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排序方式: 共有236条查询结果,搜索用时 125 毫秒
1.
Erkan Yildirim Erkan Kaptanoglu Kanat Ozisik Ethem Beskonakli Ozerk Okutan Mustafa F Sargon Kamer Kilinc Unal Sakinci 《European journal of cardio-thoracic surgery》2004,25(4):523-529
OBJECTIVE: We aimed to demonstrate the time-dependent ultrastructural changes in pneumocyte type II cells following brain injury, and to propose an electron microscopic scoring model for the damage. METHODS: Forty Wistar-Albino female rats weighing 170-200 g were used. The rats were allocated into five groups. The first group was the control and the second was the craniotomy without trauma. The others were trauma groups. Weight-drop method was used for achieving head trauma. Samples were obtained from the right and left pulmonary lobes at 2-, 8-, and 24-h intervals after transcardiac perfusion. An electron microscopic scoring model was used to reveal the changes. RESULTS: There were no ultrastructural pathological findings pointing to lung injury in any rat of the control groups. There was intense intracellular oedema in type II pneumocyte and interstitial oedema in the adjacent tissue in trauma groups. Oedema in mitochondria and dilatation in both smooth endoplasmic reticulum and Golgi apparatus was more evident in the 8- and 24-h trauma groups. The chromatin dispersion was disintegrated in the nucleus in all trauma groups. Scores of all trauma groups were significantly different from the controls (P<0.05). All trauma groups were different from each other at significant levels (P<0.05 for each trauma groups). CONCLUSIONS: The data suggested that ultrastructural damage is obvious at 2 h and deteriorates with time. The electron microscopic scoring model worked well in depicting the traumatic changes, which were supported by lipid peroxidation. Further experiments are needed to determine the exact outcome after brain death model. 相似文献
2.
Meredith M Hancock Colette C Prosser Kanat Ransibrahmanakul Laura Lester Elana Craemer James A Bourgeois Lorenzo Rossaro 《Substance abuse treatment, prevention, and policy》2007,2(1):5
Methadone maintenance therapy for the treatment of opioid dependence continues to carry a social stigma. Until recently, patients
on methadone were not considered for liver transplantation. We describe the first case of a patient on methadone who received
a liver transplant for end stage liver disease and was successfully treated for recurrent hepatitis C. More than five years
post transplant and three years post viral clearance, the patient continues to do well and is stable on low-dose methadone.
This case emphasizes the need to reconsider the non-evidence based policy adopted by transplant centers that require methadone
maintenance therapy patients to stop methadone prior to consideration for transplant evaluation. 相似文献
3.
The effect of calcium dobesilate on venous function following saphenectomy in coronary artery bypass grafting 总被引:1,自引:0,他引:1
Kerim Cagli Kanat Ozisik Mustafa Emir Okan Yurdakok Sami Gurkahraman Vedat Bakuy Muharrem Tola Mustafa Pac Adnan Cobanoglu 《Cardiovascular Revascularization Medicine》2006,7(4):212-216
BACKGROUND: The aim of this study was to determine whether prophylactic use of calcium dobesilate (CD) can improve venous function after saphenous vein harvest in coronary artery bypass graft (CABG). MATERIALS AND METHODS: A total of 100 patients who underwent elective CABG were divided into four equal groups. In Group A, the greater saphenous vein (GSV) was harvested below the knee and, in Group B, through the knee till the groin. These patients remained untreated. Group C received CD in a dosage of 1500 mg po daily after the GSV was harvested below the knee. Group D received same dosage of CD after the GSV was harvested through the knee till the groin. Venous function of ipsilateral leg was evaluated clinically and by Doppler ultrasonography in the postoperative first week and second month. RESULTS: Clinical findings of venous insufficiency were observed with a similar rate between groups at both early and late periods. In Groups A and B, after 2 months, flow velocities decreased and reflux periods increased significantly. In groups C and D, treatment with CD for 2 months after saphenectomy resulted in a significant increase in flow velocities and a significant decrease in reflux periods. Patients in Groups B and D have significantly more impaired venous functions. CONCLUSION: Saphenectomy results in ipsilateral leg venous dysfunction, which seems to be unrelated to leg swelling and to be more prominent in patients with high-level saphenectomy. In addition, to be careful about the restriction of the saphenectomy procedure into the most appropriate level, prophylactic use of CD can prevent this deterioration when it was added to varice socks. 相似文献
4.
