全文获取类型
收费全文 | 16090篇 |
免费 | 1128篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 126篇 |
儿科学 | 469篇 |
妇产科学 | 540篇 |
基础医学 | 1871篇 |
口腔科学 | 192篇 |
临床医学 | 2375篇 |
内科学 | 2936篇 |
皮肤病学 | 134篇 |
神经病学 | 1595篇 |
特种医学 | 426篇 |
外国民族医学 | 1篇 |
外科学 | 1905篇 |
综合类 | 210篇 |
一般理论 | 20篇 |
预防医学 | 2108篇 |
眼科学 | 205篇 |
药学 | 851篇 |
中国医学 | 10篇 |
肿瘤学 | 1272篇 |
出版年
2023年 | 92篇 |
2022年 | 82篇 |
2021年 | 310篇 |
2020年 | 224篇 |
2019年 | 376篇 |
2018年 | 399篇 |
2017年 | 308篇 |
2016年 | 325篇 |
2015年 | 346篇 |
2014年 | 521篇 |
2013年 | 750篇 |
2012年 | 1165篇 |
2011年 | 1139篇 |
2010年 | 636篇 |
2009年 | 613篇 |
2008年 | 1015篇 |
2007年 | 1103篇 |
2006年 | 1078篇 |
2005年 | 1064篇 |
2004年 | 952篇 |
2003年 | 1015篇 |
2002年 | 879篇 |
2001年 | 131篇 |
2000年 | 111篇 |
1999年 | 165篇 |
1998年 | 198篇 |
1997年 | 136篇 |
1996年 | 166篇 |
1995年 | 115篇 |
1994年 | 98篇 |
1993年 | 98篇 |
1992年 | 90篇 |
1991年 | 81篇 |
1990年 | 77篇 |
1989年 | 108篇 |
1988年 | 63篇 |
1987年 | 67篇 |
1986年 | 55篇 |
1985年 | 72篇 |
1984年 | 76篇 |
1983年 | 81篇 |
1982年 | 101篇 |
1981年 | 72篇 |
1980年 | 63篇 |
1979年 | 47篇 |
1978年 | 48篇 |
1976年 | 33篇 |
1975年 | 35篇 |
1973年 | 36篇 |
1970年 | 32篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Elizabeth D. Krebs Robert B. Hawkins J. Hunter Mehaffey Clifford E. Fonner Alan M. Speir Mohammed A. Quader Jeffrey B. Rich Leora T. Yarboro Nicholas R. Teman Gorav Ailawadi 《The Journal of thoracic and cardiovascular surgery》2019,157(4):1533-1542.e2
Objectives
Expedient extubation after cardiac surgery has been associated with improved outcomes, leading to postoperative extubation frequently during overnight hours. However, recent evidence in a mixed medical-surgical intensive care unit population demonstrated worse outcomes with overnight extubation. This study investigated the impact of overnight extubation in a statewide, multicenter Society of Thoracic Surgeons database.Methods
Records from 39,812 patients undergoing coronary artery bypass grafting or valve operations (2008-2016) and extubated within 24 hours were stratified according to extubation time between 06:00 and 18:00 (day) or between 18:00 and 6:00 (overnight). Outcomes including reintubation, mortality, and composite morbidity-mortality were evaluated using hierarchical regression models adjusted for Society of Thoracic Surgeons predictive risk scores. To further analyze extubation during the night, a subanalysis stratified patients into 3 groups: 06:00 to 18:00, 18:00 to 24:00, and 24:00 to 06:00.Results
A total of 20,758 patients were extubated overnight (52.1%) and were slightly older (median age 66 vs 65 years, P < .001) with a longer duration of ventilation (4 vs 7 hours, P < .001). Day and overnight extubation were associated with equivalent operative mortality (1.7% vs 1.7%, P = .880), reintubation (3.7% vs 3.4%, P = .141), and composite morbidity-mortality (8.2% vs 8.0%, P = .314). After risk adjustment, overnight extubation was not associated with any difference in reintubation, mortality, or composite morbidity-mortality. On subanalysis, those extubated between 24:00 and 06:00 exhibited increased composite morbidity-mortality (odds ratio, 1.18; P = .001) but no difference in reintubation or mortality.Conclusions
Extubation overnight was not associated with increased mortality or reintubation. These results suggest that in the appropriate clinical setting, it is safe to routinely extubate cardiac surgery patients overnight. 相似文献2.
