983年 | 63篇 |
1982年 | 61篇 |
1981年 | 51篇 |
1980年 | 36篇 |
1979年 | 70篇 |
1978年 | 34篇 |
1977年 | 34篇 |
1976年 | 30篇 |
1975年 | 30篇 |
1974年 | 24篇 |
排序方式: 共有10000条查询结果,搜索用时 265 毫秒
1.
2.
Exhaled nitric oxide in children with allergic rhinitis: A potential biomarker of asthma development 下载免费PDF全文
3.
Carlo De-Carolis Geraldine-A. Boyd Luca Mancinelli Stefano Pagano Stefano Eramo 《Medicina oral, patología oral y cirugía bucal》2015,20(2):e205-e210
With easy chemical synthesis from its precursor, methamphetamine (MA) is now widespread in many countries. The abuse of methamphetamine is associated with several negative effects on health, because MA is a neurotoxin and a dangerous central nervous system stimulant. It changes levels of neurotransmitters in the brain, releasing dopamine and inhibiting nor epinephrine uptake which increases sympathetic nervous system activity and can lead to cardiac arrhythmia, hypertension and tachypnea. The consequences of MA abuse are clearly manifested in oral diseases (like “meth mouth”) which is characterised by extensive caries, teeth grinding with ensuing dental wear and trismus. The present review was designed to fill the gap in knowledge about methamphetamine abuse in the European Union (EU) and to illustrate the main clinical effects of prolonged use. After describing the pharmacology and systemic effects of methamphetamine and concentrating on its effects on the mouth, the present review compares the epidemiology and incidence of abuse in the world, particularly the USA and the EU.
Key words:Methamphetamine, “Meth mouth”, drug abuse, oral health. 相似文献
4.
5.
6.
Gian Eugenio Tontini Guido Manfredi Stefania Orlando Helmut Neumann Maurizio Vecchi Elisabetta Buscarini Luca Elli 《Digestive endoscopy》2019,31(6):627-643
Over the last decade, impressive technological advances have occurred in ultrasonography and small‐bowel endoscopy. Nowadays, endoscopic ultrasonography is an essential diagnostic tool and a therapeutic weapon for pancreatobiliary disorders. Capsule endoscopy and device‐assisted enteroscopy have quickly become the reference standard for the diagnosis of small‐bowel luminal diseases, thereby leading to radical changes in diagnostic and therapeutic pathways. We herein provide an up‐to‐date overview of the latest advances in endoscopic ultrasonography and small‐bowel endoscopy, focusing on the emerging paradigms and technological innovations that might improve clinical practice in the near future. 相似文献
7.
8.
9.
10.
Erika Cecon Anna Ivanova Marine Luka Florence Gbahou Anne Friederich Jean‐Luc Guillaume Patrick Keller Klaus Knoch Raise Ahmad Philippe Delagrange Michele Solimena Ralf Jockers 《Journal of pineal research》2019,66(2)
Melatonin receptors play important roles in the regulation of circadian and seasonal rhythms, sleep, retinal functions, the immune system, depression, and type 2 diabetes development. Melatonin receptors are approved drug targets for insomnia, non‐24‐hour sleep‐wake disorders, and major depressive disorders. In mammals, two melatonin receptors (MTRs) exist, MT1 and MT2, belonging to the G protein‐coupled receptor (GPCR) superfamily. Similar to most other GPCRs, reliable antibodies recognizing melatonin receptors proved to be difficult to obtain. Here, we describe the development of the first monoclonal antibodies (mABs) for mouse MT1 and MT2. Purified antibodies were extensively characterized for specific reactivity with mouse, rat, and human MT1 and MT2 by Western blot, immunoprecipitation, immunofluorescence, and proximity ligation assay. Several mABs were specific for either mouse MT1 or MT2. None of the mABs cross‐reacted with rat MTRs, and some were able to react with human MTRs. The specificity of the selected mABs was validated by immunofluorescence microscopy in three established locations (retina, suprachiasmatic nuclei, pituitary gland) for MTR expression in mice using MTR‐KO mice as control. MT2 expression was not detected in mouse insulinoma MIN6 cells or pancreatic beta‐cells. Collectively, we report the first monoclonal antibodies recognizing recombinant and native mouse melatonin receptors that will be valuable tools for future studies. 相似文献