The rheumatoid arthritis patient often suffers with forefoot complaints. The most frequently seen pedal deformities are hallux abducto valgus and metatarsus primus adductus. Various surgical procedures have been developed to treat these disabling problems. Arthroplasty has been successfully utilized to relieve pain, but often leaves an unpleasant cosmetic result due to shortening and possible return of the deformity. Arthrodesis and implant arthroplasty are alternatives, but introduce other risks and complications for the patient and surgeon. 相似文献
5.
Mustafa Girgin Burhan Hakan Kanat Refik Ayten Ziya Cetinkaya Zekiye Kanat Ahmet Bozda? Ahmet Turkoglu Yavuz Selim Ilhan 《International surgery》2012,97(4):288-292
Pilonidal disease has been treated surgically and by various other methods for many years. The most important problem associated with such treatment is recurrence, but cosmetic outcome is another important issue that cannot be ignored. Today, crystallized phenol is recognized as a treatment option associated with good medical and cosmetic outcomes. We hypothesized that the addition of laser depilation to crystallized phenol treatment of pilonidal disease might increase the rate of success, and this study aimed to determine if the hypothesis was true. Patients who were treated with crystallized phenol and 755-nm alexandrite laser depilation were retrospectively analyzed. In total, 42 (31 male and 11 female) patients were treated with crystallized phenol and alexandrite laser depilation and were followed up between January 2009 and January 2012. In all, 38 patients (90.5%) had chronic disease and 4 (9.5%) had recurrent disease. Among the patients, 26 (61.9%) recovered following 1 crystallized phenol treatment, and the remaining patients had complete remission following repeated treatment. Some patients needed multiple treatments, even up to 8 times. None of the patients had a recurrence during a mean 24 months (range, 6–30 months) of follow-up. Whatever method of treatment is used for pilonidal disease, hair cleaning positively affects treatment outcome. The present results support the hypothesis that the addition of laser depilation (which provides more permanent and effective depilation than other methods) to crystallized phenol treatment (a non-radical, minimally invasive method associated with very good cosmetic results) can increase the effectiveness of the treatment and also reduce the recurrence rate of the disease. 相似文献
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8.
Seluk Kanat Hakan akr Ahmet Tütüncü Erhan Tenekecioglu 《Pacing and clinical electrophysiology : PACE》2019,42(3):309-312
We herein report successful cryoablation of paroxysmal atrial fibrillation via right jugular vein in a patient with interrupted inferior vena cava. We preferred cryoablation instead of radiofrequency ablation in the treatment of our patient. For stronger support in aiming the Brockenbrough needle toward the septum, we manuallly curved the needle with a 120° angle about 6 cm proximal to the tip. After successful transseptal puncture, we performed balloon dilatation in the septal puncture zone to facilitate passage. Cryoablation has theoretical advantage, particularly in challenging anatomies, in which it eliminates the need for point‐by‐point ablation around the pulmonary vein. 相似文献
9.
Dural K Han S Yildirim E Koçer B Kandemir M Ozişik K Sakinci U 《Tüberküloz ve toraks》2005,53(1):57-61
Thoracostomy tube placement (TT) is currently one of the most important treatment modalities used in traumatic pneumothorax patients. In patients with low pneumothorax ratio (percentage), both follow-up without surgery and employing intervention when indicated may be appropriate choice. We presented the outcome of patients with low traumatic pneumothorax ratio treated by follow up without surgical intervention in our clinic. During the period from January 2000 until January 2002, 108 patients who were treated and followed with low percentage traumatic pneumothorax in Ankara Numune Hospital Thoracic Surgery Clinic were allocated into three groups due to blunt trauma of the thorax, penetrating-cutting instrument injury and gunshot injury. All patients were admitted to the clinic with the purpose of observation without surgical intervention and chest roentgenograms were taken at the sixth and twelfth hours and daily thereafter. TT was performed for 46 (43%) patients whose pneumothorax ratio increased during the observation period. TT was more frequent in patients with 20% percentage pneumothorax (69%) as well as with two or more fractured ribs (69%). Follow-up without surgical intervention may one of the appropriate modes of treatment in patients who have minimal traumatic pneumothorax. 相似文献
10.
Ayhan Kanat Mehmet Sabri Balik Serkan Kirbas Bulent Ozdemir Vaner Koksal Ugur Yazar Hizir Kazdal Ahmet Kalaycioglu 《Acta neurochirurgica》2014,156(1):165-168