全文获取类型
收费全文 | 27526篇 |
免费 | 1256篇 |
国内免费 | 151篇 |
专业分类
耳鼻咽喉 | 280篇 |
儿科学 | 492篇 |
妇产科学 | 455篇 |
基础医学 | 3608篇 |
口腔科学 | 551篇 |
临床医学 | 1668篇 |
内科学 | 7008篇 |
皮肤病学 | 384篇 |
神经病学 | 2315篇 |
特种医学 | 1086篇 |
外科学 | 4443篇 |
综合类 | 99篇 |
一般理论 | 6篇 |
预防医学 | 736篇 |
眼科学 | 496篇 |
药学 | 1668篇 |
中国医学 | 32篇 |
肿瘤学 | 3606篇 |
出版年
2023年 | 135篇 |
2022年 | 117篇 |
2021年 | 582篇 |
2020年 | 314篇 |
2019年 | 416篇 |
2018年 | 507篇 |
2017年 | 424篇 |
2016年 | 491篇 |
2015年 | 513篇 |
2014年 | 655篇 |
2013年 | 845篇 |
2012年 | 1439篇 |
2011年 | 1514篇 |
2010年 | 854篇 |
2009年 | 727篇 |
2008年 | 1241篇 |
2007年 | 1388篇 |
2006年 | 1348篇 |
2005年 | 1272篇 |
2004年 | 1248篇 |
2003年 | 1232篇 |
2002年 | 1292篇 |
2001年 | 722篇 |
2000年 | 794篇 |
1999年 | 737篇 |
1998年 | 344篇 |
1997年 | 259篇 |
1996年 | 213篇 |
1995年 | 242篇 |
1994年 | 231篇 |
1993年 | 212篇 |
1992年 | 656篇 |
1991年 | 585篇 |
1990年 | 565篇 |
1989年 | 577篇 |
1988年 | 517篇 |
1987年 | 488篇 |
1986年 | 449篇 |
1985年 | 452篇 |
1984年 | 260篇 |
1983年 | 215篇 |
1982年 | 103篇 |
1979年 | 241篇 |
1978年 | 131篇 |
1977年 | 112篇 |
1975年 | 102篇 |
1973年 | 97篇 |
1970年 | 103篇 |
1969年 | 118篇 |
1968年 | 97篇 |
排序方式: 共有10000条查询结果,搜索用时 328 毫秒
1.
Zhenzhen Zhang Mark Garzotto Tomasz M. Beer Philippe Thuillier Stephen Lieberman Motomi Mori 《Nutrition and cancer》2016,68(8):1309-1319
Animal and human studies suggest fish oil and green tea may have protective effect on prostate cancer. Fatty acid synthase (FAS) has been hypothesized to be linked to chemoprotective effects of both compounds. This study evaluated the independent and joint effects of fish oil (FO) and green tea supplement (epigallocatechin-3-gallate, EGCG) on FAS and Ki-67 levels in prostate tissue. Through a double-blinded, randomized controlled trial with 2 × 2 factorial design, 89 men scheduled for repeat prostate biopsy following an initial negative prostate biopsy were randomized into either FO alone (1.9 g DHA + EPA/day), EGCG alone (600 mg/day), a combination of FO and EGCG, or placebo. We used linear mixed-effects models to test the differences of prostate tissue FAS and Ki-67 by immunohistochemistry between pre- and post-intervention within each group, as well as between treatment groups. Results did not show significant difference among treatment groups in pre-to-post-intervention changes of FAS (P = 0.69) or Ki-67 (P = 0.26). Comparing placebo group with any of the treatment groups, we did not find significant difference in FAS or Ki-67 changes (all P > 0.05). Results indicate FO or EGCG supplementation for a short duration may not be sufficient to produce biologically meaningful changes in FAS or Ki-67 levels in prostate tissue. 相似文献
2.
3.
Masaru Sasaki Tsuyoshi Takahashi Soichiro Funaki Koji Tanaka Yasuhiro Miyazaki Naoko Ose Tomoki Makino Yukinori Kurokawa Makoto Yamasaki Kiyokazu Nakajima Yasushi Shintani Masaki Mori Yuichiro Doki 《Asian journal of endoscopic surgery》2021,14(1):116-119
We report a case of a diaphragmatic hernia after a heart transplant operation. A 43-year-old woman, who underwent orthotropic heart transplantation for hypertrophic cadiomyopathy two year earlier, presented with vomiting and epigastric pain. A computed tomography scan showed that the stomach and transverse colon were dislocated in the left thoracic cavity. We diagnosed left diaphragmatic hernia incarceration and performed laparoscopic repair of the diaphragmatic hernia. A 12 × 8 cm diaphragmatic defect was found intraoperatively on the ventrolateral aspect of the left diaphragm, and the stomach with volvulus had herniated into the thorax through the defect. The hernia was considered to be iatrogenic. The diaphragmatic defect was large, and the diaphragm was thinning. We closed the defect by mesh repair. Laparoscopic mesh repair of the diaphragmatic hernia could be performed safely and with minimal invasiveness. 相似文献
4.
5.
6.
7.
8.
Lesley A. Inker Morgan E. Grams Andrew S. Levey Josef Coresh Massimo Cirillo John F. Collins Ron T. Gansevoort Orlando M. Gutierrez Takayuki Hamano Gunnar H. Heine Shizukiyo Ishikawa Sun Ha Jee Florian Kronenberg Martin J. Landray Katsuyuki Miura Girish N. Nadkarni Carmen A. Peralta Dietrich Rothenbacher Mark Woodward 《American journal of kidney diseases》2019,73(2):206-217
9.
Kosuke Yoshihara Takayuki Enomoto Daisuke Aoki Yoh Watanabe Junzo Kigawa Nobuhiro Takeshima Hyoe Inomata Kana Hattori Masahisa Jinushi Hitoshi Tsuda Toru Sugiyama 《Cancer science》2020,111(9):3350-3358
Whether germline (g) breast cancer susceptibility gene (BRCA) mutations are located within or outside the ovarian cancer cluster region (OCCR) (1380‐4062 bp for gBRCA1, and between 3249‐5681 bp and 6645‐7471 bp for gBRCA2) may influence risk variations for ovarian cancers. This ad hoc analysis of the CHARLOTTE epidemiological study in Japan assessed the distribution of gBRCA1/2 mutations in patients with newly diagnosed ovarian cancer, and investigated an association between gBRCA1/2 mutation locations and ovarian cancer risk. Differences in patient background and clinical characteristics in subgroups stratified by gBRCA1/2 mutation locations were also evaluated. We analyzed the data of 93 patients (14.7%) from the CHARLOTTE study who were positive for gBRCA1/2 mutations. After excluding 16 cases with L63X founder mutation, 28 (65.1%) of gBRCA1 mutations were within the OCCR. Of 30 gBRCA2 mutations, 15 (50.0%) were within the OCCR. Of 27 patients (one patient excluded for unknown family history) with gBRCA1 mutations located in the OCCR, 11 (40.7%) had a family history of ovarian cancer; the proportion of patients with a family history of ovarian cancer and gBRCA1 mutations outside the OCCR was lower (13.3%). Sixty percent of patients with gBRCA1 mutations outside the OCCR had a family history of breast cancer; the proportion of patients with a family history of breast cancer and gBRCA1 mutations within the OCCR was relatively lower (33.3%). Understanding the mutation locations may contribute to more accurate risk assessments of susceptible individuals and early detection of ovarian cancer among gBRCA mutation carriers. 相似文献