3.
Stefaniuk Catherine M. Schlegelmilch June Meyerson Howard J. Harding Clifford V. Maitta Robert W. 《Journal of thrombosis and thrombolysis》2022,53(4):950-953
Journal of Thrombosis and Thrombolysis - Over the last few years data from our group have indicated that α-synuclein is important in development of immune cells as well as potentially... 相似文献
4.
5.
6.
Janet Fricke Carolyn Unsworth Diane Worrell 《Australian Occupational Therapy Journal》1993,40(1):7-15
This paper reports an inter-rater reliability study on the Functional Independence Measure (FIM). The FIM measures inpatient burden of care, as reflected in 18 self care items, rated on a seven point scale from dependent to independent. The subjects were 40 occupational therapists, divided according to experience with the FIM and randomly assigned to a FIM training or non-training group. Subjects rated video tapes of four stroke patients on transfers, bathing, dressing, grooming, toileting and eating items from the FIM. Rater consensus was calculated using the intraclass correlation coefficient (ICC), percentage agreement and a measure of disagreement. Rating accuracy was measured by comparisons with an expert rater. Ratings were most reliable when done by clinicians with no prior FIM experience, from the FIM training group. It is strongly recommended that all clinicians undergo FIM training before using this tool to ensure acceptable reliability. 相似文献
7.
8.
Human papillomavirus genotype distribution in low-grade cervical lesions: comparison by geographic region and with cervical cancer. 总被引:13,自引:0,他引:13
Gary M Clifford Rashida K Rana Silvia Franceschi Jennifer S Smith Gerald Gough Jeanne M Pimenta 《Cancer epidemiology, biomarkers & prevention》2005,14(5):1157-1164
Low-grade squamous intraepithelial lesions (LSIL) associated with certain human papillomavirus (HPV) genotypes may preferentially progress to cervical cancer. HPV genotyping may thus have the potential to improve the effectiveness of screening programs and to reduce overtreatment. LSIL cases (n = 8,308) from 55 published studies were included in a meta-analysis. HPV genotype distribution was assessed by geographic region and in comparison with published data on cervical squamous cell carcinoma (SCC). HPV detection in LSIL was 80% in North America but less than 70% in other regions, most likely reflecting regional differences in LSIL diagnosis. Among 5,910 HPV-positive LSILs, HPV16 was the most common genotype (26.3%) followed by HPV31 (11.5%), HPV51 (10.6%), and HPV53 (10.2%). HPV-positive LSILs from Africa were 2-fold less likely to be infected with HPV16 than those in Europe, and HPV-positive LSILs from North America were more likely to be infected with HPV18 than those from Europe or South/Central America. Interpretation for rarer genotypes was hampered by variation in HPV testing methodology. SCC/LSIL prevalence ratios indicated that HPV16 was 2-fold and HPV18 was 1.5-fold more common in SCC than in HPV-positive LSIL, thus appearing more likely to progress than other high-risk genotypes (SCC/LSIL prevalence ratios between 0.05 and 0.85). HPV53 and HPV66 showed SCC/LSIL ratios of 0.02 and 0.01, respectively. HPV genotype distribution in LSIL differs from that in cervical cancer, highlighting the importance of HPV genotype in the risk of progression from LSIL to malignancy. Some regional differences in the relative importance of HPV genotypes in LSIL were noted. 相似文献
9.
10.
Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery 总被引:3,自引:0,他引:3
Steven H. Belle Ph.D. M.Sc.Hyg. Paul D. Berk M.D. Anita P. Courcoulas M.D. M.P.H. F.A.C.S. David R. Flum M.D. M.P.H. F.A.C.S. Carolyn W. Miles Ph.D. James E. Mitchell M.D. Walter J. Pories M.D. F.A.C.S. Bruce M. Wolfe M.D. F.A.C.S. Susan Z. Yanovski M.D. Longitudinal Assessment of Bariatric Surgery Consortium Writing Group 《Surgery for obesity and related diseases》2007,3(2):116-126